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Flashcards in Module 5 EXAM PRACTICE Deck (105)
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1

High concentration of which which protein stimulates the development of anterior structures?

Bicoid

2

Conserved developmental genes can lead to _______ evolution.

parallel

3

The correct sequence in which Drosophila body axis genes act is:

egg-polarity genes--->gap genes --->pair-rule genes---->segment polarity genes--->homeotic genes.

4

Pair-rule genes loss-of-function mutation phenotype

Deletes every other segment

5

Gap genes loss-of-function mutation phenotype

Delete adjacent segments

6

Segment-polarity genes loss-of-function mutation phenotype

Affect polarity of segment; part of segment is replaced by mirror image of part of another segment.

7

Genes that regulate development are conserved. This means that they

have changed very little over the course of evolution.

8

When the mammalian Pax6 gene is overexpressed in flies,

flylike eyes develop.

9

The following are NOT characteristics of maternal effect mutations:

When mutant offspring arise they account for 50% of the offspring.

Mutant offspring arise from homozygous mutant fathers crossed to heterozygous mutant mothers.

Wild-type offspring arise from crosses of heterozygous mutant fathers regardless of the genotype of the mother.

Heterozygous mutant fathers crossed to homozygous normal mothers will not produce normal offspring.

10

The following are characteristics of maternal effect mutations:

Mutant offspring arise from homozygous mutant mothers irrespective of the genotypes of the father

11

Deletion of the _______ gene in Drosophila converts the 3rd thoracic segment into the second thoracic segment, resulting in a fly with 2 sets of fully formed wings.

Ubx

12

The expression of a zygotic gene product is based on the ____________________.

genotype of the zygote

13

TRUE or FALSE?

In Drosophila homeotic genes are present in 2 gene complexes.

True

14

A self-contained unit that is made up of other units is called a

module

15

Establishment of the dorsal-ventral axis of the Drosophila embryo:

Involves the nuclear localization of Dorsal protein in the ventral nuclei.

16

Many of the genes that control development encode _______ that act on proteins in a cascade of events.

transcription factors

17

Which of the following statements is true?

1. The transcription factors and the extracellular signals that govern pattern formation can be thought of as the molecular “black box.”

2. Developmental processes in both Drosophila and vertebrates are controlled by similar sets of genes.

3. Many regulatory genes are required to bring about the diversity of organisms that we observe.

Developmental processes in both Drosophila and vertebrates are controlled by similar sets of genes.

18

TRUE or FALSE?

The human Hox genes are similar in sequence to the homeotic genes found in Drosophila, but are not lined up in the the same order.

FALSE

19

The ability of an organism to modify its development in response to environmental conditions is called

developmental plasticity.

20

Which of the following is NOT a way plants differ from animals regarding regulatory genes that affect their development?

a) Plants have tremendous developmental plasticity.

b) Plant cells do not have MADS box genes and homeobox genes.

c) Future reproductive cells are not set aside during early plant development.

d) None of the above

e) Plant cells do not move relative to one another.

Plant cells do not have MADS box genes and homeobox genes.

21

Which scientist performed experiments with eyeless and Pax6?

Rebecca Quiring

22

The transcription factors that govern pattern formation in multicellular organisms, and the genes that encode them, are components of what biologists call the molecular _______.

tool kit

23

Ways that plants differ from animals regarding regulatory genes that affect plant development:

Plants have tremendous developmental plasticity.

Future reproductive cells are not set aside during early plant development.

Plant cells do not move relative to one another.

24

What is true of homeotic transformations in Drosophila?

they can be passed on from generation to generation

25

The action of genes controlled by _______ determines where and when they will be expressed or suppressed.

genetic switches

26

Which of the following is NOT a developmental environmental signal?

a) Temperature
b) Light
c) The presence of predators
d) All of the above are developmental environmental signals.

All of the above ARE developmental environmental signals.

27

List some developmental environmental signals

Temperature
Light
The presence of predators

28

What are the role and relationship of egg-polarity genes, segmentation genes, pair-rule genes, gap genes, and homeotic genes in Drosophila development?

??
EXTENDED RESPONSE


Egg polarity genes establish the anterior-posterior axis of the embryo using a concentration gradient of maternal mRNAs and proteins.
This gradient activates the gap genes, which divide the embryo into broad bands of head/thorax/abdomen.
Gap gene products activate pair-rule genes, which divide embryo into segments.
Pair-rule genes activate segment polarity genes in each segment, dividing each into anterior and posterior regions and aligned linearly.
Homeotic genes will determine the identity of each segment by determining which adult structure will be formed by the segment.

29

Flies have _______ eyes, while mammals have _______ eyes.

Flies have compound eyes, while mammals have _______ eyes.

30

dorsal

nuclear localization