Module 5 Unit A Flashcards

1
Q

What patients are eligible for selective GDM screening?

A

Women who are considered to be at low risk for GDM.
> 25
Not Hispanic, African American, Native American, South
or East Asian, or Pacific Islander
BMI 25 or less
No hx of abnormal glucose tolerance
No hx of adverse OB outcomes
No first degree relative with DM

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2
Q

What is the rationale for universal GDM screening?

A

90% of the population have risk factors and trying to identify 10% of women without screening is unnecessarily complex

Will identify women w/ previously undetected diabetes

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3
Q

When is the 50 g 1‐hour test screening test used?

A

It is used in early pregnancy with high risk patients.
If the results are negative, then it is repeated between 24 -28 weeks.

The test is used to test all pregnant women between 24 -28 weeks.

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4
Q

When is the 100 g GDM screening used?

A

The 3‐hour, 100 g OGTT is the common diagnostic test used in the United States when a 1‐hour screen is positive. The test is administered in the morning after an overnight fast.

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5
Q

When is the 75 g GDM screening used?

A

The one‐step method combines screening and diagnosis in one test. A 75 g oral glucose load is administered and plasma glucose levels are evaluated after 1 and 2 hours. Only one abnormal value is required for a diagnosis of GDM.

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6
Q

What is the GDM2 step testing approach?

A

The two‐step method, commonly known as the 1‐hour oral glucose tolerance test (OGTT), starts with a 50 g oral glucose load administered with plasma glucose levels evaluated after 1 hour. A positive screening result is then followed up with a 3‐hour oral glucose tolerance test for diagnosis. Screening and diagnosis occur in two separate steps. The 1‐hour OGGT is considered positive at levels exceeding 130–140 mg/dL

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7
Q

What is the GTM 1 step testing approach?

A

The one‐step method combines screening and diagnosis in one test. A 75 g oral glucose load is administered and plasma glucose levels are evaluated after 1 and 2 hours. Only one abnormal value is required for a diagnosis of GDM.

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8
Q

What is the threshold value for the one hour, 50 g gdm screening?

A

The 1‐hour OGGT is considered positive at levels exceeding 130–140 mg/dL.

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9
Q

What are the threshold values for a 3 hour, 100 g gdm screening?

A

Blood Sample National Diabetes Carpenter &
Data Group Coustan

Fasting 105 mg/dL 95 mg/dL
(5.8 mmol/L) (5.3 mmol/L)

1 hour 190 mg/dL 180 mg/dL
(10.5 mmol/L) (10.0 mmol/L)

2 hour 165 mg/dL 155 mg/dL
(9.2 mmol/L) (8.6 mmol/L)

3 hour 145 mg/dL 140 mg/dL
(8.0 mmol/L) (7.8 mmol/L)

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10
Q

What is the NDDG scale?

A

100gm glucose load

Fasting >/= 105

Postprandial 1hr >/= 190

Pp 2 hr >/= 165

Pp 3 hr >/= 145

Dx >/= 2 abnormal values

Diagnoses 3.3 %

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11
Q

What is the Carpenter/Coustan scale?

A

100gm glucose load

Fasting >/= 95

Postprandial 1hr >/= 180

Pp 2 hr >/= 155

Pp 3 hr >/= 140

Dx >/= 2 abnormal values

Diagnoses 5.1%

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12
Q

Why does ACOG support a 2 step testing versus one step testing?

A

It would increase (around 3x) the number diagnosed w/GDM w/o proven improvement in outcomes

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13
Q

How is GDM diagnosed in the pregnant patient?

A

A positive diagnosis of GDM traditionally has required that two or more threshold glucose levels on the 3‐hour test be met or exceeded. However, ACOG (2017) now states that one elevated value may be used to establish the diagnosis of GDM, noting that research evidence has demonstrated an increased risk for adverse perinatal outcomes with even one abnormal value.

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14
Q

What is the 1st line management of GDM?

A

Diet and exercise

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15
Q

When are diet and exercise indicated in GDM management?

A

If there are no OB contraindications to exercise.

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16
Q

When is blood sugar monitoring indicated in GDM management?

A

Diet diary for several weeks after dx to help assess dietary control - in conjunction w/ dietician

Fasting and 1 or 2 hour postprandial levels daily.

Record in logbook and review at prenatal visits

Fasting =95

Postprandial 1 hour =140

Postprandial 2 hour (more commonly used) =120

17
Q

How many times a day should a patient monitor their blood sugar?

A

4

18
Q

What is the fasting threshold value in patients with GDM?

A

95

19
Q

What is the 2 hour postprandial threshold value in a patient with GDM?

A

120

20
Q

When are medications indicated in GDM management?

A

When target can’t be consistently reached w/ diet and exercise

21
Q

What medication is 1st line in GDM management?

A

Insulin

22
Q

When can oral medications be used in GDM management?

A

If insulin cannot be safely injected or cannot be afforded.

23
Q

What oral medication is preferred in GD management?

A

Metformin

24
Q

When is fetal antenatal surveillance required in GDM management?

A

At 32 weeks if

On insulin – NST 2x/week

Pregestational diabetes

GDM and poor glycemic control

Pharm therapies - usually offered testing 2x/week starting at 32 wks w/ daily fetal movement counts

Diet controlled - 40 weeks

Ultrasounds 28 - 32 weeks

25
Q

What are the maternal and fetal indications for induction of labor?

A

Diet/exercise controlled - expectant mgmt up to 40 6/7 weeks

Good control on meds - 39 0/7 - 39 6/7 weeks

26
Q

What is the primary intra partum risk for a patient with GDM?

A

Neonatal hypoglycemia

27
Q

How does the nurse midwife manage a patient with GDM during the intrapartum period?

A

Prolonged labor women with T1DM - often require glucose and insulin to prevent ketosis

GDM and T2DM - labor insulin requirements vary, depending on the length of maternal disease, stage of labor, antepartum glycemic control and baseline insulin resistance

The use of various insulin/glucose protocols for diet and exercise controlled GDM is controversial and lacks strong research evidence

Some recommend using ACOG’s pregestational diabetes use of IV D5W w/ insulin drip to maintain serum glucose levels of 100 mg/dL or <110 mg/dL w/ hourly blood glucose checks

ACOGs GDM 2013, 2017 and 2018 bulletins do not discuss intrapartum management of GDM

According to the Fifth International Workshop Conference on GDM - most common practice has been to monitor and treat only those GDM women who received insulin therapy antenatally

28
Q

How does the nurse midwife manage a patient with TDM during the post partum period?

A

Not a contraindication to breastfeeding

Follow-up to assess for type 2 diabetes at 6-12 wks pp

Lifelong screening for DM recommended every 3 years

Typically, will not require any follow up in the immediate postpartum period

Once the placenta is delivered, euglycemia and resolution of the disease occurs

Optimal time to discuss reduction strategies to minimize the risk of T2DM

ADA and ACOG (2018) recommend repeat testing every 1- 3 years for women with a history of GDM.

4-12 weeks postpartum - 75g 2-hour OGTT to determine resolution

2-hour 75g OGTT postpartum results interpretation according to American Diabetic Association

*Must be confirmed by testing on a subsequent day

29
Q

What are the signs and symptoms of newborn hypoglycemia?

A

Can be asymptomatic, especially at first

Often vague and nonspecific

Jitteriness

Cyanosis

Apnea

Weak cry, can be high-pitched

Lethargy

Limpness

Refusal to feed

30
Q

What newborns are at risk for hypoglycemia?

A

SGA/FGR

Preterm infants

Post-term infants

Newborns who have experienced some form of distress prior to birth are at particular risk for hypoglycemia in the newborn period

Infants with mothers who have DM or GDM or received steroids

LGA

Due to a different mechanism which involves increased calorie consumption to maintain body temperature. This occurs in LGA infants whether or not the mother had DM, with the newborn’s risk increasing as birth weight increases

Sepsis, hypothermia, inborn errors of metabolism

31
Q

What are the optimal timing and intervals for glucose screening in the newborn?

A

Feed w/in 1 hr of birth and check BG 30 min after first feed

If refeed required, recheck 1 hr later

If BG good, feed on demand at least every 2-3 hr and recheck before feeds

Blood glucose levels initially fall to a nadir approx 1-2 hrs after birth.

The physiologic low occurs approx 1-1.5 hrs after birth

Levels stabilizing at 3-4 hrs

Routine blood glucose testing of term newborns after an uncomplicated birth is not recommended

Plasma or blood glucose concentration should be measured as soon as possible (minutes, not hours) in any infant who manifests clinical signs (see “Clinical Signs”) compatible with a low blood glucose concentration (ie, the symptomatic infant).

32
Q

What level of interprofessional collaboration is warranted for a newborn with hypoglycemia?

A

Refer to pediatrician