MODULE 6 : CONVERSION OF AMINO ACIDS TO SPECIALIZED PRODUCTS Flashcards

0
Q

Becomes atoms 4, 5, and 7 of purine

A

GLYCINE

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1
Q

Amino acid source of creatine and creatinine in the liver

A

GLYCINE

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2
Q

Amino acid that constitutes the major fraction of free amino acids in plasma together with glycine

A

a-ALANINE

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3
Q

Activates myosin ATPase, chelate copper and enhace copper uptake

A

B-ALANYL DIPEPTIDES

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4
Q

Amino acid Source of spingosine which is a component of sphingomyelin

A

SERINE

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5
Q

Amino acid which is the principal source of methyl groups in the body

A

METHIONINE

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6
Q

Amino acid precursor of Nitric Oxide, a neurotransmitter, vasodilator and smooth muscle relaxant

A

ARGININE

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7
Q

Converted to epinephrine and norepinephrine in neural cells

A

TYROSINE

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8
Q

An inhibitory neurotransmitter

A

GAMMA AMINOBUTYRATE

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9
Q

Becomes atoms 4, 5, and 7 of purines

A

Glycine

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10
Q

N and alpha carbons of this AA is incorporated into pyrrole rings and methylene bridge carbons of heme

A

Glycine

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11
Q

Together with glycine, this constitutes as the major fraction of the free AA in plasma

A

Alpha alanine

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12
Q

Formed from cytosine, carnosine and anserine

A

Beta alanine

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13
Q

Phosphorylation and dephosphorylation of these residues of enzymes involved in lipid and carbohydrate metabolism

A

Seryl
Threonyl
Tyrosyl

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14
Q

Principal source of methyl groups in the body

A

SAM

- S adenosylmethionine

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15
Q

Aa that contributes its carbon skeleton for the biosynthesis of the 3-diaminopropane portions of polyamines spermine and spermidine

A

Methionine

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16
Q

Methionine contributes its carbon skeleton for the biosynthesis of the _____________ portions of polyamines spermine and spermidine

A

3-diaminopropane

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17
Q

A precursor of thioethanolamine portion of coenzyme A

18
Q

Methionine that contributes its carbon skeleton for the biosynthesis of the 3-diaminopropane portions of polyamines _________________

A

Spermine and spermidine

19
Q

Cysteine is a precursor of ____________ portion of coenzyme A

A

Thioethanolamine

20
Q

Cysteine precursor of thioethanolamine portion of _____________

A

Coenzyme A

21
Q

Precursor of the taurine that conjugates with bile acid (taurocholic acid)

22
Q

Cysteine is a precursor of the _________ that conjugates with bile acid (taurocholic acid)

23
Q

Cysteine is a precursor of the taurine that conjugates with ____________ (taurocholic acid)

24
De carboxylation of histidine will result to?
Histamine
25
What catalyzes the decarboxylation of histidine to histamine?
Broad spec aromatic L amino acid decarboxylase
26
Formamidine donor for creatine synthesis
Arginine
27
_________ via ornithine produces putrescine, spermine and spermidine
Arginine
28
Arginine via ________ can synthesize putrescine, spermine and spermidine
Ornithine
29
24 hour excretion of this metabolite is proportionate to muscle mass and is a useful indicator of kidney function
Creatinine
30
This AA serves as a precursor of the intercellular signaling molecule NO
Arginine
31
These polyamines function in cell proliferation and growth
Spermine and spermidine
32
Spermine and spermidine A. Polyamide B. Polyamine C. Neurotransmitter
B. Polyamine
33
Hydroxylation of tryptophan to 5-hydroxytryptophan is acted upon by what liver enzyme?
Tyrosine hydroxylase
34
Subsequent decarboxylation of tryptophan forms what vasoconstrictor?
Serotonin
35
Subsequent decarboxylation of this AA forms serotonin
Tryptophan
36
Kidney and liver tissue, and the bacteria, converts tryptophan to __________ then to _________
Tryptamine | Indole 3 acetate
37
Neural cells convert tyrosine to ______ and _______
Epinephrine | Norepinephrine
38
Neural cells convert __________ to epi and norepi
Tyrosine
39
AA that serves as a precursor of T3 and T4
Tyrosine
40
Decarboxylation of L-glutamate will produce what neurotransmitter?
GABA
41
GABA is formed from the decarboxylation of what AA?
L- glutamate
42
What enzyme catalyzes the decarboxylation of L- glutamate?
L-glutamate decarboxylase