Module 7 Flashcards

(59 cards)

1
Q
The brain's blood dependence: 
brain cells depend on: 
blood supplies brain cells with: 
blood also removes ? from? 
the cells of the brain have no mechanism to ? they have complete dependence on
A

uninterrupted and oxygenated blood

nutrition

  • glucose
  • oxygen

metabolic waste (carbon dioxide) from nerve cells

-store glucose or oxygen for later consumption/ blood flow

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2
Q

brain blood flow and stroke

-without adequate blood supply, the brain can only function ? before the cell bodies are

interruption of blood flow for 4-6 minutes results in?

  • damage occurs to the ?
  • the area that surrounds the core infarct is called the
  • neurons in the area of the prenumbra may survive for about ? without alternate circulation, and up to ? if there is some degree of collteral blood supply
A

for a few minutes/ cell bodies are irreversibly damaged

irreversible brain damage

  • core cells that are the center of where the infarction occured
  • ischemic penumbra

20 minutes/ 6-8 hours

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3
Q

Acute stroke:
two types
ischemic: inadequate blood flow to the brain results in ?

hemmorhagic:
- rupture of a blood vessel
- blood which is toxic to brain tissue
- blood also causes swelling of ? swelling can further restrict ?
- issue with tissue damage and potential increasedintra cranial pressure due to the ? as well as ?

A

damage to the brain tissue

causes bleeding in the brain

  • collects in brain tissue
  • brain tissue/ blood flow to other neighboring brain tissue
  • bleed itself/ swelling as a reaction to the blood
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4
Q

Comprehensive Stroke Center:
hospital certified by the ?
Early management of acute ischemic stroke: a guideline for ?
this designation/certificated is given to center that are able to:
.. and… treat all strokes utilizing ?
-provide ? for blood clot removal
-provide

A

American Heart Association/american stroke association stroke leadership council

healthcare professionals from the american heart association/american stroke association

  • quickly and effectively/ medications to resolve blood clots
  • catheter based procedures
  • neurosurgical services
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5
Q

Treatment for ischemia in the brain:
what restores blood flow:
-
-

A

tPA (tissue plasminogen activator) - drug

thrombectomy: procedure (vascular/neurosurgery) - larger clot in larger vessel

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6
Q
Tissue plasminogen activator: 
tPA (generic name is ? ) approved by FDA in ? 
-dissolves blood clots that are 
-given to patients via 
-administered within ? 
limits risk of ? 
....
consider timing of
A
alteplase/ 1996 
blocking blood flow to the brain 
- IV 
-3 hours of symptoms onset 
-brain damage and functional impairment 
-hemorrhage (risk and contraindication) 
-SLP intervention
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7
Q

Thrombectomy:
in some hospitals can be completed up to? (if imaging shows ?)
-more typically, the window is … from symptom onset (with assumption that damage to neural tissue will not be improved by ?)
time of onset is tricky calculaton
-…. onset
-variation in ?

A

24 hours after onset of ischemic stroke ( there would be therapeutic benefit)

6 hours (intervention)

unwitnessed
A&P of individual patients

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8
Q

Thoughts about stroke and COVID-19:
risk of worse outcomes with COVID-19 patients with history of ?
risk of stroke with COVID:
-two studies ad meta-analysis suggests that stroke is associated with ?

covid-19 itself may contribute to development of?
-prevalence of ischemic stroke is ?
true association remains ?
further investigation and more consistent covid screening ?
consider the non-COVID patient: risk of greater ? lasting deficits from stroke as patients are less likely to ?

A

stroke

2.5 fold increase in likelihood of severe COVID-19 with a trend in increased mortality

vascular events
-1.6%
unclear
-needed

injury/ seek medical treatment due to COVID

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9
Q

Acute Ischemic Stroke and COVID-19 an analysis of 27, 676 patients:
investigated ?
patients with covid with or without ischemic stroke and
acute ischemic stroke patients with and without ?

A

risk factors, comorbidities and outcomes between

covid

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10
Q

total of 103 patients developed ? among 8136 patients with covid

among all patients with covid the proportion of patients with hypertension, diabetes, hyperlipidemia, atrial fib, and congestive heart failure ?

acute ischemic stroke was associated with discharge to ?

A

acute ischemic stroke

was significantly higher among those with acute ischemic stroke

destination other than home or death

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11
Q

Acute ischemic stroke was infrequent in patients with ? and usually occurs in the presence of other ?

the risk of discharge to destination other than home or death increased 2-fold with occurence of ?

A

cardiovascular risk factors

acute ischemic stroke in patients with COVID 19

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12
Q
Stroke - intervention/facilities:
... care
Subacute care: 
depends upon ? 
-consider 
-... patients 
sadly, can depend upon 
options: 
... rehab 
-... rehab 
long-term ? 
home (... considerations) 
-
-
A

acute care

level of function

  • rehab needs
  • ambulatory patients

finances

acute rehab (inpatient rehab) 
-sub-acute rehab (SNF) 
-care facility (frequently SNF first) 
(safety considerations) 
-home health 
-outpatient rehab services
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13
Q

Brain tumors:
a neoplasm is an area of uncontrolled ?
tumors result from an improper expression of ? and a decrease in expression of ?
-angiogenesis also promotes ? this is the formation of new blood vessels which promotes?
tumors in the brain can be ?
metastatic tumors in the brain are frequently metastasis of cancers including ?
they can also come from ? and from ?
spread results from cells traveling through the ?

A

growth of body tissue/ includes the glia

oncogenes (coding proteins involved with cellular growth) / tumor supressor genes

tumor growth / growth of tumor tissue

primary or metastatic

breast, lung, colon/ lymphomas and melanoma

lymphatic system or blood vessels

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14
Q
Neuroglial cells- functions 
astrocytes (CNS)
-form a complete ? 
-contribute to the blood-brain barrier by restricting ? 
form ? 

Oligodendrocytes:
form ? around axons in the CNS

microglia:
migrate to a site of ?

ependymal cells:
form the ?

Schwann cells (PNS) 
-form the ? 
constitute ... around fibers in the PNS
A

lining around the surface of the brain

  • permeability of ionic substances across the blood vessels
  • scars around a cerebral infarct

myelin sheaths

brain lesion and engulf cellular debris to remove it

membranous lining of the ventricular cavity

myelin sheath around axons in the PNS
fibrous connective tissue

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15
Q
Brain Tumors Can Be: 
are staged in grades (1-4)
Grade 1: 
Grade II: 
Grade III: 
Grade 4:
A

non-cancerous or very slow growing
cancerous but slow growing (cells look closer to normal)
cancerous y grow faster than grade 1 and II (more cell abnormalities)

fast growing with greater cell abnormalities (may also have necrotic tissue; develop own blood vessels, spread to other parts of brain)

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16
Q

Brain Tumour Types:
astrocytoma:
arise from
the worst brain tumour is the ?

ependymoma:
arise from

oligodendroglioma:
arise from ? frequently found in ?

A
astrocytes 
Glioblastoma (GBM) - a type of astrocytoma

ependymal cells lining the ventricles

oligodendrocytes - frequently found in the frontal region of the adult brain

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17
Q

Brain Tumors (Non-malignant)
Meningioma: arises from ?
usually ?

Acoustic neuroma (vestibular ? ) 
arise from the ? and are typically located at the 

symptoms can include: and can cause other ?
-…,…,…
cause ?

Pituitary adenomas:
cause ? and can produce ? due to ?

A

meninges
non-malignant

schwannoma
-nerve sheath/ cerebllopontine angle

impaired hearing acuity and equilibrium / other deficits (tumour and post-op)
-facial weakness, dysphagia, dysphonia
hydrocephalus (obstruct fourth ventricle)

hormonal dysfunction / visual deficits / compression of optic chiasm

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18
Q
Diagnosis and TX planning: 
... planning is frequently completed at a ? 
typically conducted ?
include: 
-
-
-
-
-
-
-
A

medical/surgical / neuro tumour board meeting
weekly

  • neuroradiologist
  • pathologist
  • medical oncology
  • radiation oncology
  • neurosurgery
  • neurology
  • mid-level providers
  • SLP
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19
Q

Treatment options:
medical ?
-

radiation?

  • … therapy
  • several ?

neuro?

all of the

what will?

… of the above

A

oncology
-chemotherapy

radiation oncology

  • radiation therapy
  • several types

neurosurgery

  • all of the above
  • timing be?
  • none of the above
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20
Q
SLP role:
Communication ? and swallowing ? 
pre-treatment ? 
post-surgery 
intervention during ? as needed
post-treatment ? 
-treatment as 
-...
participation in ?
A
function
baseline measures 
functional measures 
medical and radiation oncology treatment, as needed
functional meaurements 
-appropriate 
-education 
awake craniotomy
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21
Q
Dementia: 
an ? term 
a group of disorders that affect 
affects: 
-
-
-

2 types:
… dementia
… dementia

A

umbrella term
brain function

  • thinking
  • behavior
  • ability to complete ADL

cortical dementia (alzheimers)
sub-cortical dementia (Parkinsons dementia)
combo

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22
Q

Types of dementia:

alzheimers:
- the most common
- accounts for ?

.. dementia:
second most
-accounts for

Lewy body:
accounts for

frontotemporal:
accounts for

other

A

form of dementia
40-70%

vascular dementia

  • common from
  • 15-25%

2-20%

2-4%

brain injury 
ETOH
HIV
PD
HD
creutzfeldt jakob
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23
Q

Role of SLP:
communication:
assessment of
educate?

-to maximize
intervention with SLP should be ?

Swallowing: 
assessment of ? 
-may be best to ask what will be 
-establish 
consider 
treatment may be ? due to ?
A

current function
-medical professionals and family members

strategies
-environmental
-comm. function
relatively short in duration

  • current function
  • done regarding results
  • least restrictive PO diet
  • patient and family wishes
  • limited / cognitive comm. dysfunction
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24
Q
Tube feeding in severe dementia: 
main results:
-no .. trials identified 
-seven 
-six assessed ? 
-the other study assessed ?
there's was no evidence of increased ? 
none of these studies examined ? and there was no evidence of benefit in terms of ? 

authors conclusions:
despite the very large number of patients receiving this intervention there is insufficient evidence to suggest that enteral tube feeding is ?
data are lacking on adverse effects of ?

A

randomised controlled trials identified

  • observational controlled studies identified
  • mortality
  • nutritional outcomes
  • survival in patients receiving enteral tube feeding
  • QoL nutritional status or prevalence of pressure ulcers

beneficial in patients with advanced dementia

-this intervention

25
``` What is delirium: a state of characteristics of delirium include: difficulty difficulty confused about hallucinations - ... that are not develops over a short has ? ```
``` severe confusion -thinking clearly -to attend -situation/circumstances hearing or seeing things not present ``` period of time fluctuating symptoms
26
ICU Delirium: approx. ... patients in the ICU experience delirium approx. ona. ventilator experience delirium (while on or immediately following) linked to negative ? increased? decreased ? and greater ?
2/3 7/10 medical outcomes n(increases LOS in ICU and Hospital) , costs, survival, long-term cognitive dysfunction
27
``` Advice for PT and family/friends speak? use ? remind patient of talk about bring ? decorate room with provide patient with if your loved one has delirium you might be asked to ? ```
``` calmly/simple words or phrases day and date family and friends glasses/hearing aids calendars, posters, family pictures favorite music/tv delirium/ sit and help calm them ```
28
Delirium prevention and Management: delirium is one area that is part of a larger there are specific components of care that include care programs include: -.. assessment and management -reducing ? to allow for electing the best ... for individual pt's delirium? early engaging with
overall care plan in ICU delirium in plan of care implemented ``` pain sedatives/ awakening and spontaneous breathing -analgesics/pain meds -prevention, assessment, mgmt mobility/exercise family members ```
29
``` Post intensive care syndrome: physical, psychological, and cognitive symptoms that persist ? physical symptoms include: - -.. difficulty -... and ... ``` ``` psychological symptoms can include: - - - - ```
after critical illness - weakness and balance issues - breathing difficulty - pain and numbness anxiety depression PTSD Sleep disturbance
30
Cog. Symptoms of PICS: difficulty w/ memory increased
concentration.attention deficits processing time
31
Traumatic Injury: Traumatic injury is a term which refers to ? which require ? the insult may cause system shock called ? may require immediate ?
physical injuries of sudden onset and severity/ immediate medical attention/ shock trauma/ resuscitation and interventions to save life and limb
32
``` Metabolic, endocrine and immunologic response to trauma: body response to trauma includes: ... an increase in use of increased increased development of -higher blood glucose levels have been found to be associated with ? ```
tachycardia use of oxygen respiratory rate insulin resistance fatal outcomes in trauma patients
33
Trauma statistics: center for disease control 10 leading causes of death in 2017 ? in groups from ages 1 to 44 unintentional injury is ranked for persons from 45-64 years unintentional injury is ranked
1st 3rd
34
History of Care for traumatic injury: care and transportation build from medical lessons learned from ? legislation in 1966: accidental death and disability: the neglected disease of modern society - advocated for strong govt. leadership to develop national highway safety act: provided funding from congress to reduce mortality from Illinois developed the first statewide ? which extended the knowledge gained at Cook county hospital in Chicago which was one o the first
1st and 2nd world wars trauma care as well as funding for research motor vehicular accidents trauma system/ first true trauma centre in the US
35
The American Trauma System: designed to provide an ? Run at the state and local level with guidance by ? -geographic distribution of trauma system resources correlates with ? lower fatality rates seen in areas with more? care begins in the field with ? 4 levels of trauma center -level I trauma center: comprehensive regional resource providing ? typically located in ?
organized response to injury - national societies - outcomes/ clustered trauma centers emergency medical services personel I-IV -total care for every aspect of injury/large cities or densely populated areas
36
Air Care: modern air medical transport began in ? with what program ? the first hospital-based air medical transport in US by 1990 there were more than ? in operation air care reduces the amount of ? to expidiate evacuation within? it is estimated that there are nearly ? annually with an additional 150,000 patient flown by ? each year in the US
1972/ Flight for life program at Anthony's hospital in Denver 170 air transport programs pre-hospital time / golden hour 400,000 helicopter transports /by fixed wing aircraft
37
Air care flight physiology: oxygenation changes during ? (consideration for ... levels, which may result in need for ? prior to flight) a pneumothorax should be addressed prior to flight because of risk of ? penetrating ocular injuries should be transported at the ? due to the impact of intraocular pressure on the retina expansion and contraction of gasses also have painful ? sites impacted include the ? Gas within the body expands during? patients with abdominal trauma should have a ? in place to avoid any mechanical effects Temperature ? aircraft temperature is controlled but if there is failure of that system, a plan must be inplace as hypothermia has been found to dramatically increase ? also must consider the concern of the temperature of ? within aircraft
ascent from ground to higher altitudes/ hemoglobin levels/ blood transfusion expansion or development of a tension pneumothorax during flight lowest possible altitude mechanical effects on the body/ middle ear, teeth, sinuses, and GI tract / ascent/ NGT decreases with ascent/ mortality in trauma patients/ medications and supplies
38
``` At the hospital: injuries include: known unknown -... issues that result from ? - other considerations: patient's ```
known injury unknown injury -fistulas life-saving treatment -intubation/extubation/tracheostomy patients past emdical and surgical hx
39
``` impact of traumatic injury: patients require family academic / occupational need for ```
contiuum of care family impact impact of injuries ongoing support services
40
Other factors: I... location of family
``` insurance injury (out of town, state, international travel) dynamics: discharge panning - need for 24 hour care ```
41
``` SLP evaluation and intervention: deficits including: -disorders of -...impairment ...impairment ```
consciousness comm. impairment swallowing impairment
42
``` Dysphagia assessment decision making: special considerations for this patient population: patient positioning: -unstable -external ``` aility to safely ? -... deficits ...fixators -... type and timing of ?
restrictions and limitations - spine - external ventricular drain (EVD) transport to radiology -cognitive comm. deficits external fixators -IVs and chest tubes dysphagia assessment
43
Swan-Ganz Catheter: inserted into the right side of ? can measure ? measures pressure in the
heart to monitor heart functions - blood flow in the right atrium and right ventricle - pulmonary artery
44
``` Dysphagia assessment decision making in trauma: what is the appropriate timing of the eval: -time of -medication -... factors -NGT to Small and large Ileus: obstruction of -post-surgical /? ```
``` day (alertness) delivery (pain and level of alertness) factors (is it safe to assess/safety for PO intake) -suction bowel issues -part of intestine opioid use ```
45
``` Dysphagia Assessment decision making: which test provides the best ? FEES: contraindications include: ... fractures ability to ... (risk of bleeding) ``` ``` fluoroscopy tower versus C-arm -. - -transfer - ``` If MBS which contrast to utilize (whose decision) -... ...
assessment nasal/facial participate/cooperate anticoagulation weight positioning transfer constraints cognition (Ranchos IV or lower-likely not) radiologist decision water-soluble barium
46
Covid consideration: trauma is typically not an anecdotally a large number of patients have been admitted to the hospital status post fall/trauma have been found to be
elective hospitalization COVID positive
47
``` Assessment: limited in acute care due to level of formal assessment may not be ? -length of time to -higher level tasks on ``` formal assessments include: SCATBI: CLQT: RBANS:
function/severity of injury possible - assess - assessment scales of cognitive ability in traumatic brain injury cognitive linguistic quick test repeatable battery for the assessment of neuropsychological status
48
The montreal cognitive assessment a brief 30 question test that helps healthcare professionals detect ? allowing faster ? and patient ? MoCA is the most ? available for detecting ? measuring ? and multiple ? which are important components not measured by ?
COGNITIVE IMPAIRMENTS VERY EARLY ON / diagnosis/care sensitive test / alzheimers disease/ executive functions / cognitive domains/MMSE
49
In 2003, after analysis of the 2000 study results, a few elements of the test were optimized and a new validation study was copleted in 2003-2004 which confirmed the test's discirminatory ability to distinguish ?
normal controls from subjects with mild cognitive impairment or mild alzheimers disease
50
``` Cognistat: Standardized for ? -..,...,... how long to administer or less with? ``` ``` evaluates: - -..skills - - - ```
adolescents and adults stroke, TBI, dementia 15-20 or less with screening ``` language spatial skills reasoning memory calculations ```
51
``` Mild TBI/Concussion identification of patient's who have potentially -nursing ? -may or may not involve imaging may be ``` mechanism to educate patients and families about mechanism to see these patients for athletes versus ? - different - pre-testing for athletes mayhave been
sustained a concussion -identifiers -loss of consciousness normal potential issues that may arise outpatient follow up non-athletes -referrals for outpatient completed
52
``` Signs and symptoms of Mild TBI: social: interactions with maintaining difficulty with participating in -engaging in -difficulty taking perspective of ```
``` others a topic in convo word-finding in convo social roles as a spuse, parent, friend activities like work and school others ```
53
``` Signs and symptoms of mild TBI: mental difficulty feeling difficulty with difficulty with difficulty with difficulty wih ```
``` concentrating slowed down or sluggish memory problem solving decision making multi-tasking and completing daily activities ```
54
``` Signs and symptoms of mild TBI emotional: change in changes in - -emotional -easily -... ```
``` personality mood/sadness irritability outbursts overwhelmed nervousness ```
55
``` Sign and symptoms of Mild TBI: physical ... loss of impaired slower .. or... blurry sleeping ```
``` headache balance coordintion/dizziness reaction time nausea or vomiting blurry vision difficulty ```
56
The 3 ounce water test/challenge: initially information for swallow screening published in several other publications followed by ? lacked adequate ? debra suiter Ph.D. and steven leder Ph.D. completed further investigation of this screening and there is now a great deal of ? ``` use by use by initially used with ? subsequent investigations included varied ? not just ? includes other ? ```
1992 different authors/ sample size and lacked statistical power evidence available ``` slps nurses stroke patients populations stroke/ neurological and pulmonary disorder and specific surgeries ```
57
Yale swallow protocol: brief ... exam .. water challenge
cognitive assessment oral mechanism exam 3 oz
58
``` 3 oz water test: SLP involvement in developing and or maintaining typically completed by assess patient for ? - - administer ? -...sips ```
``` this screening program nursing appropriateness to administer PO -alertness intubation ``` 3 oz of water consecutive sips
59
Performing RN stroke swallow screen: step 1 step 2 step 3
initial assessment swallow challenge documentation