Module 9 - Sleep (Test 2) Flashcards

1
Q

What sleep does

A
  • Essential biological process and need for wellbeing
  • Stimulates and reinforces immune function
  • Regulation of mood and stress processes
  • Consolidation of learning and memory
  • Maintenance of cognitive functions
  • Regeneration of energy stores of muscle and nerve cells
  • Regulation of functions such as blood glucose (disturbed metabolism, risk of weight gain)
  • Elimination of toxins
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2
Q

Polysomnography

A

A medical examination consisting of recording, during the patient’s sleep, several physiological variables

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3
Q

Laboratory assessments of sleep

A
  • Polysomnography
  • Respiratory and cardiac rhythm
  • Electroencephalogram
  • Electromyogram of the muscles of the arms of legs
  • Nocturnal blood-oxygen saturation
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4
Q

The sleep cycle

A
  • 90 minutes
  • stage 4 sleep decreases and REM sleep increases with every cyle
    Stage 1 - 4&raquo_space; 4 - 2&raquo_space; REM Sleep
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5
Q

Delta Waves

A

Stage 3-4 (Deep sleep)

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6
Q

Alpha Waves

A

Awake

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7
Q

Two stages with practically identical brain waves

A

Stage 1 and REM sleep

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8
Q

Circadian Rythms (Biological Clock)

A
  • Occur on a 24h cycle
  • Include sleep and wakefulness
  • Can be altered by artificial light
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9
Q

Light’s role in the circadian rhythm

A

Triggers the suprachiasmatic nucleus to decrease (in the morning) melatonin from the pineal gland and increase (in the evening) it at nightfall

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10
Q

Night terrors

A

Confusion and terror but still asleep

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11
Q

Parasomnias happen in …

A

Deep sleep or REM sleep

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12
Q

Confusional Awakenings (P)

A

Episodes of confusion occuring during or after awakening

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13
Q

Sleepwalking (P)

A

Walking (or doing something else!) during sleep - Often due to sleep

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14
Q

Hallucinations (P)

A

Hypnagogic (while falling asleep) or hypnopompic (while awakening)

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15
Q

Sleep rhythms (P)

A

Repetitive movements of the muscles (head, neck)

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16
Q

Myoclonia (P)

A

Rapid muscular tremors while falling asleep

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17
Q

Sleep paralysis (P)

A

Muscle atonia during sleep

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18
Q

REM sleep behavior disorder (P)

A

Acting out dreams physically

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19
Q

Bruxism (P)

A

Grinding Teeth

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20
Q

Somniloquy (P)

A

Talking in your sleep

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21
Q

Enuresis (P)

A

Bed Wetting

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22
Q

Exploding head syndrome (P)

A

Intense migraine

23
Q

Narcolepsy (Gélineau disease)

A

Paradoxal sleep attacks that happen at any time

24
Q

Narcolepsy stats

A
  • 1 in 2800 people in North America
  • manifests in adolescence
  • gender ratio : 1:1
  • Multiple awakenings at night
25
Can narcolepsy be cured?
No but symptoms can be treated with medication
26
Narcolepsy treatments
- Pharmacological treatment (modafinil) reduces falling asleep in 70% of cases - Low-dose antidepressants - Behavioural treatment: helping the person learn to live with the disease and reduce the risk of accidents
27
Restless leg syndrome (Willis Ekbom syndrome) (D)
- irresistible urge to move your legs during period of rest or inactivity - discomfort/pain - relieved or suppressed by movement
28
Restless Leg Syndrome stats
- 10% of Can. population (1/3 moderate to severe) - Stable or deteriorates up to age 70-80 - Female:male ratio 2:1 - 40-90 % positive family history
29
Restless leg syndrome causes
- Central nervous system disorder - Genetics - Iron deficiency ?
30
Restless Leg syndrome treatments
- Physical activities of mild to moderate intensity - leg massages - hot or cold bath - mental distraction - vitamin supplements (iron, magnesium, vitamin C) - dopamine agents
31
Sleep apnea (D)
Respiratory disorder is characterized by frequent pauses in respiration (apnea) or decreased respiratory flow (hypopnea) , decrease of oxygen
32
sleep apnea is 2 x more common in...
men
33
Risk factors for sleep apnea
- Obesity - Age - Gender - Certain abnormalities of the airways or jaws - Genetic factors - Neck Circumference - Nasal Obstruction - Alcohol consumption and smoking - Certain meds - Type 2 diabetes
34
2 types of causes to sleep apnea
Obstructive and Neurological
35
Obstructive causes
- Overweight - Large tonsils - Excess of fatty tissue in the throat - Lower Jaw too short or recessed
36
Neurological causes to sleep apnea
Central sleep apnea syndrome (CSAS)
37
Apnea treatments
CPAP (continuous positive airway pressure) device, dental prosthesis, positional therapies
38
Effect of aging on sleep
- Deterioration of the hypothalamus (age-related) affects circadian rhythms - Increase in cortisol level - Decreased sleep time due to reduction of the secretion of human growth hormone - Reduced sensitivity of the retina to light
39
Insomnia (D)
- Most common sleep disorder
40
DSN definition of insomnia
1. Difficulty initiating sleep ( 30mins+ 3x/week) 2. Difficulty maintaining sleep ( frequent awakenings or problems falling asleep after awakenings) 3. Early morning awakenings ( awakening with the inability to fall back to sleep again 4. Has to interfere with a person's life
41
medical cause of insomnia
chronic pain, asthma, reflux, meds
42
psychological cause of insomnia
depression, anxiety, stress, mania
43
life causes of insomnia
children/parents, school, work, too many rotating shifts, habits.
44
Predisposing factors of insomnia
Age, gender, family history, anxiety, etc.
45
Preticipating factors of insomnia
(life bombs) : divorce, grief, etc
46
Perpetuating factors of insomnia
(becomes a bad habit) : habits & behaviours, beliefs, attitudes
47
Therapeutic strategies for insomnia
- Relaxation, diaphragmatic breathing, mediation, biofeedback, imagery - Cognitive behavioural therapy - Pharmacotherapy
48
When should a person use pharmacotherapy to treat insomnia?
- Situational insomnia ( stress, change of environment, time zone) - Initial therapy for chronic insomnia - Insomnia associated with a medical or psychiatric condition
49
Types of pharmacological treatments for insomnia
- benzodiazepine - other non-benzodiazepine hypnotics - Rx off-label antidepressants, anti-psychotics - antihistamines - natural products/otc (valerian, melatonin)
50
Positive effects of using pharmacological treatments to treat insomnia
- Reduction of sleep latency and awake time during the night - Reduction of the number of awakenings - Overall sleep time increase
51
Negative effects of using pharmacological treatments to treat insomnia
- Increase stage 2 sleep - Reduced stages 3-4 and REM sleep - Anterograde amnesia
52
Risks and limitations of BZD and non-BZD
- Cognitive, psychomotor, neuropsychological and residual daytime fatigue problems - Danger of abuse in people dependent on alcohol or other substances - 40% of patients don't respond - special management in elderly and pregnant or breastfeeding women
53
Cognitive behavioural therapy for insomnia
1. Sleep hygiene (favourable conditions for sleeping) 2. Behavioral (Restriction of time spent in bed) 3. Cognitive ( Beliefs and attitudes)
54
Why do we dream?
1. To develop and preserve neural pathways 2. To make sense of neural static 3. To reflect cognitive developpement