Molecular Genetics Flashcards
(23 cards)
Amino Acids
An organic monocular processing both carboxyl and amino groups.
Activator
A protein that binds to DNA and stimulates gene transcription.
Anticodon
A nucleotide triplet at one end of a tRNA molecule that recognizes a particular complementary codon on an mRNA molecule.
Base paring rules
A T
C G
Cell differentiation
The structural and functional divergence of cells as they becomes specialized during a multicellular organism development.
Constitutive gene
A gene that is transcribed at a relatively constant level regardless of the cell environmental conditions.Unlike facultative genes that are transcribed only when needed, constitutive genes are expressed continuously. It is because constitutive genes such as housekeeping genes code for products with housekeeping functions in cells, e.g. maintaining the basic cell processes or structure.
Coding strand
The opposite strand (that is, the strand with a base sequence directly corresponding to the mRNA sequence) is called the coding strand or the mRNA-like strand because the sequence corresponds to the codons that are translated into protein.
Codon
A three nucleotide sequence of DNA or mRNA that specifies a particular amino acid or terminal signal; the basic unit of the genetic code
DNA Ligase
A linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3’ end of DNA fragment to the 5’ end of another DNA fragment
DNA polymerase
An enzyme that catalyzes the elongation of new DNA by the addition of nucleotides to the 3’ end of an existing chain. There are several different DNA polymerases; III and DNA polymerase I play major roles in DNA replication.
Embryonic induction
The influence exercised by parts of the embryo, which causes groups of cells to proceed along a particular path of development
Exons
An exon is the portion of a gene that codes for amino acids. And will get expressed.
Gel electrophoresis
Gel electrophoresis is a method for separation and analysis of macromolecules and their fragments, based on their size and charge.
Gene expression
The process by which DNA directs the synthesis of proteins or in some cases, just RNAs.
Gene induction
Activation of an inactive gene.
Gene repression
The inhibition of a gene’s expression, this is typically caused by the change in the activity of a regulatory protein.
Genetic code
Genetic code
relationship between the sequence of bases in nucleic acid and the order of amino acids in the polypeptide synthesised from it. A sequence of three nucleic acid bases (a triplet) acts as a codeword (codon) for one amino acid.
Genetic engineering
The direct manipulation of genes for practical purpose.
Genetic transplantation
The field of biology and medicine relating to the genes that govern the acceptance or rejection of a transplant.
Helicase
The enzyme that unzips the double helix DNA strand.
Homeotic genes
A developmental gene that specifies the anterior-posterior axis, as well as segment identity during the early embryonic development of certain organisms, such as metazoans.
HOX genes
Any of the developmental control genes involved in establishing the anterior-posterior axis and the identity of each body segment in organisms, especially during early embryonic development.
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