Monobactams Flashcards
1
Q
What is a Monobactam?
A
Unique class of beta-lactams with a four-membered ring lacking a fifth or sixth member, like other beta-lactams
2
Q
Only available agent of Monobactams
A
Aztreonam (Azactam)
3
Q
Monobactams Distribution
A
distribute well into most tissues; not extensively bound to proteins
4
Q
Monobactams Half life
A
3 hours
5
Q
Monobactams Elimination
A
excreted primarily unchanged by glomerular filtration
6
Q
Monobactams Mechanism of Action
A
interfere with bacterial cell wall synthesis; safe toxicity profile.
7
Q
Monobactams Clinical Uses
A
treating urinary tract infections (UTIs) and respiratory tract infections.
