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MRCP Pharmacology > Monoclonal Antibodies > Flashcards

Monoclonal Antibodies Flashcards

1
Q

Infliximab

A
  • anti-TNF (tumour necrosis factor)
  • used in rheumatoid arthritis and Crohn’s
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2
Q

Rituximab

A
  • Anti-CD20 (B cells)
  • used in non-Hodgkin’s lymphoma and rheumatoid arthritis
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3
Q

Cetuximab

A
  • epidermal growth factor receptor antagonist
  • used in metastatic colorectal cancer and head + neck cancer
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4
Q

Trastuzumab

A

HER2 receptor antagonist
- used in metastatic breast cancer

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5
Q

Alemtuzumab

A
  • anti-CD52
  • used in chronic lymphocytic leukaemia (CLL)
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6
Q

abciximab

A

glycoprotein IIb/IIIa receptor antagonist
- prevention of ischaemic events in patients undergoing PCI

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7
Q

OKT3

A
  • anti-CD3
  • used to prevent organ rejection
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8
Q

Other uses for monoclonal antibodies

A
  • medical imaging when combined with a radioisotope
  • identification of cell surface markers in biopsied tissue
  • diagnosis of viral infections
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MRCP Pharmacology (22 decks)

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