Monoclonal Antibody Indications Flashcards

(34 cards)

1
Q

keliximab indication

A

Rheumatoid arthritis

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2
Q

abciximab (Reopro)

A

Antithrombotic for PCI
prevention of MI

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3
Q

alemtuzumab (Lemtrada)

A

Chronic lymphocytic leukemia

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4
Q

apolizumab indication

A

Chronic lymphocytic leukemia

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5
Q

Basiliximab indication

A

Prevention of acute renal allograft rejection

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6
Q

Clenoliximab indication

A

Rheumatoid arthritis

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7
Q

Daclizumab indication

A

Prevention of acute renal allograft rejection

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8
Q

Edrecolomab indication

A

Adjuvant therapy for cancer

after colorectal surgery

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9
Q

Efalizumab indication

A

Treatment of severe plaque psoriasis

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10
Q

Enlimomab indication

A

Burns; stroke; prevention of acute rejection in renal transplant

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11
Q

Epratuzumab indication

A

Non-Hodgkin’s lymphoma

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12
Q

Gemtuzumab indication

A

CD33

positive acute myelogenous leukemia

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13
Q

Infliximab indication

A

Rheumatoid arthritis; ankylosing spondylitis; Crohn’s disease

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14
Q

Inolimomab indication

A

Prevention of graft rejection

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15
Q

Keliximab indication

A

Rheumatoid arthritis

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16
Q

Muromonab indication

A

Prevention of acute renal allograft rejection

17
Q

Natalizumab indication

A

Acute relapse in multiple sclerosis; Crohn’s disease

18
Q

Ocrelizumab (Ocrevus) indication

A

Multiple Sclerosis

19
Q

Odulimomab indication

A

Prevention of ischemic renal damage during kidney transplantation

20
Q

Omalizumab indication

A

Prevention of allergic asthma and seasonal rhinitis

21
Q

Palivizumab indication

A

Prevention of respiratory syncytial virus infection

22
Q

Visilizumab indication

A

Treatment of glucocorticoid-refractory acute graft-versus-host disease

23
Q

Rituximab, ofatumumab, obinutuzumab
indication

A

Hematologic malignancies

24
Q

Trastuzumab, Amivantamab, Nivolumab, Pembrolizumab indication

25
Adalimumab, Tocilizumab, Sarilumab indication
Autoimmune disorders
26
Evolucumab and Alirocumab indication
Hypercholesterolemia
27
Omalizumab indication
Asthma
28
Denosumab indication
Osteoporosis
29
Adalimumab, certolizumab pegol indication
Inflammatory bowel disease
30
Atoltivimab+maftivimab+odesivimab (Inmazeb), ansuvimab (Ebanga) indication
Ebola-specific therapies
31
Bezlotoxumab indication
Clostridioides difficile infection in adults
32
Idarucizumab (Praxbind) indication
Dabigatran reversal
33
Tixagevimab/cilgavimab (Evusheld) indication
COVID infection prevention in immunocompromised individuals who may not mount an adequate immune response to COVID-19 vaccination
34
Sotrovimab (Xeundy) indication
COVID. IV administration