Mood Disorder Flashcards

(74 cards)

1
Q

What is Masked Depression

A

Depressed mood not prominent, but other features of depression are

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2
Q

Define Mood

A

Patient’s sustained emotional state over a period of time

Can be Dysthymic (Low), Euthymic (Normal) or Elevated

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3
Q

Define Affect

A

Transient flow of emotion in response to a particular stimulus

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4
Q

Define Mood Disorder

A

Condition characterised by distorted/excessive/inappropriate moods for a sustained period of time

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5
Q

State the ICD10 class 1-7 for mood disorders

A

1 - Manic Episode (inc Hypomania)
2 - BPAD
3 - Depressive Episode
4 - Recurrent Depressive Episode
5 - Persistent Mood Disorders (Dysthymia, Cyclothymia)
6 - Other Mood Disorders
7 - Unspecified Mood Disorders

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6
Q

State the two classifications of Mood Disorder and give example

A

Unipolar - Depressive Disorders, Dysthymia

Bipolar - Cyclothymia, BPAD

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7
Q

State three causes of Secondary Mood Disorders

A

Physical Disorders (Hypothyroid, Cushing)

Psychiatric Disorders (Schizophrenia, Dementia)

Drug Induced

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8
Q

Define Depressive Disorder

A

Affective mood disorder characterised by persistent low mood, loss of pleasure and lack of energy

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9
Q

Give a Bio, Psycho, and Social PREDISPOSING factor for Depressive Disorder

A

Bio - Female
Psycho - Failure of effective stress control
Social - Lack of support

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10
Q

Other than the three core symptoms, give two cognitive symptoms of Depressive Disorder

A

Lack of conc. and decision making
Excessive guilt

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11
Q

Other than the three core symptoms, give two biological symptoms of Depressive Disorder

A

Diurnal Variation
Loss of Appetite

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12
Q

What is Becks Triad?

A

Negative thoughts about Self, World and Future

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13
Q

State the ICD10 classification of Mild, Moderate and Severe Depressive Disorder respectively

A

Mild - 2 core symptoms and 2 other symptoms
Mod - 2 core symptoms and 3-4 other symptoms
Severe - 3 core symptoms and >4 other symptoms

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14
Q

Name three diagnostic questionnaires for Depressive Disorder

A

PHQ9
HADS

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15
Q

Other than questionnaires, name two other investigations you could do for Depressive Disorder

A

Bloods (fbcs, tfts, glucose)

Head CT/MRI (sol)

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16
Q

What is Seasonal Affective Disorder?

A

Where mood is severely affected by change in seasons

Mood normally lowest in Winter months

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17
Q

What is Masked Depression

A

Depressed mood not prominent, but other features of depression are

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18
Q

What is Atypical Depression?

A

Presenting with the opposite of the typical features - such as Overeating and Hypersomnia

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19
Q

Define Dysthymia and Cyclothymia

A

Dysthymia - Depressive state for two years not meeting threshold

Cyclothymia - Chronic Mood Fluctuation for two years, insufficient to meet threshold

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20
Q

Give four non Pharmacological mainstay treatments of Depression

A

Self Help Programmes
CBT
Physical Activity Programmes
Psychotherapies

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21
Q

When would you use Antidepressants in Mild to Mod Depression?

A

Lasted a long time
History of Mod - Severe
Failure of other interventions

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22
Q

What is the first step in management of a Mod to Severe depressed patient?

A

Suicide risk assessment

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23
Q

When would you refer a Depressed patient to Psychiatry?

A

Suicide Risk High
Severe Depression
Recurrent Depression
Unresponsive to Initial Meds

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24
Q

Describe the pharmacological therapy of Mod to Severe Depression

A

SSRIs first line (continued for 5m after symptom resolution for first episode, reducing dose slowly in last month or 2y if second)

Adjuvants with Lithium or Antipsychotics

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25
Describe the non pharmacological management of Mod to Severe Depression
Psychotherapy (CBT, IPT) Social Support
26
When could ECT be recommended for a Depressed patient?
If acutely life threatening Depression with Psychotic Symptoms Severe Psychomotor Retardation
27
Define Bipolar Affective Disorder
Chronic episodic mood disorder characterised by at least one episode of Mania/Hypomania, followed by a further episode of Mania/Depression (Includes patients who at presentation have only suffered Mania as all will eventually develop depression)
28
What should you always screen for in a Depressed patient?
Mania
29
What is Hypomania?
Mildly elevated/irritable mood for present for at least four days Interruption of life but not disruption May have partial insight
30
Define Mania with Psychosis
Severely elevated mood with Hallucinations and Delusions
31
Bipolar 1 v 2
Bipolar I - Periods of severe mood episodes from Mania to Depression Bipolar II - Milder form of mood elevation, Hypomania alternating with Depression
32
Neologisms?
Creating new words
33
Three components of risk?
Others Self From others
34
What are the preferred SSRIs to treat depression?
Citalopram and fluoxetine
35
When is sertraline preferred over fluoxetine and citalopram?
Post MI
36
What is the most common Side effects of SSRIs
GI symptoms, increased risk of GI bleeds
37
How often should antidepressants be reviewed
2 weeks after start by a doctor 1 week if under 25
38
How long should patients be on antidepressants?
6 months after remission, reduced dose over 4 week period before it stops
39
What two types of GABA receptors are they
A & B
40
What ion does GABA receptors respond to and what ions influx to cause a reduce in membrane potential
GABA and chloride
41
How does benzodiazepines increase the effect of GABA
Increases the frequency of chloride channels
42
When are benzos used (5) ?
Sedation Hypnotic Anxiolytic Anticonvulsant Muscle relaxant
43
How long should benzos be prescribed for?
2-4 WKS
44
How do barbiturates affect gaba affects?
Increased durations of chloride channel opening
45
Frequently bend - during barbecue?
Frequency benzos - duration barbiturates
46
What can cause oculogyric crisis
Antipsychotics, its a form of acute dystonic reaction
47
Signs of acute dystonic reaction
Tongue protrusion, jaw spasm, unable to control gaze, fixed neck
48
Akathisia meaning?
Restlessness
49
Tardive dyskinesia meaning?
Typically involves the face and involves repetitive involuntary withdrawing movements (lip smacking, tongue protrusion and grimacing)
50
Parkinsonism meaning?
General term that mimics Parkinson’s disease (bradykinesia, cogwheel rigidity and shuffling gait)
51
Catatonia meaning?
Appear to be in stupor, maintain odd postures and appear awake but unresponsive to external stimuli
52
When can sodium valporate be used in relation to mental health
Epilepsy and bipolar
53
When is pregablin used
GAD and neuropathic pain
54
First line drug for schizophrenia
Olanzapine
55
When may Hypomania be seen
Type 2 bipolar affective
56
Epidemiology of bipolar?
2% prevalence, develops late teens
57
What are the differences between the bipolar disorders
Type 1 - depression and mania Type 2 - Hypomania and depression
58
First line treatments for bipolar (3)?
Psychological interventions, lithium and valproate
59
How to manage bipolar
Manage mania/Hypomania - stopping antidepressants, antipsychotic therapy Depression - talking therapies, fluoxetine Co-morbidities - 2-3x increased risk of diabetes, CVD
60
What does HAD scale consist of?
14 questions (7 for anxiety, 7 for depression)
61
How does HAD work and scoring
Each item is scored 0-3 produces a score of 21 for both anxiety and depression. 0-7 = normal, 8-10=borderline, 11+ case
62
PHQ-9 scale explained?
9 items scored 0-3, items can include thoughts of self-harm. 0-4 none, 5-9 mild, 10-14 moderate, 15-19 moderately severe, 20-27 severe
63
What criteria does nice use
DSM-IV
64
How many symptoms are required to diagnose depression?
5/9
65
9 diagnostic tools of depression?
1 - depressed mood nearly every day/most of the day 2 - anhedonia 3 - weight loss or weight gain 4 - insomnia/hypersomnia 5 - psychomotor agitation or retardation every day 6 - fatigue or loss of energy 7 - worthlessness or guilt 8 - diminished conc./indecisiveness 9 - recurrent thoughts of death, suicidal ideation
66
Pseudohallucinations are ?
Vivid enough to be hallucinations but subjective and unreal they are a symptoms of PTSD
67
Repression vs suppression
Suppression = intentional and temporary withholding an idea or feeling from= conscious awareness Repression = involuntary withholding
68
What type of drug is amitriptyline
TCA - tricyclic antidepressant
69
MOA of TCAs
Inhibit the uptake of monoamine at the presynaptic membrane - bind to the ATPase monoamine pump within the presynaptic membrane
70
Splitting is?
Believing that people are either all good or all bad
71
Fixation is?
Remaining in a more childish level of development
72
Sublimation meaning?
Channeling unacceptable thoughts into socially acceptable alternatives
73
How does bipolar differ to BPD?
BPD is fluctuating moods over hours whereas bipolar the mania can last 7 days+ and hypomania 4 days+
74