More Pharm

Question 1

How does a pop work

Answer 1

Thickens cervical mucousa

Question 2

Common side effects of oral theophylline

Answer 2

High rate of adverse side effects

CNS: Agitation and insomnia, Headaches, seizures
Can cause peptic ulcer disease
Can cauase HYPOkalaemia

Question 3

Cranberry Juice affects which drug

Answer 3

Warfarin

Question 4

What does it do to warfarin

Answer 4

Increases INR so inhibits breakdown

Question 5

What are treatments of Pulmonary Hypertension

Answer 5

Endothelin A and B antagonists- Bosentan

Endothelin A antagonist alone- Ambrisentan- A for ambrisentan

Question 6

Risperidone main receptor actions

Answer 6

Against D2 an 5HT2 receptors

Question 7

Drugs which can cause a raised anion gap acidosis include

Answer 7

Ethanol
Metformin
Methanol
Aspirin

Emma Stone was Gwen stacey who often worked with acids as a scientist

Question 8

Side effects of Vincristine

Answer 8

Peripheral neuropathy

SIADH

Question 9

Side effects of Cyclophosphamide

Answer 9

Haemorraghic cystits

Question 10

Side effects of Bleomycin

Answer 10

Interstitial pneumonia

Question 11

Side effects of Doxorubicin

Answer 11

Cardiomyopathy

Question 12

Effect of Nicorandil

Answer 12

Potassium channel activator
So causes relaxation of smooth muscle in veins
- less preload on heart less exertion.

Because it dilates blood bessels to brain it can often cause headaches (1/3rd of patients)

Can also cause non healing oral ulcers

Question 13

What drug do you need to alter concentration if patient stops smoking

Answer 13

THeophylline

Question 14

What can increase the chances of gettign gout episodes

Answer 14

treatign with thiazide diuretics

Help with renal stones dont help with gout. Reduce urate excretion which builds up in the body

Question 15

Examples of GABA-t inhibitors

Answer 15

Valproate and vigabatrine

Question 16

Glutamate inhibitors

Answer 16

Topiramate

Question 17

What do benzodiazepines and barbiturates do

Answer 17

GABA a agonist binding at specific sites

Question 18

Na channel blocker

Answer 18

Phenytoin and Carbamazepine

Question 19

Foods to avoid with MAO inhibitors

Answer 19

Red wine
Dairy- Cheese and Milk
Broad beans
Marmite

Question 20

What is a GABA B agonist?

Answer 20

Baclofen

Question 21

What increases insulin releases in short amounts so you take it before meals

Answer 21

Meglitinides

Question 22

Cisplatin side effects

Answer 22

Causes nephrotoxicity in 30% of patients

Question 23

Mechanism of Clopidogrel

Answer 23

ADP receptor inhibitor on platelets so platelets dnt get activator

Question 24

Mechanism of Dipyridamole

Answer 24

Inhibits Phosphodiesterase inhibitor
increases cAMP
Inhibit platelet aggretation

Question 25

How does carbimazole work

Answer 25

Inhibits the ionidnation of tyrosine the first step in production of thyroxine