Movement Disorders Flashcards
(17 cards)
What are the treatments for Essential Tremor?
Propranolol, primidone, topiramate
What are the treatments for Huntington Disease?
Symptomatic — valbenazine, tetrabenazine, deutetrabenazine
What causes Drug-Induced Dystonia (Tardive Dyskinesia)?
- Antipsychotics
- Antiemetics
- Antidepressants
What are the treatments for Drug-Induced Dystonia (Tardive Dyskinesia)?
Stop offending agent + valbenazine, deutetrabenazine, amantadine, clonazepam
What are the treatments for Cervical Dystonia (Torticollis)?
- Botulinum toxin injections
- Anticholinergics
- Benzodiazepines
- Baclofen, levodopa
What are the treatments for Tourette Syndrome?
- Reassurance
- CBT
- Meds if severe (not listed here but typically Antipsychotics or Alpha-2 agonists)
What are the key features of Myoclonus?
Rapid, shock-like jerks of isolated muscles
Screen patients <40 years with “essential tremor” or dystonia for ?
Wilson disease with Serum Ceruloplasmin and 24-hour urine copper measurements.
What are the presenting symptoms of cauda equina syndrome?
Severe unilateral pain in the saddle region, radiating down to the legs, lower-extremity weakness
Significant bowel/bladder/sphincter symptoms distinguish it from Guillain-Barré syndrome.
How does cauda equina syndrome differ from Guillain-Barré syndrome?
Significant bowel/bladder/sphincter symptoms
GBS does not present with these symptoms.
What are the characteristics of transverse myelitis (TM)?
Can mimic GBS in spinal shock, but GBS lacks bowel/bladder symptoms and sensory loss below a spinal cord segment
Understanding these differences is crucial for diagnosis.
What symptoms characterize Spinal Cord infarction?
Abrupt onset of back pain, weakness, loss of sensation and reflexes, autonomic dysfunction
The onset of symptoms and antecedent viral illness suggest TM.
What is the effect of vitamin B12 deficiency?
Slowly progressive weakness, ataxia, neuropsychiatric disturbances
Acute onset of symptoms is less consistent with cobalamin deficiency.
What does MRI with contrast show in cases of Transverse Myelitis?
Enhancing cord segments with surrounding edema
This imaging finding is important for diagnosis.
Spinal Cord Infarction
Cauda Equina Syndrome
Transverse Myelitis