mroeeee stuff Flashcards

1
Q

membrane

A

separates extracellular environment from intracellular

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2
Q

membrane allows for what to develop

A

gradients

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3
Q

membrane property

A

semi permeable barrier

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4
Q

membrane composition

A

asymmetrical environment
an association of phospholipids, and protiens

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5
Q

what type of amino acid typically bypasses the bilayer

A

hydrophobic

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6
Q

what do phospolipids spontaneously form

A

liposomes and bilayers

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7
Q

why are membranes energetically favorable

A

hydrophobic effect

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8
Q

inner leaflet

A

negative charge bc serine in
Phosphatidylserine and phosphatidylinositol

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9
Q

outter leaflet/ extracell leaflet features

A

Neutral/ positive
mostly glycolipids

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10
Q

bc of charge of membrane

A

membranes contribute a lot to migration of ions

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11
Q

membrane permeability what passes thru easy

A

small polar molecules

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12
Q

membrane permeability what passes thru easyish

A

small uncharged polar molecules

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13
Q

membrane permeability what passes thru harder

A

large macromolecules

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14
Q

membrane permeability what passes thru HARD

A

ions

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15
Q

membrane permeability is enhanced by

A

transporter and channel protein embeded in membrane

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16
Q

scramblases and flipase

A

speeds up the rate of smth flipping across membrane

17
Q

where are phosolipdis synthesized

A

in the cytomatic side of ER

18
Q

scramblases

A

move phospholipids to the cytosolic and lumen leaflets

19
Q

flippases

A

at golgi
separates specific types of phosphlipids to the cytosolic and lumen leaflets

20
Q

chemical changes to phosopholipid to make it more fluid

A

add double bond or make it sat

21
Q

Cholesterol

A

fluidity buffer in animal cells
at low temps, increases fluidity by reducing fatty acid interactions

22
Q

cholesterol at high temp

A

increases to fill in gaps from phospholipids moving too much
maintains fluidity

23
Q

lipid rafts

A

fatty acid chain that increases the thickness of the membrane in certain regions

24
Q

lipid rafts are home to

A

proteins involved in signaling or trafficking

25
FRAP
flouresncene recovery after photobleaching
26
protien funciton in membrane
enzymes, repectors, transporters, channels, anchors
27
receptor
binds to molecules that activate the recpetor, intracellualr signal
28
transporters/channels
move molecules from one side to another
29
anchors
attach to proteins on other cells and hold them together attache to extracellular matrix attach to intracellular cytoskeleton
30
protien associate with membrane thru
hydrophobic interactions amphipathic helices
31
peripheral membrane protien
can release from membrane
32
how many amino acids to span a layer
20
33
aquaporin
alpha helix based channel protein that forms a pore (7)
34
extracellular regions usally have
disulfide bonds
35
extracellualr regions usally have - attached
carbos glycoprotiens