protiens Flashcards

(36 cards)

1
Q

proteins are made of

A

amino acids

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2
Q

amino acid parts

A

amino group
carboxyl
single hydrogen
r group

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3
Q

amino acids are linked through

A

peptide bonds

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4
Q

n terminal

A

first amino acid in sequence

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5
Q

c terminal

A

last amino acid in sequence

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6
Q

protein shapes are due to

A

ionic bonds
hydrophobic bonds
hydrogen bonds
disulfide (cystine only)

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7
Q

primary protein structure

A

amino acid sequencese

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8
Q

secondary struc

A

interactions of gorup in peptide backbone

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9
Q

tertiary structure

A

folded shape of single polypeptide chain

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10
Q

quaternary structure

A

interactions bn multiple polypeptide subunits

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11
Q

secondary structure motifs

A

alpha helix
beta sheet

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12
Q

alpha helices

A

twisty i guess

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13
Q

beta sheets

A

antiparrallel
parallel

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14
Q

function determines

A

folding pattern

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15
Q

enzyme folding creates

A

activation sites

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16
Q

enzyme role

A

lower actvation energy for a reaction by binding to active site

17
Q

domain

A

independent folding region
more than 2nd, less than tertiary
like packets of structure

18
Q

how do proteins/ polypeptides interact

A

with h bonds, ionic bonds, and hydrophobic

19
Q

types of protein/ polypeptide interactions

A

surface surface
helix helix
surface string

20
Q

x ray crystallography

A

need protein crystal for the process
needs diffraction patter

21
Q

protein nmr

A

gets solution based structures
creates resonance peaks bn near neighbor atoms

22
Q

cryo EM

A

generate micorgrapahs of a protein
structure get resolved by computer refinements

23
Q

Alpha fold

A

ai protein structure generator
its accurate asf

24
Q

denaturation

A

protein structure melts and funciton is lost

25
denaturation can be caused by
pH, temp, salt, hydration
26
nucelotides
make up of nucleic acids such as DNA and RNA
27
nucleotide fucntion
storgage, transmission, used of genetic info
28
nucleotide units
sugar, phosphate, base
29
nucelotides are linked with
phosphodiester bonds
30
polynucleotide strands are (orientation)
antiparallel and complementary
31
what forces hold ds DNA together
h bonds (base pairings) hydrophobic forces (base stacking)
32
RNA
less stable than DNA usaly one stranded
33
mRNA
provides codons for amino acid to be added to polypeptide
34
tRNA
carries an amino acid that corresponds to the ribosome
35
rRNA
part of the structure of the ribosome
36