MS Flashcards

1
Q

Other name for Neuroglia?

A

Glial Cells

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2
Q

What is the purpose of neuroglia?

A

Supports the nerve cell/neuron

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3
Q

What type of cell is neuroglia?

A

non-excitable

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4
Q

it is the WBC in the CNS that functions as defence to infection et injury

A

Macrophage

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5
Q

Form et maintain myelin sheath in the CNS

A

Oligodendrocytes

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6
Q

If the PNS is affected, what structure is affected?

A

Schwann cell

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7
Q

a star-shaped cell that has the most numerous

A

Astrocytes

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8
Q

What are the functions of astrocytes?

A

Provide structural support to the CNS, take up extracellular K ions, glycogen storage, capable of cell mulitiplication, regulate extracellular concentration of the neurotransmitter

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9
Q

It assist in the circulation of CSF and it is located in the ventricles et central canal of the SC

A

Ependymal Cells

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10
Q

Form the myelin sheath

A

Schwann Cell

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11
Q

Act as protective, cushioning cells for peripheral neuron cell bodies

A

Satellite Cells

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12
Q

Other name for MS?

A

Great Crippler of Young Adults

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13
Q

what are the Charcot’s Triad?

A

S- scanning speech
I- intention Tremor
N- nystagmus

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14
Q

demyelination areas eventually become filled of fibrous astrocytes and undergo a process called ____

A

Gliosis

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15
Q

What is the hallmark of MS?

A

Glial Scar

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16
Q

What are the sites of pre-dilection?

A
P- preventriccular White Matter
C- Corticospinal Tract
C- Cerebellar Penducle
O- Optic Nerve
P- Posterior White Column of the Spinal Cord
17
Q

it is a type of MS that remains fully functional in all neurological system 15 years after onset

18
Q

It is a type of MS that has rapid onset and almost continual progression

A

Malignant MS

19
Q

What is the other term for Malignant MS?

A

Marburg’s Disease/ Variant

20
Q

Pseudo exacerbation of Sx

A

Uthoff’s Phenomenon

21
Q

what happens when a pt c MS is exposed to heat or warmth?

A

pt will feel fatigue

22
Q

What is the gold standard Dx tool for MS?

23
Q

characterized by discrete attacks of neurological deficits with either full/ partial recovery in subsequent to months

A

Relapsing Remitting MS (RRMS)

24
Q

Has the highest case type of MS?

25
Characterized by initial relapsing-remitting course with progression to steady and irreversible decline with or without continued acute attacks
Secondary Progressive MS (SPMS)
26
It the adverse effect of RRMS
SPMS
27
Characterized by nearly continuous worsening of the disease from onset without disk attack
Primary Progressive MS (PPMS)
28
A major type of MS that is associated later onset and happens at 10% of cases
PPMS
29
Characterized by steadt deterioration dsease but occasional acute attacks; 5% of cases
Progressive Relapsing MS (PRMS)
30
This drug is used to slow down the progression of MS
Interferon Meta Drugs
31
What are some examples of Interferon Meta Drugs?
- Betaferon - Extavia - Plegridy - Avonex - Rebif
32
This drug is used for acute flare-ups and it shortens the episode of MS
Immunosuppressive Drugs
33
What are some examples of immunosuppressive durgs?
- Dexamethasone | - Predisone
34
What are some examples of anti-spasticity drugs?
- Dantrolene (CNS) | - Baaclofen (SCI)
35
With drug is used for MS pts with urinary problems
Anticholinergic Drugs
36
Valid too to evaluate and measure MS pts level of functioning
Kurtzke Expanded Disabiity Status Scale (KEDDS)
37
What are the functional system of KEDSS?
``` V- visual system S- sensory system P- pyramidal system B-brainstem system B- bowl et bladder system M- mental status C- cerebellar system ```