MSK Flashcards
Describe the approach to MSK x-rays
- IPADS:
- Information
- Patient details
- Radiograph date, view, adequacy (RIP)
- Pattern of fracture - transverse/oblique/comminuted
- Anatomy
- Location on bone
- Intra/extra articular
- Distal fragment
- Displaced/angulated/rotated/impacted
- Soft tissues - disruption/swelling/foreign bodies
Describe the different types of fracture pattern

What are the terms used to describe displacement?
- Angulation
- Translation
- Shortening
- Rotation

How is the site of fracture described?
- Diaphyseal (shaft)
- Metaphyseal (ossification plate)
- Intra/extra articular
- Junctional

What is osteoarthritis?
Non-inflammatory degenerative joint disease characterised by loss of cartilage at synovial joints with degeneration of the underlying bone
- Commonly affects DIP joints, thumb MCP, cervical and lumbar spine, knee, hip
Name some clinical features of osteoarthritis
- Joint pain and stiffness
- Worse at end of day/after activity
- Can be nocturnal
- Joint instability
- Loss of joint function / limited range of movements
- Synovitis
- Crepitus
- Nodes
- Herberdens (DIP) - outer Hebrides
- Bouchard’s (PIP)
- Squaring of the hand (CMC prominence)
What x-ray changes are seen in osteoarthritis?
LOSS
- Loss of joint space
- Osteophyte formation
- Subchondral bone sclerosis
- Subchondral cyst formation
How is osteoarthritis managed?
- Pain relief - paracetemol / NSAIDs (+/- omeprazole)
- Weight loss if BMI > 28
- Walking aids
- Supportive footwear
- Physiotherapy / hydrotherapy
- Steroid/LA injections (= 2 times a year)
- Surgery
Why is surgery indicated in osteoarthritis?
- Pain not controlled by medication
- To improve mobility
- Correcting deformities
What is osteoporosis?
Skeletal disorder characterised by decreased bone mass and increased risk of fractures due to deterioration of the microarchitecture of bone tissue.
Name some primary causes of osteoporosis
- Age
- White/asian
- Female
- Early menopause
- Family history
- Low calcium / vitamin D
- Smoking / alcohol
Name some secondary causes of osteoporosis
- Hyperthyroid / parathyroid
- Hypogonadism
- Cushings
- RA
- IBD
- Renal failure
- Drugs - steroids, heparin, anti-convulsants
How is osteoporosis diagnosed?
- DEXA scan to measure bone mineral density
- BMD expressed as aT score (number of SDs away from mean)
- Osteoporosis < -2.5
- X-ray
- Investigations into secondary cause
- FBC
- ESR
- Serum calcium
- ALP
- TSH
How is osteoporosis managed/prevented?
- Calcium rich diet
- Stop smoking
- Increase weight-bearing exercise
- Bisphosphonate (alendronic acid 10mg/ didronel)
- Inhibit osteoclast activity
- Vitamin D supplement
- HRT in women / SERM (raloxifene)
- Calcitonin
How can falls be prevented in osteoporosis?
- Mobility device
- Avoidance of sedatives or hypotensive drugs
- Removal of obstacles in the home
- Ensure co-morbidity is treated
- Eyesight
- Syncope
- Cardiac arrhythmia
- OA/RA
What is Paget’s disease / osteitis deformans?
Increased bone turnover associated with increased numbers of osteoclasts and osteoblasts with resultant remodelling, bone enlargement, deformity and weakness
- Autosomal dominant
- Common sites are spine, skull, pelvis, femur, tibia
Name some clinical signs/complications of Paget’s disease?
- Deafness (bone overgrowth)
- Cranial nerve palsies
- Cardiac hypertrophy / high output CCF
- Spinal stenosis / spinal nerve entrapment
- Secondary OA
- Pathological fractures / osteosarcoma
- Bowing of tibia
How is Pagets investigated?
- ALP (raised)
- Normal serum calcium and phosphate
- X-ray - sclerosis and osteoporosis
- Isotope bone scan = areas of focal increased uptake (hot spots)
- High urinary excretion of hydroxyproline
How is Pagets managed?
- Pain relief
- Manage fractures appropriately
- Drugs that reduce bone turnover such as calcitonin or bisphosphonates
- Surgical treatment for fracture, deformity or sarcoma
What is osteomalacia?
Low mineral content but normal amount of bone
- Osteomalacia after fusion of epiphyses
- Rickets during bone growth
Name some causes of osteomalacia
- Vitamin D deficiency
- Malabsorption
- Poor diet
- Lack of sunlight
- Renal failure
- Drug-induced
- Anti-convulsants (induce liver enymes)
- Genetic vitamin D resistance
- Liver disease = decreased production/malabsorption
Name some signs and symptoms of rickets/osteomalacia
Rickets:
- Valgus deformity
- Bow-legged
- Hypocalcaemia
Osteomalacia:
- Bone pain
- Fractures (NOF)
- Proximal myopathy (waddling)
How is osteomalacia investigated?
- Bloods - dec calcium, phosphate, vit D, inc ALP, PTH
- Biopsy - incomplete mineralisation
- X-ray
- Loss of cortical bone
- Loosers zone = wide, transverse lucencies at right angles to cortical bone (pseudofracture)
- Blurred trabeculae
How is osteomalacia managed?
- Treat underlying cause
- Vitamin D supplements (calciferol)
- 400 units
































