MSK Flashcards
What would symmetrical small joint swelling suggest?
Rheumatoid arthritis
Name the categories of inflammatory arthritis?
Seropositive
Seronegative
Infectious
Crystal induced
Name the seropositive arthritis?
RA Lupus Sclerodema Vasculitis Sjorgens
Name the seronegative arthritis?
Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
Inflammatory bowel disease arthritis
What is the ‘S factor’?
Stiffness
Swelling
Squeezing is painful = an inflammatory arthritis
How do we diagnose RA?
History and clinical exam
Inflammatory markers (CRP,plasma viscosity)
Autoantibodies
Imaging
Which auto-antibody is most specific for RA?
Anti-CCP antibody
Treatment for RA?
Early recognition and diagnosis
Early treatment with DMARDS
Tight control with target of remission Patient education
What is the description of uric acid crystals as seen under polarised light microscopy?
Negatively birefringent, needle shaped crystals
2 main crystal arthropathies?
Gout Pseudogout (Calcium pyrophosphate deposition disease)
How does gout present?
Intense pain, redness and swelling
How do CPPD uric acid crystals appear?
Rhomboid shaped and weakly positive birefringent
Name key features of OA on X-ray?
Loss of joint space Osteophyte formation Subchondral sclerosis Subchondral cysts - remember LOSS
Which type of arthritis has periarticular erosions?
RA
In a patient with fibromyalgia, what blood abnormalities would you expect to see?
No abnormality
Would morphine sulfate be a suitable treatment for fibromyalgia?
NO
Treatment for fibromyalgia?
Use atypical analgesics (amitriptyline, gabapentin) Graded exercise programmes CBT Paracetamol NOT STEROIDS
What can precipitate fibromyalgia?
Emotional or physical trauma
Best investigation when you suspect septic arthritis?
Synovial fluid analysis and culture
Symptoms of septic arthritis?
Often a normal joint with previous trauma.
Fever, erythema, warm affected joint. Decreased range fo motion, severe pain when bearing weight
What is carpal tunnel syndrome caused by?
Compression of the median nerve as it travels under the flexor retinaculum
Why does pregnancy predispose to Carpal Tunnel Syndrome?
Increased oedema causes a narrowing of the carpal tunnel, predisposing entrapment of the median nevrve
Symptoms of carpal tunnel syndrome?
Numbness, paresthesia in median nerve distribution (thumb, index, middle and radial half of ring finger)
Treatment of CTS?
Splint the wrist or local corticosteroids