MSK n Rheums Flashcards

(40 cards)

1
Q

What is the most common causative organism of Discitis?

A

Staph aureus

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2
Q

If Discitis caused by Staph aureus, what investigation tells you the most likely cause?

A

Echo, bc probs caused by Inf endocarditis

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3
Q

What is the Dx when pt has Proximal muscle weakness + raised CK and NO rash?

A

Polymyositis

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4
Q

What are the CF of Polymyositis? (5 things)

A
  1. Proximal muscle weakness
  2. Raised CK
  3. Raynauds
  4. Resp muscle weakness
  5. No rash
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5
Q

What will be raised in Polymyositis? (2 things)

A
  1. CK
  2. Anti-synthetase antibodies
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6
Q

What is the Mx for Polymyositis?

A

High dose corticosteroids

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7
Q

What is the Mx for Polymyositis?

A

High dose corticosteroids

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8
Q

What will you see on joint aspiration of pseudogout?

A

Calcium pyrophosphate dihydrate crystals

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9
Q

What causes Pseudogout?

A

Hyperparathyroidism

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10
Q

What is the Mx for Pseudogout? (2 things)

A
  1. NSAIDs
  2. Steroids
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11
Q

What is a resp side fx of MTX?

A

Pneumonitis (dry cough, SOB, fever)

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12
Q

What drug does Allopurinol have a severe interaction with?

A

Azathioprine –> bone marrow suppression

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13
Q

What is the MAO of Allopurinol?

A

Xanthine oxidase inhibitor

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14
Q

What is a special test you can do when you sus of Ankylosing Spondylitis?

A

Schobers test

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15
Q

What are the CF of Ankylosing Spondylitis in Schobers test? (3 things)

A
  1. Reduced chest expansion
  2. Reduced lateral flexion of spine
  3. Reduced forward flexion
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16
Q

What are some assoc CF of Ankylosing Spondylitis? (4 things)

A

All the A’s:
1. Ant uveitis (painful / blurry vision)
2. Aortic Regurg
3. Apical fibrosis
4. Achilles tendonitis (heel pain)

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17
Q

What is the antibody in Antiphospholipid syndrome?

A

Anti-cardiolipin

18
Q

What is a common cause of BILATERAL carpal tunnel syndrome?

19
Q

If pain in a Rib # is not controlled by normal analgesia, what can you consider?

A

Intercostal nerve block

20
Q

What is Psoriatic arthritis assoc with?

A

Psoriasis of skin

21
Q

What antibody is Psoriatic arthritis assoc with?

22
Q

What are the CF of Psoriatic arthritis? (4 things)

A
  1. Symmetrical / asymmetrical arthritis (symmetrical more common tho)
  2. Sausage fingers
  3. Psoriatic skin
  4. Sacroiliitis
23
Q

What are the CF of Dermatomyositis? (3 things)

A
  1. Symmetrical proximal muscle weakness
  2. Macular rash on back + shoulders
  3. Gottrons papules (rough red things on fingers)
24
Q

What do you need to screen for after Dx of Dermatomyositis?

A

Malignancy
(bc assoc w underlying cancer)

25
What are the antibodies in Dermatomyositis? (3 things)
1. ANA 2. Jo1 3. anti-Mi-2 Ana, Jo, wa Me
26
What are the CF of Polymyalgia rheumatica? (5 things)
1. Old pt (60+) 2. Rapid onset (less than 1 month) 3. Morning stiffness 4. NO WEAKNESS (strength no weakness innit) 5. Mild polyarthralgia
27
What are the investigation results for Polymyalgia rheumatica? (2 things)
1. Raised ESR 2. NORMAL CK
28
What is the Tx for Polymyalgia rheumatica?
Prednisolone
29
What drugs can cause drug induced lupus? (4 things)
1. Procainamide 2. Hydralazine 3. Isoniazid 4. Phenytoin
30
What are the CF of Drug induced lupus? (4 things)
1. Arthralgia 2. Myalgia 3. Malar rush 4. Pleurisy
31
What are the antibodies in Drug induced lupus? (2 things)
1. ANA 2. Anti-histone
32
What are the CF of Reactive Arthritis? (4 things)
Arthritis (asymmetrical) + Can’t see, pee, or climb a tree 1. SEE = Conjunctivitis / Ant Uveitis 2. PEE = Urethritis 3. CLIMB TREE = waxy brown papules on palm + soles
33
Can you recover the causative organism of Reactive arthritis from the joint?
No
34
How long after the initial infection do you get Reactive arthritis?
4 weeks
35
What movement is impaired in Adhesive capsulitis?
External rotation (both active + passive)
36
What are the RF for Adhesive capsulitis? (4 things)
1. Female 2. 40-70 yrs 3. DM 4. Hypothyroidism
37
What should you give in MTX toxicity?
Folinic acid
38
What is the best way to Dx Ankylosing Spondylitis?
Pelvic XR (will see sacro-ilitis)
39
What abx can you not give with MTX?
Trimethoprim (methoTRexate + TRimethroprim)
40
Why cant you give methoTRexate + TRimethroprim together?
Risk of bone marrow suppresion