MSK/Rheumatology - RA, OA - Exam 3 Flashcards

(29 cards)

1
Q

External trigger (ex: smoking) > Autoimmune + Inflammatory response > synovial hypertrophi + joint inflammation > Destruction of joints > Joint deformity is the progression of what disease?

A

Rheumatoid arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What inflammatory disease is characterized by symmetrical polyarthritis that progresses from periphery to proximal and has improvement with movement?

A

Rheumatoid arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How can Rheumatoid arthritis present in the hand?

A

Affects MCP and PIP joints
Spares DIP joints
Swan neck and boutonniere deformaties
Ulnar deviation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How can Rheumatoid arthritis present in the upper extremities?

A

Carpal tunnel
Frozen shoulder
Rheumatoid nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How can Rheumatoid arthritis present in the lower extremities?

A

Affects MTP joints on the feet

Popliteal (bakers cyst)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What part of the axial skeleton can rheumatoid arthritis affect t?

A

Cervical spine C1-C2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How does rheumatoid arthritis affect the cervical spine?

A

Cerval subluxation

Cervical myelopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is seen in the lab results of person with rheumatoid arthritis?

A

Rheumatoid factor (RF)
ant-CCP antibodies
ANA ~30% of patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What pharmacological agent is given to all patients dx with rheumatoid arthritis?

A

DMARDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How long does morning stiffness last with rheumatoid arthritis?

A

More than 1 hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the characteristics of the joints with rheumatoid arthritis?

A

Soft, warm, tender

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Does RA or OA have more extraarticular manifestations?

A

RA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What degenerative disease is characterized by joint pain stiffness and functional impairment of all joint tissues and has improvement with rest?

A

Oesteoarthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How can osteoarthritis present in the hand?

A

Affects the MCP, PIP, and DIP joints
Heberden’s nodes
Bouchard’s nodes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How can osteoarthritis present in the lower extremities?

A

Most common in knees and hip
Swelling
Restricted ROM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How long does morning stiffness last with osteoarthritis?

A

Less than 30min

17
Q

What are the characteristics of the joints with osteoarthritis?

A

Hard and bony

18
Q

How is osteoarthritis diagnosed?

A

Clinical
Weight baring imaging
No definitive lab tests

19
Q

How is rheumatoid arthristis diagnosed?

A

ACR/EULAR criteria

1 joint with definitive clinical synovitis

20
Q

What is the treatment for osteoarthritis?

A

Treat pain and inflammation

Surgery if conservative tx fails

21
Q

What inflammatory disease is characterized by proximal aching and stiffness associated
with giant cell temporal arteritis?

A

Polymyalgia Rheumatica

22
Q

How long does morning stiffness last with polymyalgia rheumatica?

A

More than 1 hr

23
Q

Symptoms of PMR are due to what?

A

Synovitis, tenosynovitis, and bursitis

24
Q

Where are the most common locations of pain with polymyalgia rheumatica?

A

Shoulder and pelvic girdle

Difficulty brushing hair or rising from a chair

25
How does polymyalgia rheumatica affect the shoulders?
Restricted ROM Pain Normal muscle strength
26
How is polymyalgia rheumatica diagnosed?
No established criteria Elevated ESR Rapid resolution with glucocorticoids
27
What inflammatory disease is characterized by widespread pain lasting for more than 3 months, extreme fatigue, cognitive disturbances with an absence of joint swelling/inflammation?
Fibromyalgia
28
What are the nonpharmacological treatment option for Fibromyalgia?
Exercise PT Cognitive behavioral therapy
29
What are the pharmacological treatment options for Fibromyalgia?
Tricyclic antidepressant SNRIs- Duloxetine, Milnacipran Anticonvulsants- Pregabalin, Gabapentin