MT2 Goals

Question 0

Osteomyelitis

Answer 0

Eradicate the infecting organism, thus decreasing morbidity (early antibiotic therapy may decrease the need for surgical debridement)
Prevent long term sequelae through effective treatment of infection
Provide cost effective, convenient therapy

Question 1

Skin and soft tissue infections

Answer 1

Prevent mortality
Eradicate the infecting organism
Minimize/prevent morbidity (osteomyelitis, amputation, sepsis)
Minimize signs and symptoms
Minimize ADRs to therapy

Question 2

Septic arthritis

Answer 2

Eradicate the infecting organism, thus decreasing morbidity and mortality (early abx therapy plus joint drainage and joint rest are pivotal)
Prevent long term sequelae through effective treatment of the infection
Provide cost effective convenient therapy

Question 3

Bacterial endocarditis

Answer 3

Eradicate the infecting organism with appropriate therapy
Decrease signs and symptoms of the disease within one week
Decrease morbidity
Minimize impact of adverse events of drug therapy by providing appropriate therapy for appropriate period of time
Prevent infective endocarditis from occurring or recurring in high risk populations with appropriate prophylactic antimicrobials

Question 4

Bacterial meningitis

Answer 4

Eradicate the infecting organism
See a decrease in signs and symptoms of the disease, especially within the first 24-72 hours
Provide effective drug therapy that decreases the chance of neurological sequela
Minimize the impact of adverse effects by educating health care professionals and care providers about the potential adverse effects

Question 5

Malaria

Answer 5

Prevent mortality
Eliminate the infection within 48-72 hours
Minimize morbidity (hypoglycemia, pulmonary edema, and renal failure)
Minimize symptoms
Prevent malaria in those at risk
Minimize adverse drug reactions
Provide cost effective therapy

Question 6

Amebiasis and Giardia

Answer 6

Cure infection by elimination of parasite
Prevent morbidity (organ abscess)
Minimize symptoms (mostly GI)
Minimize adverse drug reactions
Provide cost effective therapy