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Autonomics > Muscarinic antagonists > Flashcards

Muscarinic antagonists Flashcards

1
Q

what effect do muscarinic antagonists have on the eye?

A

mydriasis (dilation) of pupil

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2
Q

what effect do muscarinic antagonists have on the heart?

A

allow HR to increase (not by any means of stimulation)

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3
Q

what effect do muscarinic antagonists have on the bladder?

A

constriction

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4
Q

what effect do muscarinic antagonists have on the glands?

A

prevent secretion

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5
Q

what effect do muscarinic antagonists have on the lungs?

what would you expect they would be a treatment for?

A

prevent bronchoconstriction

asthma and COPD

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6
Q

what effect do muscarinic antagonists have on the GI tract?

A

slow down gut

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7
Q

what effect do muscarinic antagonists have on the CNS?

A

block muscarinic receptors in brain

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8
Q

What effect does atropine have at low doses?

A

Dry mouth and thirst, dry skin, increased HR

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9
Q

What effect does atropine have at medium doses?

A

Mydriasis, blurred vision, tachycardia

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10
Q

What effect does atropine have at high doses?

A

Rapid, weak pulse and CNS effects

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11
Q

Atropine may dilate the pupil for? (days)

A

7-10 days

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12
Q

What are the uses of Atropine?

A

Cardiac stimulant
Anti-diarrheal
Treat mushroom and nerve gas poisoning

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13
Q

what was Hyoscyamine used for?

A

irritable bowel syndrome, incontinence, hyperhidrosis, peptic ulcers

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14
Q

what is Scopolamine used for?

A

motion sickness

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15
Q

what is Ipratropium used for?

A

rhinorrhea

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16
Q

You would expect Tiotropium, Glycopyrrolate, Formoterol, Aclidinium bromide, and Umeclidium to target M1 or M2 receptors?
what do they reduce in lungs?
would you expect a lot of systemic side effects?

A

M1 receptors
lung secretions
no

17
Q

Fesoterodine, Tolterodine, Oxybutynin, Trospium, Solifenacin succinate, and Darifenacin are used to treat?
side effects?

A

incontinency and
overactive bladder syndromes
SE: dryness and constipation

18
Q

what is tropicamide used for?

A

eye exams

19
Q

what is glycopyrrolate used for?

A

control drooling and hyperhidrosis (excessive sweating)

20
Q

what are benztropine and biperiden used for?

A

drug-induced parkinsons

Autonomics (14 decks)

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