Muscle Ultratissue Flashcards

(32 cards)

1
Q

Types of muscle

A

Skeletal, cardiac, smooth

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2
Q

Skeletal muscle is…

A

Striated muscle which is under voluntary control of the somatic nervous system

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3
Q

Cardiac muscle is

A

Striated muscle found only on the heart

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4
Q

Smooth muscle is…

A

Non-striated muscle which is controlled involuntarily by the autonomic nervous system

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5
Q

Cell surface membrane of muscle cell

A

Sarcolemma

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6
Q

T-tubules are…

A

Invaginations of the sarcolemma which conduct charge when a cell is depolarised

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7
Q

Sarcoplasmic reticulums are…

A

Specialised endoplasmic reticulums which contain large storages of calcium ions

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8
Q

Hierarchy of muscle organisation

A

Muscle fibres -> fascicles -> muscle

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9
Q

Muscle fibres are surrounded by

A

Endomysium

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10
Q

Muscle Fascicles are surrounded by

A

Perimysium

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11
Q

Muscles are surrounded by

A

Epimysium

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12
Q

Functional unit of muscle

A

Sarcomere

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13
Q

Z line

A

Actin filaments are anchored

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14
Q

M line

A

Where myosin filaments are anchored

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15
Q

I band

A

Contains only actin filaments

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16
Q

A band

A

Length of a myosin filament - may contain actin also

17
Q

H zone

18
Q

Thin filament

19
Q

Thick filament

20
Q

Tropomyosin runs along…

A

The actin filament and blocks myosin head binding sites

21
Q

Troponin binds…

A

Tropomyosin to actin

22
Q

Troponin I

A

Binds to the actin filament

23
Q

Troponin T

A

Binds to Tropomyosin

24
Q

Troponin C

A

Binds to calcium ions

25
1st stage of muscular contraction
Depolarisation arrives at neuromuscular junction. Conducted by T tubules - causes massive influx of calcium ions from sarcoplasmic reticulum
26
2nd stage of muscle contraction
Calcium binds to Troponin C - causes Tropomyosin to move away from actin filament myosin head binding sites
27
3rd stage of muscular contraction
Myosin heads bind to actin filaments. Power strokes cause the myosin heads to pivot in a rowing motion. This slides the actin filaments towards the M line
28
4th stage of muscular contraction
ATP binds to myosin heads, causing them to unbind from actin
29
What shortens during muscle contraction?
Distance between Z lines, I band, H zone and length of the sarcomere
30
What stays the same during muscle contraction
A band and length of muscle filament
31
Duchenne muscular dystrophy is when…
Dystrophin not produced - muscle fibres tear on contraction - muscle weakness
32
Sufferers of duchenne muscule dystrophy are usually…
In a wheelchair by age 12