muscles Flashcards

(54 cards)

1
Q

what surrounds muscle fascicles

A

perimysium

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2
Q

what surrounds muscle organs

A

epimysium

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3
Q

what is sacromella

A

membrane of muscle fibre

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4
Q

what is the role of a T- tubule

A

conduct charge to the muscle

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5
Q

what is contained in the muscle sarcoplasm

A

glycosomes and myoglobins

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6
Q

what is stored in sarcoplasmic reticulum

A

calcium ions

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7
Q

what is in the H zone of sarcomere

A

myosin

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8
Q

what is in the I band of sarcomere

A

actin only

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9
Q

what is in the a band of sarcomere

A

actin and myosin

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10
Q

in the first stage of cross bridge cycling describe the action of calcium ions

A

binds to troponin, causing tropomyosin to move , exposing actin binding sites

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11
Q

what causes a power stroke

A

myosin head rotates releasing ADP and phosphate

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12
Q

what molecule is responsible for detaching the myosin head from actin in cross bridge cycling

A

ATP

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13
Q

how does calcium ions get recycled into the sacroplasmic reticulum in excitation contraction coupling

A

ATP driven pumps

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14
Q

how does muscle stimulation end

A

acetylcholinase breaks down acetylcholine in receptor site on muscle neurone

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15
Q

creatine phosphate is an energy source for what type of muscle contraction

A

fast twitch

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16
Q

what is the name of the process that uses oxygen to make ATP in aerobic respiration

A

oxidative phosphorylation

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17
Q

what is the name of the process that uses glucose to make ATP in aerobic respiration

A

glycolysis

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18
Q

what is the other name for type I muscle fibres

A

slow oxidative

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19
Q

what is the other name for type IIa muscle fibres

A

fast oxidative

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20
Q

what is the other name for type IIb muscle fibres

A

fast glycolytic

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21
Q

what muscle fibres use oxidative phosphorylation as ATP source

A

Type I/ slow oxidative and Type II / fast oxidative

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22
Q

glycolysis what muscle fibres use oxidative phosphorylation as ATP source

A

Type IIb/ fast glycolytic

23
Q

what is the origin of muscle

A

site of muscle attachment to stationary bone

24
Q

what is the insertion of muscle

A

site of muscle attachment to moving bone

25
what is agonist muscle
muscle that contracts
26
what is antagonist muscle
muscle that relaxes
27
what is the synergist muscle
muscle that assist the agonist
28
what is the fixator muscle
muscle that provides stabilisation at origin
29
what is in the middle of a first class lever
fulcrum
30
what is in the middle of a second class lever
load
31
what is in the middle of a third class lever
effort
32
what is muscle hypertrophy
muscles are large in proportion to body fat
33
what causes muscle hypertrophy (2)
hormones and genetics
34
what is disuse atrophy
inactivity causing muscle wasting
35
what causes disuse atrophy (2)
paralysis bedrest
36
what is sarcopenia
loss of muscle mass due to ageing
37
what causes sarcopenia (4)
hormones reduced nervous stimulation disuse poor diet
38
what is muscle spasm
involuntary contraction that lasts a short time
39
what causes muscle spasm
nerve malfunction
40
what is muscle cramp
long involuntary contraction
41
what causes muscle cramp
sustained exertion
42
what is muscle strain
muscle overstretched or torn
43
what causes muscle sprain
ligament tear
44
what is affected in the autoimmune disease myasthenia graves
Ach receptors at NMJ
45
what is myopathy
disease that attacks muscle fibres causing weakness and paralysis
46
what is another name for Duchenne's
Beckers dystrophy
47
what is duchennes
degenerative disease causing weakness and wasting of muscle (X-chromosome linked)
48
that is the action of botulism
inhibits acetylcholine release at NMJ
49
what are symptoms of botulism
paralysis dry mouth loss of sweat
50
what are complications of botulism
respiratory or heart failure
51
what happens at NMJ if you have organophosphate poisoning
acetylcholinase is inhibited, no stop in nervous stimulation
52
who is organophosphate poisoning common in (2)
farmers cholingeric syndrome
53
what do you take for organophosphate poisoning
atropine
54
what are symptoms of organophosphate poisoning
SLUDGE salivation lamination urination diarrhoea GI stress emesis