Muscles Flashcards

1
Q

What attaches skeletal muscles to the bone

A

Tendons

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2
Q

What do ligaments attach

A

Bone to bone

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3
Q

Why can bones act as levers

A

They are rigid

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4
Q

What are antagonistic pairs

A

Muscles that work together to move a bone
Agonist = contracts
Antagonist = relax

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5
Q

What are muscles made of

A

Muscle fibres

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6
Q

What is the cell membrane of muscle fibres called

A

Sarcolemma

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7
Q

What is the cytoplasm of muscle fibres called

A

Sarcoplasm

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8
Q

What are the folds in the sarcolemma called

A

Transvers (T) tubules

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9
Q

What is the function of the t tubules

A

Spread electrical impulses throughout sarcoplasm to reach all parts of the muscle fibre

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10
Q

What is the function of the sarcoplasm in reticulum

A

Stores and releases Ça ions

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11
Q

What is an adaption of muscle fibres

A

Lots of mitochondria for ATP

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12
Q

What does multinucleate mean

A

Lots of nuclei

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13
Q

What is the name of the thick myofilament

A

Myosin

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14
Q

What is the name of the thin myofilament

A

Actin

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15
Q

What is the dark band on a myofibril

A

Myosin and actin

A band

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16
Q

What is the light band on a myofibril

A

Actin only

I band

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17
Q

What is at the end of each sarcomere

A

Z line

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18
Q

What is the middle of a sarcomere

A

M line

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19
Q

What area only contains myosin

A

H zone

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20
Q

Explain the sliding filament theory

A

Myosin and actin filaments slide over each other making the sarcomere contract. Not contracting themselves.
The simultaneous contraction of lots of sarcomeres mean the muscle fibres contact

21
Q

What happens to the individual sarcomeres as the muscle fibres contacts

A

A band stays the same length
I band shorter
H zone shorter
Sarcomere overall gets shorter

22
Q

What is the structure of myosin

A

Has a globular head that’s hinged to move
It has 1 binding site for actin
And 1 binding site for ATP

23
Q

What is the structure of actin

A

Has a binding site to myosin = actin myosin binding site

24
Q

What the status of the actin myosin binding site at rest

A

It’s blocked by tropomypsin

25
Why does the actin myosin binding site being blocked mean the myofilaments can’t slide
The myosin heads can’t bind to the actin myosin binding site
26
Explain how muscle contract
1. Ap from motor neurone stimulates muscle cells 2. Sarcolemma depolarised 3. Depolarisation spreads by t tubules to sarcoplasmic reticulum 4. Ça released into sarcoplasm by sarcoplasmic reticulum 5. Ça binds to protein attached to tropomyosin 6. Protein changes shape. 7. Tropomyosin pulled out of actin myosin binding site on actin 8. Binding site is exposed 9. Myosin head binds to actin forming an actin myosin cross bridge 10. Ça activate ATP hydrolase = breaks down ATP 11. Energy from ATP used to bend myosin head 12. Pulling actin 13. Energy from ATP breaks actin myosin cross bridge 14. Myosin head reattaches to another binding site further along actin filament 15. Sarcomere shortens
27
What happens to the muscle when it stops being stimulated
Ça ions leave binding site Move back into sarcoplasm Reticulum by at Tropomyosin moves back to block actin myosin binding sites Actin filaments slide back to the relaxed positions Sarcomere lengthens
28
How would u tell from the sarcomere it is not contracted
No actin myosin cross bridges
29
How is atp generated by aerobic respiration
Oxidative phosphorylation in mitochondria
30
Where does oxidative phosphorylation happen
Mitochondria
31
When is aerobic respiration a good atp source
Long duration | Low intensity
32
How is atp made during anaerobic respiration
Glycolysis makes pyruvate | Pyruvate -> lactate (by lactate fermentation)
33
Why can anaerobic respiration only be used in short periods
Lactate builds causing muscle fatigue
34
How is atp made by the atp-phosphocreatine system
Phosphorylate ADP by adding a pi group from PCr (créatine)
35
Where is PCr stored
Inside cells
36
How fast does the ATP-PCr system make atp
Very quickly
37
What type of excercise is the PCr-AtP system used for
Short duration | High intensity
38
Is atp-pcr system anaerobic or aerobic
Anaerobic
39
Is the atp-pcr system lactic or alactic
Alactic
40
What is créatine broken down into
Creatinine
41
Where is créatine broken down
Kidney
42
Who might have high creatinine levels
People who exercise a lot People with high muscle mass People with kidney damage
43
When are slow twitch muscle fibres used
Used for posture Used in endurance Long duration
44
What type of respiration do slow twitch muscle fibres use
Aerobic
45
What type of respiration do fast twitch muscle fibres use
Anaerobic
46
What are 2 specialisation of slow twitch muscle fibres
Lots of mitochondria = supply muscles with energy from atp | Lots of blood vessels = supply muscles with oxygen
47
When are fast twitch muscle fibres used
Fast movements Short duration High intensity
48
Why are slow twitch fibres red
Have lots of myoglobin (stores oxygen)
49
Why are fast twitch white
Don’t have much myoglobin | Don’t store much oxygen