Musculoskeletal System Flashcards

(42 cards)

1
Q

What are bursae?

A

Fluid-filled sacs - reduce friction.

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2
Q

What is a ligament?

A

Fibrous connective tissue - joins bones/cartilage.

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3
Q

What is a tendon?

A

Fibrous connective tissue - joins muscle to one.

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4
Q

What are the 3 types of joints?

A

Fibrous, cartilaginous, synovial.

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5
Q

Connective tissue: fat (function) and fibrous (state the 2 types)

A

Fat: insulation & shock absorption.
Fibrous: (A) White fibrous (dense tissue composed of collagen bundles) - forms ligaments, tendons & protective membranes around muscle (B) Yellow (elastic).

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6
Q

State the 3 types of cartilage & where they are located.

A

Hyaline (articular cartilage in joints & respiratory system - trachea), fibrocartilage (articular discs in joints, intervertebral discs & around edge of ball & socket), & elastic (external ear, auditory tube, epiglottis & larynx).

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7
Q

State the 3 regions of long bone:

A

Epiphysis, diaphysis, metaphysis.

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8
Q

What & where is the epiphyseal plate? State its function.

A

The growth plate in the metaphysis of long bone.

Site of bone growth & ossification in children.

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9
Q

Describe Ruffini corpuscles & Paciniform endings.

A

Mechanoreceptors which detect stretch & pressure.

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10
Q

Describe the structure of a synovial joint.

A

2 bones covered by articular cartilage - joint cavity contains synovial fluid, covered by a synovial membrane and articular capsule.

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11
Q

Function of hinge joints.

A

Flexion & extension.

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12
Q

Function of pivot joints

A

Rotation around one axis.

E.g. elbow

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13
Q

Function of Bicondylar joints

A

movement in one axis & limited rotation around another axis.

E.g. Knee

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14
Q

Function of Condylar joints

A

Movement in 2 planes (biaxial) - flexion, extension, abduction, adduction.
E.g. wrist.

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15
Q

Function of Ball and socket joints

A

Movement in 3 planes (multi-axial).

E.g. hip & shoulder

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16
Q

Function of Saddle joints.

A

Biaxial.
Permit flexion, extension, abduction, adduction, circumduction.
E.g. carpometacarpal joint of thumb.

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17
Q

Function of synovial fluid.

A

Lubricates joint - reduces friction between articular surfaces.

18
Q

Compare abduction & adduction.

A

Abduction: moving away from centre of body.
Adduction: moving toward centre of body.

19
Q

State the spinal regions & no. of vertebrae in each.

A

Cervical (C1-7)
Thoracic (T1-12)
Lumbar (L1-5)
Below: sacrum & coccyx.

20
Q

State & point to the major muscles of the body (anterior).

A
frontalis.
zygomaticus
sternocleidomastoid
trapezius
deltoid
pectoralis major
biceps brachii
rectus abdomina
external oblique
sartorius
gracilis
abbudctor longus
rectus femoralis
vastus laterals
21
Q

State & point to major muscles of body (posterior)

A
trapezius
infraspinatus
teres minor
deltoid
teres major
triceps brachii
latissimus dorsi
external oblique
gluteus maximus
biceps femoris
semitendinosus
gastrocnemius 
calcaneal tendon
22
Q

Name the 7 main Tarsal bones

Tiger Cubs Need MILC

A

Talus, Calcaneus, Navicular, Medical cuneiform, Intermediate cuneiform, Lateral cuneiform, Cuboid.

23
Q

Define Synctium.

A

a multinucleated cell.

Often cells interconnected by specialized membrane with gap junctions.

24
Q

Describe smooth muscle.

A

Involuntary, non-striated muscle.
Forms walls of blood vessels & hollow organs (stomach).
Contracts less powerfully than skeletal, but maintains for longer.

25
Describe skeletal muscle.
Voluntary, striated, MULTINUCLEATE. Most attached to bones by tendons. Develop great force, tire quickly. Bodily movement & reaction to external stimuli.
26
Describe cardiac muscle.
Involuntary, striated, mononucleate, many mitochondria. Abundant myoglobin reserve (O2 storage) Intercalated discs.
27
Describe an intercalated disc.
Intercellular attachment of cardiomyocytes - gap junctions.
28
What is a sarcomere?
A single contractile unit: contains actin & myosin filaments.
29
Sarcomere: A band
Thick (myosin) filament
30
Sarcomere: I band
Thin (actin) filaments.
31
Sarcomere: M line
centre of sarcomere: thick filaments attach
32
Sarcomere: H zone
Thick filaments only
33
Sarcomere: Z disc
filamentous protein network: attaches actin myofilaments.
34
Sarcomere: titin filaments
elastic chains of polypeptides - align thick & thin filaments
35
State the resting length of a sarcomer
2-2.2ym
36
Mechanism of contraction (skeletal & cardiomyocytes).
Contraction: DEPOLARISATION - 1. Excitation -> Na+ channels 2. L-type Ca2+ channels 3. Ca2+ induced Ca2+ release from RyR (ryanodine receptors) - sarcoplasmic reticulum. 4. Ca2+ stimulates contraction.
37
Mechanism of Relaxation (skeletal & cardiomyocytes)
REPOLARISATION: 1. Ca2+ reuptake into SR 2. Ca2+ withdrawal to ECF 3. Ca2+ exchanged for 3Na+ via Na+/Ca2+ exchanger (NCX) , then 3Na+ for 2K+ via Na+/K+ -ATPase. 4. K+ channel activation.
38
Describe the mechanism for smooth muscle contraction.
1. Excitation-depolarisation due to voltage-gated L-type Ca2+ channel opening. 2. Ca2+ -induced Ca2+ release from ER/SR via RyR -> increased [Ca2+] 3. Ca2+ binds calmodulin (CaM) 4. Ca2+ -CaM complex activates Myosin light chain complex (MLCK) 5. MLCK phosphorylates myosin head & stimulates contraction.
39
What is the importance of Ca2+?
- DEPOLARISATION & propagation of excitation - Activates muscle contraction - SIGNAL MOLECULE & SECOND MESSENGER
40
What are the 4 stages of muscle excitation
Twitch, wave summation, incomplete tetanus & complete tetanus.
41
What is a fascicle?
Bundle of parallel fibres bound by dense connective tissue. | Bound together form muscles.
42
Describe the phases of contraction
1. REST: ATP is hydrolysed. 2. ACTION POTENTIAL: Ca2+ binds to troponin -> conformational change -> MYOSIN BINDS ACTIN. 3. Powerstroke occurs: sarcomere contracts; ADP & P dissociate from myosin. 4. New ATP binds myosin -> detaches from actin. ATP -> ADP + P causes reckocking of myosin head.