Mutations During Meiosis Flashcards

(7 cards)

1
Q

How does a gene mutation occur

A

A change in the base sequence of chromosomes

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2
Q

What happens in a genetic mutation

A
  • mutation changed amino acid coded for
  • changed primary structure which is the sequence of amino acids
  • this changes the tertiary structure
  • as the h, ionic and disqualified bridges form in different places
  • changes 3d shape and 3 function
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3
Q

Why do not all base substitutions cause a change in the sequence of amino acids

A

Due to the degenerate nature of the genetic code

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4
Q

What are the 3 mutations

A

Substitution mutation
Frame shift mutation
Non disjunction mutation

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5
Q

What is a substitution mutation

A

One base is swapped for another
Often doesn’t have an affect due to degenerate
Only affects 1 amino acid coded

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6
Q

What is a frame shift mutation

A

Insertion or deletion of a base occurs
All following codons are affected
Large effect -> prim stcrure-> tertiary-> diff 3d

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7
Q

What is a non disjunction mutation

A

Sister chromatids don’t separated in meiosis 2 leading to extra chromosomes

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