Mycoplasma Genitalium

Question 1

What causes non-gonoccoal urethritis?

Answer 1

• Chlamydia trachomatis (most common)
• Mycoplasma genitalium (more symptoms)

Question 2

What can a mycoplasma genitalium infection cause?

Answer 2

• urethritis
• epididymitis
• cervicitis
• endometritis
• PID
• reactive arthritis
• preterm delivery
• tubal infertility

Question 3

Presentation of non-gonococcal urethritis

Answer 3

• urtheritis
• urethral discharge

Question 4

Investigations of mycoplasma genitalium

Answer 4

• NAAT
• women: vaginal swabs
• men: first urine sample in morning
• check every positive test for macrolide resistance
• test of cure after treatment

Question 5

Management of mycoplasma genitalium

Answer 5

• first line: doxycycline 7 days followed by azithromycin for 2 days
• second line: moxifloxacin
• pregnancy/breastfeeding: azithromycin alone
• refer to GUM