Myelin Basic Protein IN CSF

Question 1

What does the presence of Myelin Basic Protein in CSF indicate?

Answer 1

• Indicates recent destruction of the myelin sheath
• That protects the axon of neurons, a condition known as demyelination.

Question 2

What can the measurement of Myelin Basic Protein in CSF be used for?

Answer 2

• It can be used to monitor the course of Multiple Sclerosis.

Question 3

What is theorized to trigger the inflammatory response in Multiple Sclerosis (MS)?

Answer 3

• Molecular Mimicry is theorized to trigger the inflammatory response in MS.

Question 4

Name some viruses associated with Molecular Mimicry in MS.

Answer 4

• EBV, Measles, HSV, VZV, Rubella, Influenza C, and HHV-6 are associated with Molecular Mimicry in MS.

Question 5

Besides monitoring MS, what other potential benefit does the measurement of Myelin Basic Protein in CSF offer?

Answer 5

• It may also provide a valuable measure of the effectiveness of current and future treatments for MS.

Question 6

What is the primary cell responsible for producing the myelin sheath in the nervous system?

Answer 6

• Schwann cells produce the myelin sheath.

Question 7

What happens when an axon becomes exposed due to demyelination?

Answer 7

• Demyelination results in the axon becoming exposed.