Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Y2 Haematology > Myelodysplastic disorders** > Flashcards

Myelodysplastic disorders** Flashcards

1
Q

What is myelodysplasia?

A

abnormal maturation and proliferation of haematopoietic stem cells in bon marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pathophys of myelodysplasia?

A

deformed cells cannot get into blood stream

often affects red cells, granulocytes, platelets (pancytopenia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Presentation of myelodysplasia?

A

often in elderly
isolated anaemia
general - fatigue/ SOB/ pallor/ petechiae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Symptoms of myelodysplasia?

A

depends on affected cell line:

neutropenia - recurrent infections
thrombocytopenia - easy bruising/ bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lab findings/ investigation of myelodysplasia?

A

cytopenias in FBC
blood film = morphological disorder of cell line
red cell macrocytosis
bone marrow exam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

WHO classification of myelodysplasia?

A

6 subtypes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What condition can myelodysplasia develop into and why?

A

AML - build of of blasts in bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Treatment of Myelodysplasia?

A

Blood and platelet transfusions
thalidomide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Y2 Haematology (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions