N235 Flashcards
(149 cards)
Thalamus and hypothalamus are part of what system
Limbic system
What does the forebrain consist of
Cerebellum and diencephalon (connects cerebellum to limbic)
A few major neurotransmitter categories
Chollinergics
Monoamines
Amino acids
Neuropeptides
Chollinergics
Acetylcholine
Primary in junctions of nerves and muscles
Plays a role in most all functions
Could play a role in Parkinson’s and Alzheimer’s
Monoamines
Norepinephrine
Dopamine
Serotonin
Histamine
Monoamine
Norepinephrine
Creates activity in the post synaptic terminal of nerves in ANS
Used for fight or flight
Regulates mood, cardiovascular system, sleep.
What mood disorders can be implicated from norepinephrine
Depression
Mania
Anxiety
Schizophrenia
Monoamine
Dopamine
Functions to regulate mood
Movement/ coordination
Increased dopamine levels are seen in what mood disorders
Mania
Schizophrenia
Monoamine
Serotonin
Play a role in sleep arousal, libido, mood, agitation.
Seen in schizophrenic disorders as well as anxiety states
Monoamine
Histamine
Functions as allergic and inflammatory reactions.
Sustaining wakefulness
Shown to be associated to some depressive illness
Amino acids types
Inhibitory and excitatory amino acids
Two of the biggest inhibitory amino acids
Gamma aminobutyic acid (GABA)
Glycine
How does GABA and glycine work
They prevent excitation of postsynaptic terminal impeding the impulse of electrical current. (Stops/slows down the message signal)
What disorder has GABA been implicated to
Anxiety disorders
Movement disorders
Some forms of epilepsy
What disorders has glycine been implicated with
Spastic disorders
What are the two common excitatory amino acids
Glutamate
Aspartate
Excitatory amino acids role
Relay sensory information
Regulate motor and spinal reflexes
Excitatory amino acids are implicated in
Neurodegenerative disorders
Huntingtons disease
Temporal epilepsy
The longer you are awake for what happens to your inhibitory amino acid numbers
They increase
Three main neuropeptides
Opioid peptides
Substance P
Somatostatin
Circadian rhythm
24 hour sleep wake cycle
Abnormal circadian rhythm correlated to
Depression
Bipolar disorder
Seasonal affective disorder
Neurochemicals that effect sleep
Serotonin
Norepinephrine
Acetylcholine
Melatonin