Narcolepsy Flashcards
1
Q
Seigal
A
Cells in dogs during sleep were activated in narcoleptic dogs when awake
2
Q
Honda
A
Increase in HLA in neuroleptic patients
3
Q
Mignot (critique)
A
Not all people with the HLA variant had narcolepsy
4
Q
Thannickal
A
Lack of hypocretin producing cells in hypothalamus caused narcolepsy.
5
Q
Gordon et al
A
Injected antibodies of narcoleptic a into 9 rats and found they developed narcolepsy.
6
Q
Dement
A
Mice that lack hypocretin in their brain had symptoms of narcolepsy
7
Q
Mignot… Again
A
Narcolepsy is not due to inherited factors as there is no familial link. But, an auto immune attack could have caused reduction in hypocretin.
8
Q
Vogel
A
REM sleep first occurs in the onset of narcolepsy
