nausea + vomiting

Question 1

name examples of anti-emetics that have an increased risk of extrapyramidal side effects

Answer 1

Haloperidol, metoclopramide, perphenazine, prochlorperazine have a risk of extra-pyramidal side-effects

extra-pyramidal effects: Parkinsonian symptoms, dystonia = abnormal face/body movements, akathisia = restlessness, tardive dyskinesia = rhythmic, involuntary tongue, face and jaw movements

Question 2

which antiemetic has no risk of extrapyramidal side effects

Answer 2

cyclizine

note: extra-pyramidal effects: Parkinsonian symptoms, dystonia = abnormal face/body movements, akathisia = restlessness, tardive dyskinesia = rhythmic, involuntary tongue, face and jaw movements

Question 3

which antiemetic is for moderate- severe nausea induced by chemotherapy

Answer 3

Ondansetron

Question 4

which antiemetic is used for for nausea and vomiting in palliative care

Answer 4

Metoclopramide

Question 5

what is the interaction between Domperidone + Methadone

Answer 5

Domperidone increases the risk of QT-prolongation when given with methadone. Manufacturer advises avoid

note: domperidone is used to treat nausea + vomiting

Question 6

which antiemetics should not be used in patients with parkinsons disease

Answer 6

Haloperidol, metoclopramide, perphenazine, prochlorperazine

because they have a risk of extra-pyramidal side-effects

extra-pyramidal effects: Parkinsonian symptoms, dystonia = abnormal face/body movements, akathisia = restlessness, tardive dyskinesia = rhythmic, involuntary tongue, face and jaw movements