Neoplasia

Question 1

Dx agente citotoxico alquilante

Answer 1

Mecloretamina
Ciclofosfomida
Isofosfomida
Melfan
Clorambucilo

Question 2

Fx se uso 1ra guerra mundial

Answer 2

Mecloretamida

Question 3

Semivida mecloretamida

Answer 3

Corta

Question 4

Uso mecloretamida

Answer 4

Linfoma hodking

Question 5

Adm mecloretamida

Answer 5

Iv

Question 6

Toxicidad mecloretamida

Answer 6

Hematog

Question 7

Fx más usado alquilante

Answer 7

Ciflofosfomida
Clorambucilo

Question 8

Adm alquilante iv y vo

Answer 8

Ciclofosfomida
Clorambucilo

Question 9

Adm solo vo de alquilante

Answer 9

Isofosdomida
lomustina

Question 10

Adm solo iv alquilante

Answer 10

Mecloretamina

Question 11

Ciclofosfomida
Adm
E
Dist

Answer 11

V.o iv
Orina
Amplia

Question 12

Clicofosfomida toxic

Answer 12

Alopecia mielosupresiok emesis

Question 13

Ciclofosfomida uso

Answer 13

Mamá
Ovario
Leucemia
Linfomas ambos

Question 14

Isofosfomida uso

Answer 14

Sarcoma
vejiga
pulmonar
cuello uterino

Question 15

Interfiere síntesis adn alquilante

Answer 15

Melfan

Question 16

Toxic porque actúa en cell sanas alquilante
Que cell?
Que fx

Answer 16

Melfan
Sangre y digestivo

Question 17

Uso melfan

Answer 17

Melanoma, hueso, tejido blando y ovario

Question 18

Toxic
Clorabucilo

Answer 18

Mielosuprwcion alopecia y emesis

Question 19

Diferencia uso de ciclofosfomida y Clorambucilo

Answer 19

Ciclofosfomida ambos linfomas
Clorambucilo solo no Hodking

Question 20

Alquilante nitrosourea

Answer 20

Lambustina

Question 21

Alquilante inestable en solución acuosa

Answer 21

Mecloretamina

Question 22

Solubilidad lomustina

Answer 22

Alta

Question 23

Alquilante con el nivel plasmatico más bajo y cuanto es

Answer 23

30%
Lombustina

Question 24

Uso lomustina

Answer 24

Cancer cerebral y ambos linfomas

Question 25

Inhibidor topoisomerasa

Answer 25

Irinotecan

Question 26

Abs irinotecan

Answer 26

IV

Question 27

Mec accion irinotecan

Answer 27

Interfiere accion enzima topoisomerasas

Question 28

Único met hepat hidrolisis Que fx

Answer 28

Irinotecan

Question 29

Toxic Hemato y digestivo

Answer 29

Melfan Irinotecan

Question 30

Toxic irinotecan

Answer 30

Gasto y hemato

Question 31

Usi irinotecan

Answer 31

Carcinoma metástasis Cancer esófago Páncreas Cuello uterino

Question 32

Fx antimetabolitos

Answer 32

Metrotrexato Aziatropina Mercaptopurina Fluorouracilo Fludarabina

Question 33

Antimetanolito Fx antifolato

Answer 33

Metotrexato

Question 34

Mec accion metotrexato

Answer 34

Inhibe enzima dihidrofolato No se forma purina ni pirimidina

Question 35

Toxic metrotrexato

Answer 35

Medular Gástrico Renal Pulmonar Hepat Cutáneo Snc

Question 36

Adm vo iv im

Answer 36

Meteotrexato

Question 37

Análogo purina

Answer 37

Aziatropina Mercaptopurina

Question 38

Mec acc análogo purina

Answer 38

Antagonista met purina inhibe adn Arn

Question 39

Análogo purina no inhibe mucho arn

Answer 39

Mercaptopurina

Question 40

Análogo purina se usa pra profilaxis transplante

Answer 40

Aziatropurina

Question 41

Unión prot 20% Baja Fx

Answer 41

Mercaptopurina

Question 42

Adv de análogos purinas

Answer 42

Fiebre Hematologico Hematoma Hemorragia Escalofríos Dolor garganta

Question 43

Mercaptopurina + alopurinol

Answer 43

aumenta toxic mercaptopurina

Question 44

analogo pirimidas

Answer 44

5- flurouracilo

Question 45

5- flurouracilo analogo pirimidas mec acc

Answer 45

inhibe sintesis base timidina

Question 46

5- flurouracilo uso

Answer 46

colon mama digest recto

Question 47

analogo adenosina

Answer 47

fludarabina

Question 48

analogo adenosina fludarabina

Answer 48

inhibe sint adn impide proliferacion cell

Question 49

analogo adenosina fludarabina uso

Answer 49

neoplasia linfoma y leucemia

Question 50

analogo adenosina fludarabina adv

Answer 50

anemia trombocitopenia neutropenia

Question 51

derivado palatino

Answer 51

cispalatino

Question 52

cispalatino mec

Answer 52

afecta adn polimerasa

Question 53

adm fludarabina

Answer 53

iv vo

Question 54

cispalatino adm

Answer 54

iv

Question 55

cispalatino toxic

Answer 55

renal y neuropatia

Question 56

antitumural antibiot

Answer 56

bleomicina actinomicina d

Question 57

bleomicina mec accion

Answer 57

rompe cadena simple o doble

Question 58

antitumural antibiot soluble en agua diodisp

Answer 58

bleomicina baja

Question 59

bleomicina uso

Answer 59

carcinoma epidermis tumor germinal linfomas

Question 60

bleomicina toxic

Answer 60

tos no productvia

Question 61

actinomicina d

Question 62

actinomicina d toxic

Answer 62

gastro mielosupresion dermica

Question 63

actinomicina d uso

Answer 63

wilms y niños

Question 64

alcaloides de vinca deriva de

Answer 64

catharanthus roseus

Question 65

alcaloides de vinca fx

Answer 65

vincristina vinblastina vinorelbina

Question 66

alcaloides de vinca mec acc

Answer 66

inhibe div cell cancerosa actua en tobulina, no se forma huso mitotico

Question 67

alcaloides de vinca uso

Answer 67

cancer inmunosupresor

Question 68

vincristina toxic

Answer 68

alopecia

Question 69

vinblastina toxci

Answer 69

neutropenia

Question 70

vinorelbina toxic

Answer 70

mucosistis