Nephritic Syndromes

Question 1

Renal Pathology:
Light Microscopy:

Diffuse proliferation

Answer 1

PSGN

Inc ASO
Positive streptozyme
low c3-c9, normal C1 C4

Question 2

Renal Pathology:
Light Microscopy:

Focal Proliferation

Answer 2

IgA Nephropathy

Positive IgA
IgA in dermal Capillaries

Question 3

Renal Pathology:
Light Microscopy:

Focal to diffuse proliferation with CRESCENTS

Answer 3

Goodpasture Syndrome

Pulmonary hemorrhage; IDA
Positive anti-GBM antibodies

Question 4

Renal Pathology:
Light Microscopy:

Crescentic GN

Answer 4

Idiiopathic Rapidly Progressing GN

Positive ANCA to some

Question 5

Renal Pathology:
IF: Granular IgG, C3
EM: Subepithelial Humps

Answer 5

PSGn

Question 6

Renal Pathology:
IF: Diffuse Mesangial IgA
EM: Mesangial deposits

Answer 6

IgA Nephropathy

Follows viral syndrome ( URTI/ GI)

Question 7

Renal Pathology:
IF: Linear IgG, C3
EM: No deposits

Answer 7

Goodpasture Syndrome

Question 8

Renal Pathology:
IF: no immune deposits
EM: No deposits

Answer 8

Idiopathic Rapidly Progressing GN