Nervous Coordinatiom Flashcards
(10 cards)
Structure of a myelinated motor neurone
Axon terminal
Axon:
-contains myelin sheaths made out of Schwann cells
-node of ranvier between the sheaths
Cell body
Dendrite
What is resting potential
Axon has a negative charge relative to the outside
How can resting potential be established
Na+/K+ pump - active transport:
-3na+ out and 2K* into acon
Creates an electrochemical gradient
-higher K conc inside and higher Na conc outside
Differential membrane permeability:
More permanent to K (moves out via facilitated diffusion)
Less permeable to Na as channels are closed
What are the 5 steps to a action potential
Stimulus
Depolarisation
Repolarisation
Hyperpolarsation
Resting potential
Describe how an action potential is generated
Stimulus:
-Na+ channels open
-Na+ diffuse into axon down electrochemical gradient(causing depolarisation)
Depolarisation:
-is threshold potential is reached, action potential is generated
-more voltage Na gates open
-Na diffuses in more rapidly
Re-polarisation:
-voltage Na gates close
-voltage K gates open
- K diffuses out of axon
Hyperpolarsiation:
-K channels are slow to close so they slightly release to many K
Resting potential:
-restored via a Na/K pump
Non-myelinated vs myelinated in generating nerve impulse
Non:
-action potential passes as a wave of depolarisation
-lost of Na in a region increases permeability by causing voltage gates Na channels open, adjoining regions also depolarise
My:
-myelination proved electrical insulation
-depolarisation of axon at nodes of ranvier
-resulting in salatory conduction
-no depolarisation along the whole length of axon
What would damage to the myelin sheath do
Less saltatory conduction so depolarisation occurs for the length of the whole of the axon
-nerve impulse takes longer
Ions/depolarisation may leak to other neurones
-causing wrong muscle contraction
What is the refractory period
Time taken to restore axon to resting potential when no further action potential can be generated
As na channels are closed
Importance of refractory period
Ensure that action potentials don’t overlap
-limits freq of impulse transmission do there isn’t over reaction to a stimulus
Ensure that action potentials travel in 1 direction (can’t be propagated in a refractory period)
Factors that affect speed of conduction
Myelination:
-depolarisation at nodes of ranvier only, saltatory conduction, dosent have to travel the whole length of axon
Axon diameter:
-bigger diameter means less resistance to flow of ions
Temp:
-increases rate of diffusion
-but proteins/enzymes could denature at a point