Nervous System Flashcards
(22 cards)
Specialized cells capable of transmitting electrical impulses & then translating them into chemical signals are known as ?
Neurons
The nucleus, ER, & ribosomes are located in which structure ?
Cell body (soma)
Appendages that receive incoming signals from other cells are known as ?
Dendrites
*messages integrated in axon hillock
Mammalian nerve fibers are coated in which signal loss prevention structure ?
Myelin
* produced by oligodendrocytes (CNS) & schwann cells (PNS)
Chemicals that transmit info between neurons are known as ?
Neurotransmitters
The space between 2 neurons where neurotransmitters are secreted is known as the what ?
Synaptic cleft
Cells that support and myelinate neurons are known as ?
Neuroglia (glial cells)
The net electrical potential difference that exists across the cell membrane due to movement of charged particles is known as ?
Resting potential
*-70 mV for neurons
What does the cell membrane have to facilitate the movement of K+ out of the cell ?
K+ leak channels
The potential difference that represent the K+ equilibrium is known as ?
Equilibrium potential of K+
*-90 mV
The movement of Na+ into the cell is facilitated by which channels?
Na+ leak channels
-equilibrium potential of Na+ is +60 mV
A form of active transport that moves Na+ & K+ against their conc. gradients is known as ?
Na/K ATPase
-3 Na+ out, 2 K+ in
Excitatory input causes what type of rxn to the neuron ?
Depolarization (raise membrane potential)
*If high enough to reach threshold (-55 to -40 mV), then action potential will be triggered
Inhibitory input leads to what type of rxn in a neuron ?
Hyperpolarization (lowers membrane potential)
What does the electrochemical gradient promote in a cell?
Migration of Na+ into the cell
What happens to Na+ channels when Vm approaches +35 mV ?
Channels inactivated
What are the 3 different states that the Na+ channel can exist in ?
- Closed: before cell reaches threshold but after inactivation has been reversed
- Open: from threshold to approx +35 mV
- Inactive: approx +35 mV to resting potential
The efflux of K+ & the restoration of the negative membrane is known as ?
Repolarization
*Makes the neuron refractory to further action potentials
What period constitutes that no amount of stimulation can cause another action potential to occur ?
Absolute refractory period
The period in which there must be a greater than normal stimulation to cause an action potential due to the membrane starting from a potential lower than the resting potential is known as ?
Relative refractory period
If a neuron signals to a gland or muscle instead of another neuron, then the postsynaptic cells is termed what ?
Effector
How are neurotransmitters regulated ?
- Enzymes
- Reuptake carriers
- Diffusion