Nervous system D/o-PPt -Josh Flashcards Preview

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Flashcards in Nervous system D/o-PPt -Josh Deck (46):
1

Parkinson's Disease:

PD is known as a neuro______ diseaae

 

NeuroDEGENERATIVE

 

2

 

Parkinson's Disease:

what is the #1 risk factor?

Increasing Age

3

Parkinson's Disease:

is a deficiency of dopaminergic innervation of the Basal Ganglia, from the _____ ______

Substantia Nigra

4

Parkinson's Disease:

Degeneration of the ___________ pathway leads to depletion of the neurotransmitter dopamine

Nigrastriatal

5

Parkinson's Disease:

S/S

 

  • Skeletal Muscle tremor
  • Rigidity
  • Akinesia
  • Bradykinesia
  • Postural Instability

 

6

Parkinson's Disease:

what are the 2 types of regidity?

  1. Plastic rigidity- constant through ROM; lead pipe PROM
  2. Cogwheel rigidity- breif palpable jerks

7

Parkinson's Disease:

what is Akinesia

  • An absence or lack of control of voluntary muscle groups

8

Parkinson's Disease:

what is bradykinesia

Slowness of voluntary movement

9

Parkinson's Disease: Anesthesia

do these pt's continue Levodopa preop

yepper

10

Parkinson's Disease: Anesthesia

what are 3 pharmacological treatment options

  • Levodopa
  • Synthetic Dopamine Agonist
  • Anticholinergic

11

Parkinson's Disease: Anesthesia

what are 3 drugs to avoid giving to these pt's?

Droperidol

Haloperidol

Alfentanil

12

what is a chronic and progressive autoimmune  d/o involving the demyelination of axons?

MS

13

Multpile Sclerosis:

MS is specific to what part of the nervous system

CNS

14

Multpile Sclerosis:

the irreversible damage is called by what 5 thinks

  • Inflammation
  • Oligodendrocyte injury
  • Demyelination
  • Axonal Degeneration
  • Formation of Plaques

15

Multpile Sclerosis:

Symptoms/ how does it appear for example constant ot remissions

 

  • exacerbations
  • Relapses
  • Remissions
  • eventually Symptoms persist during remissions, leading to severe disability

16

Multpile Sclerosis:

whare does demylination occur (3), and what is the manifestation?

  • Optic Nerve- Visual failure
  • Cerebellum Involvement- Gait disturbances
  • Spinal Cord Lesions- Skeletal muscle weakness/ urinary incontinenc/ Ataxia

17

Multpile Sclerosis: Anesthesia

Surgical stress can exacerbate the symptoms- and a temp change of __C can exacerbate symptoms

1

18

Multpile Sclerosis: Anesthesia

what MR do you want to avoid? why?

DMB (SCh)- d/t hyperkalemia

19

Huntington's Disease:

is a heredity degenerative d/o that is ________ dominant

Autosomal Dominant

20

Huntington's Disease:

effects what 2 parts of the brain?

  • basal Ganglia
  • Cerebral Cortex

21

Huntington's Disease:

it is also know as what name?

Chorea

22

 

Huntington's Disease:

the basal ganglia is depleted of what NT

GABA

23

Huntington's Disease:

S/S

Abnormal movement

Dementia

restlessness

irritabilty

24

Huntington's Disease: Anesthesia

the is an increased sensitivy to which MR ND or Dep?

Both

25

Huntington's Disease: Anesthesia

what 2 meds are great for pre-treatment

  • Droperidol
  • Halperidol

26

What is the functional Abnormality associated w/ at least 1 never root?

  • radiculopathy

27

Radiculopathy:

may be caused by what 3 things?

  1. compression
  2. Inflammation
  3. Acute trauma

28

Huntington's Disease: Anesthesia

Muscles innervated by involved nerve root may display what S/S

  • Atrophy
  • Weakness
  • decreased DTRs
  • sensry alterations

29

what are the 3 types of neuropathies

 

Generalized

focal or multifocal

Generalized symmetric

 

30

what type of Nueropathy affect the cell body of only ONE peripheral nerve?

Generalized

31

Generalized Nueropathy:

what are the 2 types

  1. Motor
  2. Sensory

32

Generalized Nueropathy:

ALS is an example of what type of Generalized Nueropathy:

Motor

33

Generalized Nueropathy:

Leprosy and Industrial poisoning is an example of what type of Generalized Nueropathy:

Sensory

34

What type of Neuropathy affect sensory or motor in one or more nerves?

Focal or Multifocal Neuropathies

35

Focal or Multifocal Neuopathies:

what is an example of this?

Carpal tunnel syndrome

 

36

what type of Neuropathy is SYMMETRIC involement  of sensory, motor, or autonomic fibers?

Generalized Symmetric Polyneuopathies:

37

Generalized Symmetric Polyneuopathies:

what are the 3 types

  1. Distal Axonal Polyneuopathies
  2. Demyelinated Polyneuopathies
  3. Axonal Degeneration

38

Generalized Symmetric Polyneuopathies:

which one of the 3 is the most common?

Distal Axonal Polyneuopathies:

39

Generalized Symmetric Polyneuopathies:

what is an example of Distal Axonal Polyneuopathies:

(hint think distal AKA legs)

DM

ETOH abuse

40

Generalized Symmetric Polyneuopathies:

which one is the least common

Demylinating

41

 

Generalized Symmetric Polyneuopathies:

what is an exaample of the demyelinating

Guillian- barre

42

Generalized Symmetric Polyneuopathies:

how is axonal degeneration done

disatl dgeneration of axon fist followed by degeneration of myelin

43

Myelopathy:

2 types

  1. HIV Myelopathy:
  2. Vascular Myelopathy:

44

Myelopathy:

which one is DIFFUSE degeneration of the spinal cord

HIV Myelopathy:

45

 

Myelopathy:

then I guess... which one is Lateral and posterior spinal colums of the lumbar spinal cord! And progressive spastic paraparesis w/ ataxia

vascular Myelopathy:

46

Thats it

your done