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Histology Term 1 > Nervous Tissue > Flashcards

Nervous Tissue Flashcards

(42 cards)

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1
Q

From where does the PNS and meninges derive from?

A

Neural Crest Cells

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2
Q

How does the CNS differ from the PNS?

A

CNS has:

  • 4 types of glia
  • Blood brain barrier
  • No axonal basal lamina

PNS has:

  • 2 Types of glia
  • Weak BBB
  • Axonal Basal Lamina
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3
Q

How are the CNS and PNS similar?

A
  • Post mitotic neurons

- Invading cells

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4
Q

What are invading cells?

A
  • Blood vessel endothelium

- Immune cells

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5
Q

What is the Nissle Body?

A

-The RER for the neuron

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6
Q

What protein is used for anterograde axonal transport?

A

Kinesin

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7
Q

What protein is used for fast retrograde axonal transport?

A

Dynein

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8
Q

What is contained within the arachnoid layer?

A
  • Blood vessels
  • Trabeculae
  • CSF
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9
Q

What are the three layers of the cerebellar cortex?

A
  • Molecular layer
  • Purkinje Layer
  • Granular layer
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10
Q

What is the intermediate filament of neurons?

A

neurofilament

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11
Q

What kind of intermediate filament will be found in satellite cells?

A

-Vimentin (Arise from neural crest cells)

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12
Q

What levels do the preganglionic sympathetic neurons arise from?

A
  • T 1-12

- L 1-3

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13
Q

What levels do the preganglionic parasympathetic neurons arise from?

A
  • CN III, VII, IX, X

- S 2-4

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14
Q

What is a euchromatic nucleus?

A
  • Light staining areas of nucleas

- Indicate an active cell

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15
Q

Where do glia in the CNS arise from?

A

Neural tube

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16
Q

What is the intermediate filament of glia in the CNS?

A
  • GFAP
  • Gilial Fibrillary Acidic Protein
  • Except Microglia!! (Vimentin)
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17
Q

Where do glia in the PNS arise from?

Study These Flashcards
A

-Neural Crest

18
Q

What is the intermediate filament of glia in the PNS?

19
Q

What are the types of glia in the PNS?

Study These Flashcards
A
  • Schwann Cells

- Satelite cells

20
Q

What cells support neurons in the NS?

Study These Flashcards
A
  • Glia
  • Endothelial cells
  • Immune cells
21
Q

What are the 3 CNS glial cells?

Study These Flashcards
A
  • Oligodendrocytes
  • Astrocytes
  • Ependymal cells
  • Microglia (Non GFAP)
22
Q

What do oligodendrocytes do?

Study These Flashcards
A
  • Mylenation
  • One oligo insulates many neurons
  • NO basal lamina
23
Q

What do astrocytes do?

Study These Flashcards
A
  • Structural component of brain
  • Forms part of blood brain barrier
  • Repair (Scars)
  • NT Pickup
  • Most common tumor source
24
Q

What do ependymal cells do?

Study These Flashcards
A
  • Circulates CSF

- No Basal Lamina

25
What is the most common tumor source in the CNS?
-Astrocytes
26
How do astrocytes act as the blood brain barrier?
-Feet on the capillary and feet on the neuron
27
What do microglia do?
-immune function
28
What intermediate filament is found in microglia?
-Vimentin
29
Where does the Dura, pia, and arachnoid develop from?
Neural Crest
30
What is the ratio of schwann cells to axons?
1 shwann cell : 1 axon : 1 internode | 1 schwann cell per internode
31
How is the axon basal lamina continuous in the PNS?
-Schwann cells extend over nodes of ranvier
32
What is a schmidt-lanterman cleft?
Areas in the mylenation of axons where cytoplasm has percolated back into the layers of the membrane
33
What Surrounds axons in the PNS?
- Myeln | - Endoneurium
34
What surrounds fascicles in the PNS?
-Perineurium
35
What surrounds nerves in the PNS?
-Epinerurium
36
How are motor nerves repaired?
- Initial wallerian axonal degeneration - Reorganization of proximal segment - Macrophages clean up, Stim schwann cells - Schwann cells proliferate (Neurotrophins) - Schwann cells + BL guide neurons
37
What is a neuroma?
Lost axons that form a swelling when they cannot find their target, can be the source of spontaneous pain
38
In what time period must motor neurons reach muscle after damage?
-18 months
39
In what time period must sensory neurons reach target after damage?
-No time limit
40
What is the function of satellite cells?
- Form an intimate covering layer over the cell bodies in PNS ganglia - Exert a supportive effect, nourishing and regulating the microenvironments of these neurons
41
What does endoneurium consist of?
- reticular fibers - scattered fibroblasts - capillaries
42
What is the function of the perineurium?
- regulated diffusion into the fascicle | - make up blood-nerve barrier to maintain fibers' microenvironment

Histology Term 1 (15 decks)

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