Neural Control of Breathing

Question 1

How do we tell the diaphragm and external intercostals to contract for inspiration?

Answer 1

• Respiratory centres located in the brainstem (medulla oblongata and pons specifically)
• For normal quiet tidal volume breathing – only need diaphragm to contract
• Signal originates at the back of the medulla in dorsal inspiratory region
• Neurones spontaneously fire off in a fire-stop-fire-stop pattern
• With an intact spinal cord they send signals to C3 C4 C5
• Send signal to phrenic nerve which innervates the diaphragm