NEURAXIAL Flashcards

1
Q

What are the 5 divisions of the spinal column and how many vertebrae are present in each?

A

33 vertebrae
C5 - T12 - L5 - S5 - C4

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2
Q

What are the anatomic borders of the facet joint?

A

Formed by the superior articular process of one vertebra and the inferior articular process of the vertebrae directly above.

Injury to the facet joint can compress the spinal nerve that exits the respective intervertebral foramina causing pain and muscle spasm along the associated dermatome

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3
Q

Order the 5 ligaments of the spinal column from posterior to anterior

A

Supraspinous - interspinous - ligamentum flavum - PLL - ALL

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4
Q

List all of the structures and spaces between the skin and spinal cord as they would be encountered during a subarachnoid block

A

skin - SQ - supraspinous - interspinous - ligamentum flavum - epidural - dura - subdural - arachnoid - subarachnoid - pia mater - spinal cord

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5
Q

What are the boundaries of the epidural space?

A

Cranial border = foramen magnum
Caudal border = Sacrococcygeal ligament
Anterior = PLL
Lateral = vertebral pedicles
Posterior = ligamentum flavum, vertebral lamina

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6
Q

What happens when you inject LA into subdural space during SAB? vs epidural

A

Epidural = high spinal w/delayed onset (15 - 20m)

Spinal = failed spinal

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7
Q

What is the plica mediana dorsalis, and what is its significance?

A

Controversial existence
Band of CT that courses between the ligamentum flavum and the dura mater. Conceivably creates a barrier that impacts the spread of meds in epidural space. Possible etiology for difficult epidural placement as well as unilateral epidural block

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8
Q

Important dermatome levels

A

C6 = thumb
C7 = pointer, middle
C8 = ring, pinky
T4 = nipple
T6 = xiphoid process
T10 = umbilicus
T12 = pubic symphysis
L4 = anterior knee

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9
Q

Site of action for spinal vs. epidural

A

Spinal = myelinated preganglionic fibers of the spinal nerve roots

Epidural = infuse thru the dural cuff before they can block the nerve roots. They also leak through the intervertebral foramen to enter the paravertebral area.

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10
Q

What contributes to the spread of LA in subarachnoid space?

A

Patient position
Baricity
Dosing
Site of Injection

Volume of CSF
Density of CSF

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11
Q

What is the primary determinant for spread of epidural anesthesia

A

Volume

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12
Q

Differential blockade for spinal anesthesia

A

1st = autonomic (+2 - 6 levels above motor)
2nd = sensory (+ 2 levels above motor)
3rd = motor

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13
Q

Differential blockade for epidural anesthesia

A

Only sensory & motor differential
Sensory is 2 - 4 dermatomes higher than motor block

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14
Q

A-Alpha

A

Skeletal muscle motor & proprioception
Blocked last
Heavily myelinated
12 - 20 um

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15
Q

B-Beta Fibers

A

Touch, Pressure
Blocked last
Heavy myelination
5 - 12 um

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16
Q

Gamma Fibers

A

Skeletal muscle tone
Blocked third
Medium myelination
3 - 6 um

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17
Q

Delta

A

Fast pain, temperature, touch
Blocked third
medium myelination
2-5 um

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18
Q

B Fibers

A

Preganglionic Fibers
Blocked 1st
Light myelination
3

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19
Q

C Fiber Sympathetic

A

Sympathetic = postganglionic ANS
Blocked 2nd
No myelination
0.3 - 1.3

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20
Q

C Fiber

A

Slow pain, temperature, touch
Blocked 2nd
No myelinaiton
0.4 - 1.2

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21
Q

Respiratory effects of neuraxial

A

Impaired intercostal muscles (inspiration and expiration)
Abdominal muscle (ability to cough and clear secretions)

If there is apnea, it’s d/t hypoperfusion

22
Q

GI function & neuraxial

A

The gut receives PSNS from CN10 and SNS from sympathetic chain T5 - L2. Neuraxial increases PSNS = sphincters relaxed, peristalsis increased

23
Q

What is the risk of neuraxial anesthesia with the patient with a coagulopathy? What labs?

A

Plt < 100
PT, aPTT, bleeding time 2x normal

24
Q

Cardiac pathologies that are a c/i

25
CSF s/g
1.002 - 1.009
26
Lordosis
T7
27
Kyphosis
L3, C5
28
Cutting point spinal needles
Quinke, Pitkin
29
Pencil point needles
Sprotte, whitacre ( has a whiittle hole)
30
Rounded bevel spinal needle
Green
31
Name the three epidural needles
Tuohy 30 degrees Hustead 15 degrees Crawford 0 degrees
32
Caudal dosing in children
Sacral = 0.5 mL/kg T10 = 1 mL/kg Mid Thoracic = 1.25 mL/kg
33
Caudal dosing in adults
Sacral = 12 - 15 mL Low Thoracic (T10) = 20 - 30
34
Absolute c/i to caudal
spina bifida, meningitis, meningomyelocele of sacrum
35
MOA of neuraxial opioids
-afferent pain tx inhibition in rexed lamina 2 -decreased camp -decreased ca -increased k
36
sufentanil intrathecal & epidural dose
5 - 10 mcg 25 - 50 mcg
37
fentanyl dosing
10 - 20 mcg 50 - 100 mcg
38
hydromorphone
0.5 - 1 mg (e only)
39
meperidine
10 mg 25 - 50 mg
40
morphine
0.25 - 0.3 mg 2 - 5 mg
41
lipophilicity
sufent > fent > meperidine > dilaudid > morphine
42
Glycoprotein IIb/IIIa Antagonists - How long do you wait before neuraxial
Ex = tirofiban, eptifibatide, abciximab (TEA) Tirofiban & Eptifabatide = 4 - 8 horus Abciximab = 24 - 48 hours
43
Thienopyridine - how long do you wait
Clopidogrel - 5- 7 days Prasurgrel - 7- 10 days Ticlopidine - 10 days *restart in 24 hours*
44
Unfractionated heparin
Low dosing (< 5k) = 4 - 6hours High dosing < 20,000 = 12 hours > 20, 000 = 24 hours *restart in 1 hour* *hold 4 - 6 hours before removal*
45
Warfaarin
5 days and verify INR
46
10a anti-factor (oral)
apixaban betrixabaan edoxaban rivoraxaban WAIT 72 hours prior to placing removing = 6 hours before 1st dose
47
Thrombolytic agents
i.e., tpa, streptokinase, alteplase, urokinase ABSOLUTE C/I
48
Conus medullaris in adult
L1 L2 vs L3 in kids Subarachnoid space ends @ S2, vs S3 (kids)
49
Cauda equina cause
Neurotoxicity 5% lido & microcatheters = RF
50
TNS
Cause = positioning, muscle spasm RF = lido, lithotomy, ASC, knee arthro s/s = back/butt pain that radiates to both legs *develops in 6 - 36 hours, persists for 7 days*
51
Most common organism for post-spinal meningitis
STREPTOCOCCUS VIRIDANS FROM THE MOUTH