Neuro

Question 1

Failure of vertical gaze lesion location?

Answer 1

Dorsal midbrain

Question 2

Secondary prevention for future strokes?

Answer 2

Clopidogrel

Question 3

String of pearls/beaded appearance of carotid or renal artery?

Answer 3

Fibromuscular dysplasia

Question 4

Ropinirole class?

Answer 4

Dopamine agonist

Question 5

First line for relapsing remitting MS?

Answer 5

B-interferon

Question 6

AED with no warfarin interaction?

Answer 6

Lamotrigine

Question 7

Most common cancer assoc with LEMS?

Answer 7

Small cell lung

Question 8

Weakness and dry mouth, absent tendon reflexes?

Answer 8

Think LEMS

Question 9

Crossed neurological signs - think?

Answer 9

Brainstem lesion/involvement

Question 10

Classical MRI sig in vCJD?

Answer 10

Pulvinar sign of the thalamus

Question 11

Lateral medullary syndrome arteries?

Answer 11

Vertebral
PICA

Question 12

Negative prognostic factors in GBS?

Answer 12

Age >40
Rapid onset
Confirmed bacterial illness - especially campylobacter
High GM1
Ventillation

Question 13

CCB used in SAH?

Answer 13

Nimodipine

Question 14

Tinnitus (unilateral), lack of corneal reflex?

Answer 14

Vestibular schwannoma

Question 15

Combination of 3rd, 4th, 1st and 2nd branches of 5th, and 6th nerve palsy?

Answer 15

Cavernous sinus lesion

Question 16

Mention of a ‘shawl-like or cape’ distribution?

Answer 16

Syringomyelia

Question 17

First line for occular pyridostigmine? Starting dose?

Answer 17

Pyridostigmine
30mg QDS

Question 18

Global wasting of the hand muscles? Lesion where?

Answer 18

T1

Question 19

Jerk/oscillating nystagmus lesion location?

Answer 19

Cerebellum

Question 20

Meningitis prophylaxsis for contacts?

Answer 20

Rifampicin or cipro

Question 21

GN in SLE?

Answer 21

Diffuse proliferative

Question 22

First line to prevent angina?

Answer 22

CCB / BB

Question 23

First line for migraine (if not super frequent)

Answer 23

Paracetamol with metaclopramide

Then naproxen

Then triptan

Question 24

Most common visual field defect in IIH?

Answer 24

Enlarged blind spot(s)

Question 25

Cluster headache prevention?

Answer 25

Verapamil

Question 26

Largely the first line AED?

Answer 26

Lamotrigine

Question 27

Good AED in liver impairment?

Answer 27

Topiramate

Question 28

Topiramate SEs?

Answer 28

Renal stones Loss of appetite and weight loss Peripheral paralysis

Question 29

Contralateral weakness, arm/face more than leg and aphasia, might have dyspraxia, homonymous hemianopia?

Answer 29

MCA

Question 30

Contralateral weakness, leg more than arm. Might be confused, mute, apathetic?

Answer 30

ACA

Question 31

Cortical blindness, CN3, memory loss, hemiballismus?

Answer 31

PCA

Question 32

Parkinsonian with pronounced postural instability?

Answer 32

Think PSP

Question 33

What is the protein abnormality in AD, PSP and FTD?

Answer 33

Tau

Question 34

What do tau inclusions stain with?

Answer 34

Ubiquitin - TDP43

Question 35

Parkinsonism, automonic, cerebellar, pyrimadial/extrapyramidal features?

Answer 35

MSA?

Question 36

What is the protein in MSA?

Answer 36

Alpha-synuclein

Question 37

Myotonic dystrophy type 1 vs 2?

Answer 37

Type 1 - ptosis, facial weakness/wasting, hand myotonia Type 2 - PROXIMAL MD - primarily proximal lower limb weakness and myotonia

Question 38

Progressive ataxic syndrome with marked dorsal column involvement, pes cavus, cardiomyopathy? How is it inherited?

Answer 38

Friedrich's ataxia AR

Question 39

CADASIL gene?

Answer 39

NOTCH3