Neuro Flashcards

(33 cards)

1
Q

What is a primary headache?

A

No underlying cause - migraine, cluster, tension

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2
Q

What is a secondary headache?

A

Has an underlying cause - giant cell arteritis

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3
Q

What are red flags for secondary headache?

A

HIV, immunocompromised, thunderclap, seizure, rash, neck stiffness, red eye, new focal neurology

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4
Q

What is the clinical presentation of a migraine?

A

Two of: unilateral, pulsatile, moderate-severe pain, aggravated by activity
During headache, one of: nausea/vomiting, photophobia, phonophobia

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5
Q

What are migraines?

A

Recurrent throbbing headaches, preceded by aura and associated with nausea, vomiting and visual changes

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6
Q

How long do migraines last?

A

4-72 hours

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7
Q

What can trigger migraines?

A

CHOCOLATE: chocolate, hangovers, orgasms, cheese, OCP, lie-ins, tumult (loud noises), exercise

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8
Q

What visual disturbances can you get with migraines?

A

Chaotic cascading, jumbling, distorted lines, dots, zigzagz, scotoma, hemianopia

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9
Q

What somatosensory disturbances can you get with migraines?

A

Paresthesia (fingers to face)

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10
Q

How is migraine diagnosis made and what should be checked?

A

Clinical diagnosis. Examine eyes (papilloedema), BP, head and neck (scalp, neck muscles, temporal arteries)

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11
Q

How do you treat migraines?

A

Reduce triggers.

Acute: sumatriptan, NSAIDS (avoid paracetamol and ibuprofen), prochlorperazine (antiemetic)

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12
Q

Name an antiemetic used to treat migraines?

A

Prochlorperazine.

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13
Q

When is prevention treatment for migraines indicated?

A

More than 2 attacks per month, acute management required more than twice a week

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14
Q

Name 3 drug classes and an example of each used to treat migraines.

A

Beta-blocker - propranolol
TCA - amitriptyline
Anticonvulsant - topiramate

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15
Q

Define episodic and chronic tension headaches.

A

Episodic: <15 days per month
Chronic: >15 days per month

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16
Q

Describe a tension headache.

A

Bilateral, tight band, non-pulsatile.

17
Q

What advice would you give to a patient with tension headaches?

A

Reassurance, lifestyle advice, limit use of analgesia (<6 days per month)

18
Q

What treatment can be given for tension headaches?

A

Aspirin, paracetamol, NSAIDs, not opioids

Consider TCA

19
Q

What is the pathology of cluster headaches?

A

Unknown. May be due to superficial temporal artery smooth muscle hyper-reactivity to serotonin.

20
Q

When do cluster headaches occur?

A

Once or twice a day at the same time, last between 15 mins - 2 hours.

21
Q

What is the clinical presentation of cluster headaches?

A

Rapid onset, excruciating headache around the eye, temple or forehead.

22
Q

What cranial autonomic symptoms occur with cluster headaches?

A

Ipsilateral watery/bloodshot eye, lacrimation, facial flushing, miosis and ptosis

23
Q

What is the timing or cluster headaches?

A

Clusters lasting 4-12 weeks followed by pain free periods of up to 1-2 years. Can be chronic.

24
Q

How would you treat a cluster headache?

A

Analgesia not helpful. 100% O2 15 mins via non-rebreathable mask (not in COPD).

25
Cluster headache prevention.
1st line - CCB Verapamil Avoid alcohol Prednisolone may help during cluster.
26
Is the trigeminal nerve sensory, motor or both?
Both: V.I - ophthalmic V.II - maxillary V.III - mandibular + motor routes for muscles of mastication
27
Describe trigeminal neuralgia.
Chronic, debilitating condition resulting in intense/extreme episodes of pain.
28
What is the cause of TGN?
Most commonly due to compression of trigeminal by loop of vein/artery.
29
What local pathology is common in younger people with TGN?
Vestibular schwannoma.
30
What is the pathology of TGN?
Compression of CNV resulting in demyelination and erratic pain signalling
31
Pathology at what locations can cause fifth nerve lesions?
Within the brainstem, cerebellopontine angle, petrous bone, cavernous sinus.
32
What is the main RF for TGN?
Hypertension.
33
What are triggers to TGN?
Washing affected area, shaving, eating, talking and dental prostheses.