Neuro ILAs Flashcards

1
Q

What is another name for Marcus Gunn pupil?

A

Relative afferent pupillary defect (RAPD)

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2
Q

What cranial nerve is responsible for pupil constriction?

A

Oculomotor (III)

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3
Q

What would be classed as normal vision using a Snellen chart? (6 metres)

A

6/6

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4
Q

What can the pinhole correction test indicate?

A

If not pinhole does not correct vision, this suggests the problem id not a refractive error (i.e. that that can be corrected with glasses) and is an organic visual disorder.

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5
Q

What is refractive error?

A

Inability of the cornea and lens to direct light rays into proper focus on the retina.

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6
Q

What are Cherry red spots?

A

Red spots seen in the eye on fundoscopy as the result of central artery occlusion

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7
Q

What is amaurosis fugax?

A

Temporary, painless loss of vision in one or both eyes - “a curtain coming down over the eye”

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8
Q

What causes amaurosis fugax?

A

Occlusion of central retinal artery (branch of ophthalmic artery) - can be caused by internal carotid stenosis/TIA.

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9
Q

What is anterior ischaemic optic neuropathy?

A

Loss of vision caused by insufficient blood supply to the optic nerve (posterior choroidal artery).

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10
Q

What is retinal detachment?

A

Retina becoming detached from the blood supply.

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11
Q

How can a gadolinium contrast MRI be used to investigate MS?

A

Can indicate the age of MS lesions - lesions that ‘light up’ indicate active inflammation and are usually less than 3 months old.

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12
Q

What investigations can be used to determine the cause of unilateral vision loss?

A
  1. History/examination
  2. Fundoscopy
  3. Fluorescein angiography
  4. MRI
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13
Q

What is the aetiology of optic neuritis?

A

Demyelination inflammation of the optic nerve.

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14
Q

Symptoms of optic neuritis.

A

Unilateral blurred vision, pain behind the orbit, worse when moving the eye. May be loss of colour vision. Worse in the shower, hot climate or when exercising.

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15
Q

Signs of optic neuritis.

A

Visual field loss, relative afferent pupillary reflex.

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16
Q

Treatment of optic neuritis.

A

May improve on its own. Steroids may increase the speed of recovery but not amount of vision recovery.

17
Q

What is the typical initial presentation of MS.

A

Optic neuritis, motor weakness (UMN signs), sensory disturbance (numbness and dysesthesia)

18
Q

What are clinically isolated symptoms?

A

First attack of demyelination.

19
Q

What is required for a diagnosis of MS?

A

Two symptomatic episodes (lasting more than 24 hours) disseminated in space (clinically or on MRI) and time (1 month apart).

20
Q

What is the pathophysiology of MS?

A

Inflammatory demyelination disease of the CNS caused by activated immune cells causing ‘plaques’ to form.