Neuro Flashcards

(34 cards)

1
Q

2 types of intervertebral

  • name
  • what happens
  • type of degen
  • progression timeline
A

1) Extrusion
- chondroid degeneration of nuccleus pulposus –> NP protrudes into spinal cord
- Hansen type 1
- acute

2) Protrusion
- collagen of annulus fibrosus lose strength –> pushes on spinal cord
- hansen type II
- chronic

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2
Q

IVDH extrusion

  • breed
  • age
  • location
  • signs
  • dx
  • tx
  • prognosis
A
  • chondrodystrophic breeds, esp Dacshund
  • 3-6yo
  • T11-L3 or cervical
  • signs depend on location, acute onset
  • spinal rads , myelogram, CT, MRI
  • conservative tx: cage rest, NSAID, opiods
  • sx: hemilaminectomy or pediculectomy if thoraco-lumbar, ventral slot if cervical
  • good if deep pain present
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3
Q

Indication for emergency surgery in IVDH extrusion

A
  • absent deep pain
  • quick deterioration
  • tetraplegia, non-ambulatory
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4
Q

Fibrocartilaginous embolic myelopathy

  • pathophys
  • breed
  • presentation
  • dx
  • tx
A
  • emobli of nucleus pulposus –> spinal cord ischemia
  • non-chondrodystrophic large breed, min schnauzer
  • acute, non-progressive, asymmetrical, non-painful
  • MRI, rule out others
  • supportive, physio
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5
Q

Spinal cord trauma

  • primary vs secondary
  • tx
A
  • primary = damage to spinal cord directly vs secondary = damage from decr perfusion
  • tx for primary: sx decompression, stabilize
  • tx for secondary: maintain perfusion
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6
Q

IVDH protrusion type

  • presentation
  • breed
  • age
  • dx
  • tx
A
  • chronic/slow dev
  • non-chondrodystrophic large breed
  • > 5yo
  • myelogram, CT, MRI
  • conservative tx: rest, steroids
  • sx: low success
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7
Q

Atlantoaxial sublux

  • what
  • causes
  • sign/presentaiton
  • dx
  • tx
A
  • instability btw C1-C2
  • congenital (small breed <1yo) or acquired (e.g. trauma)
  • chronic or acute, neck pain, +/-dyspnea
  • xray*, myelogram, CT, MRI
  • conservative tx: splint next
  • sx: pin to stablize
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8
Q

Degenerative myelopathy

  • cause
  • location
  • breed, age
  • presentation
  • dx
  • tx
  • prognosis
A
  • genetic
  • T3-L3, white matter
  • Large breed >5yo
  • chronic, progressive, no pain
  • genetic test, histo
  • support, physio
  • poor
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9
Q

Caudal cervical spondylomyolopathy (aka wobbler’s syndrome)

  • what
  • 2 forms, who’s predisposed to each, eg?
  • location
  • dx
  • tx
  • prognosis
A
  • cervical stenosis from vertebral malformation/misarticulation
  • i) Disc-associated: large breed, middle age, IVD
  • ii) Osseous-assocuated: giant breed, <3yo, DJD
  • C6-T2 > C1-C5
  • myelogram, CT, MRI
  • conservative tx: rest, physio, anti-inflamm
  • sx: ventral slot for disc-assoc., dorsal laminectomy for osseous-assoc.
  • good but can reoccur
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10
Q

Degenerative lumbosacral stenosis

  • what
  • signalment
  • sign
  • dx
  • tx
  • prognosis
A
  • compression of cauda eq. due to degeneration
  • large breed, middle age or older, male
  • lumbosacral pain, hind weakness, urinary issues, tail paralysis
  • MRI
  • conservative tx: anti-inflammatory. rest
  • sx: dorsal laminectomy
  • good but poor if incontinent
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11
Q

Ddx peripheral nerve dz vs neuromuscular junction dz vs muscle dz

A
  • peripheral n.: no reflexes, neurogenic m. atrophy
  • NMJ: normal reflexes
  • m.: normal reflexes, severe m. atrophy
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12
Q

Brachial plexus avulsoin

  • cause
  • spinal cord seg
  • potential concurrent signs
  • tx
  • prognosis predictor
A
  • trauma, neoplasia
  • C6-T2
  • horner’s, absent cutaneous trunci ipsilat
  • support, amputation
  • deep pain present
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13
Q

Causes of polyneuropathies

  • acute
  • chronic
A
  • coonhound paralysis

- endocrine (hypothyroid, DM), paraneoplastic (insulinoma)

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14
Q

Acute idiopathic polyradiculoneuritis

  • pathophys
  • dz progression
  • tx
A
  • immune mediated
  • progressive –> stable –> slow recovery
  • support, physio,
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15
Q

Myasthenia gravis

  • what
  • cause
  • dx
  • tx
  • prognosis
A
  • no ACh transmission
  • congenital, autoimmune, thymoma
  • AchR antibody conc, edrophonium test, xray
  • anti-AchE (pyridostigme, neostigme), support
  • guarded
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16
Q

See clin med for neuro exam stuff

17
Q

Encephalitis

  • causes
  • dx
  • tx
A
  • infection, immune mediated (dogs)
  • histo
  • immunosuppression (eg steroids)
18
Q

2 types of necrotizing encephalitis and their ddx

- dx

A

1) necrotizing ME: affects white and grey matter
2) necrotizing leukoencephalitis: affects brain stem and cerebral white matter
- MRI, CSF, rule out other causes

19
Q

Otitis media/interna

- just a card to remind you this exists XD

20
Q

Idiopathic vestibular dz

- signalment

A
  • geriatric dogs, all age cats
21
Q

Bilat vestibular syndrome signs

A
  • no head tilt
  • no nystagmus
  • wide-base stance
  • wide side-to-side head mvmt
22
Q

Paradoxical vestibular dx

  • what
  • signs
A
  • loss of inhibitiion from cerebellum

- head tilt contralat to lesion, proprioceptive deficit ipsilat to lesion

23
Q

Seizure stages

A
  • prodromal: before seizure where changes in sensory
  • aura: signs of seizure at start
  • ictus: seizure
  • post-ictus
24
Q

Causes of epilepsy

A
  • genetic
  • structural: ie some other dz causing it
  • idiopathic
25
what age do genetic epilepsies usually present?
- 6m - 6y | - inter-ictal normally normal
26
Structural epi
- inter-ictal have abn normally
27
When do congenital epi present usually?
<6mo
28
3 tiers of confidence to dx idiopathic epi
1: minimun work up +/- few select database 2: baseline BW + some advance database 3: all above EEG - all these tests are normal
29
When to start tx for epi
- structural epi - status epi - >2 epi in 6m - prolonged and abn post-ictal periods
30
Side effects of phenobarb
- PU/PD/PP - sedation - liver tox - BM supp
31
side effects of KBr
- PU, PD, PP | - fetal to some cats (bronchopneumonia)
32
Zonisamide rxns
- idiosyncratic hepatic necrosis | - idio renal tubular acidosis
33
Status epi definition
epi more than 5min or 2+ seizure with no recovery
34
Emerg tx drugs for seizure
- diazapam - pheno - propofol - inhalant