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Flashcards in Neuro-Drugs Deck (186):
1

Which family of drugs contain acebutolol

Beta 1 blocker

2

Does edrophonium cross into the CNS

No

3

What is the location of target receptor for estrogens

Nuclear estrogen receptors

4

What is homatropine used to treat

Ophthalmology

5

What is Trihexyphenidyl used to treat

Movement disorders such as tremors and rigidity in Parkinson’s (M1 antagonist)

6

Which family of drugs contain tiotropium

Antimuscarinic

7

What is procyclidine used to treat

Movement disorders

8

Which family of drugs contain cyclopentolate

Antimuscarinic

9

Which family of drugs contain Acetylcholine

Direct acting Cholinomimetics

10

Which family of drugs contain dicyclomine

Antimuscarinic

11

Which family of GPCR ligands contains histamine

Biogenic amines

12

Which family of GPCR ligands contains prostacyclin

Lipids

13

Which family of drugs contain hyoscyamine

Antimuscarinic

14

What are the side affects of alpha blockers

Orthostatic hypotension
Reflex induced tachycardia

15

Which family of drugs contain dobutamine

Beta agonists

16

What is the target for spiralactone

Antagonist for aldosterone receptor

17

Which family of drugs contain ephedrine

Increased release and direct adrenergic receptor agonists

18

Which family of drugs contain nadolol

Beta 1 and 2 blockers

19

What is the target for succinylcholine

Antagonist at NMJ

20

Which family of GPCR ligands contains opioids

Peptides/proteins

21

What is the result of using etoposide

Causes DNA, activation of p53 and apoptosis

22

What type of receptor is used to transmit Leptin

JAKSTAT

23

What is the target for digoxin

Sodium/potassium pump

24

Which drug is used for cardiogenic shock

Dopamine
Dobutamine

25

What is solifenacin used to treat

Urinary disorders (selective M3 antagonist)

26

Which family of GPCR ligands contains ADP

Nucleotides

27

Which family of drugs contain procyclidine

Antimuscarinic

28

What conditions is bethanechol used to treat

Non obstructive GI issues
Non obstructive urinary issues

29

Which antimuscarinic drug is used for a longer time of action

Tiotropium (M3 antagonist)

30

Which family of drugs contain Trihexyphenidyl

Antimuscarinic

31

What type of receptor is used to transmit erythropoietin

JAKSTAT

32

Which family of drugs contain Physostigmine

Cholinesterase inhibitors

33

What is neostigmine used to treat

Myasthenia gravis
Reverse nondepolarizing NMJ agents (curare)
Urinary retention

34

What is the location of target receptor for progesterone

Nuclear progesterone receptors

35

Which family of drugs contain fesoterodine

Antimuscarinic

36

What is methacholine used for

An asthma challenge for pulmonary testing

37

Which family of drugs contain tolterodine

Antimuscarinic

38

Which family of drugs contain selegiline

Inhibators of MAO

39

What is the location of target receptor for glucocorticoid

Nuclear glucocorticoid receptors

40

What is ritodrine used to treat

Premature labor

41

Which family of drugs contain Atropine

Antimuscarinic

42

Which family of drugs contain isoproterenol

Beta agonist

43

Which family of drugs contain Scopolamine

Antimuscarinic

44

Which family of drugs contain methacholine

Direct acting cholinomimetics

45

Which family of drugs contain fenoldopam

Dopamine agonists

46

What is phyridostimgine used to treat

Long term treatment for myasthenia gravis

47

What is carbachol used to treat

Acute angle glaucoma

48

Which family of GPCR ligands contains norepinephrine

Biogenic amines

49

What is tropicamide used to treat

Ophthalmology

50

Which family of drugs contain penylephrine

Alpha antagonist (alpha 1)

51

Which family of drugs contain tropicamide

Antimuscarinic

52

Which family of drugs contain oxybutynin

Antimuscarinic

53

Which family of GPCR ligands contains Thromboxane A2

Lipids

54

What is the overall result of bethanechol

Increased secretion of gut and urinary tract

55

What type of receptor is used to transmit NGF

Tyrosine kinase

56

Which family of drugs contain darifenacin

Antimuscarinic

57

What is Dicyclomine used to treat

Gastrointestinal disorders

58

What type of receptor is used to transmit PDGF

Tyrosine kinase

59

Which family of drugs contain pilocarpine

Direct acting cholinomimetics

60

What class of drug is given for prevention of premature labor

Beta 2 agonist

61

What is varenicline used to treat

Cessation of smoking

62

Which family of drugs contain Pyridostigmine

Cholinesterase Inhibators

63

Which family of drugs contain norepinephrine

Alpha and Beta agonists

64

What type of receptor is used to transmit IGF-1

Tyrosine Kinase

65

Which family of GPCR ligands contains Epinephrine

Biogenic amines

66

Which class of drug is given for glaucoma

Alpha 2 agonist

67

What type of receptor is used to transmit EGF

Tyrosine kinase

68

What is phenylephrine used to treat

-nasal congestion
-ophthalmology
-

69

Which family of drugs contain Echothiophate

Cholinesterase Inhibitors

70

What is dobutamine used to treat

Beta 1 > beta 2
Increased heart rate, contractility, CO

71

What are the treatments for bronchial asthma

Beta-2 agonists
Albuterol
Terbutaline

72

What is tolterodine used to treat

Adult urinary incontinence (M2 antagonist)

73

Which family of drugs contain atenolol

Beta 1 blockers

74

What type of receptor is used to transmit interleukin 2-10,15

JAKSTAT

75

Which family of drugs contain betaxolol

Beta 1 blockers

76

Which family of drugs contain Pralidoxime

Cholinesterase regenerator

77

What is the mechanism of action of Prazosin

Alpha 1 Adrenergic receptor antagonist

78

Which drug should not be given for a depolarizing NMJ blocking agent

Acetylcholine esterase inhibitor

79

What type of drug class is propranolol

Beta blocker

80

What is the property of binding and target for phenoxybenzamine

Irreversible binding to alpha receptors

81

Which family of drugs contain phentolamine

Nonselective alpha 1 and 2 antagonist

82

Which family of GPCR ligands contains Acetylcholine

Biogenic amines

83

Which family of drugs contain Galantamine

Cholinesterase Inhibators

84

Which family of GPCR ligands contains Glutamate

Aminoacids

85

What is biperiden used to treat

Movement disorders

86

What type of receptor is used to transmit VEGF

Tyrosine kinase

87

What is orphenadrine used to treat

Movement disorders

88

What is the result of result of carbachol

Pupillary constriction

89

What is hyoscyamine used to treat

Gastrointestinal disorders

90

Which family of drugs contain pindolol

Beta 1 and 2 blockers

91

Which drug is used in long term treatment for hypertension

Alpha 2 agonist

92

What is the effect of phenylephrine administration

Slowed heart rate (baroreflex response)
Increased blood pressure
Mydriasis
Decreased nasal secretion

93

What is the effect on the level of ENaC and Na/K ATPase with the administration of spironolactone

Decreased expression of ENaC and sodium/potassium pump

94

What is the result of Prazosin

Anti hypertension drug

95

Which family of drugs contain cocaine

Inhibition of NE and DA reuptake

96

Which drug is used for chronic hypotension

Ephedrine

97

Which family of drugs contain homatropine

Antimuscarinic

98

What is the property of binding and target for phentolamine

Reversible binding to alpha receptors

99

What are the overall effects of pilocarpine

Increased salivation
Accommodation of lens
Increase aqueous humor outflow
Meiosis

100

What is terbutaline used to treat

Prevents premature labor

101

Which family of drugs contain bethanechol

Direct acting cholinomimetic

102

Which drug is used in hypertension emergencies

Fenoldopam (dopamine)

103

Which family of GPCR ligands contains Angiotensin

Peptides/protein

104

Which family of drugs contain penbutolol

Beta 1 and 2 blockers

105

What is atropine used to treat

Heart block (increased AV node conduction) (M2 antagonist)
Cholinergic poisoning (organophosphates and AChE inhibators) (M1 anatgonist)
Opthamalogy (M1)

106

Which family of drugs contain carbachol

Direct acting cholinomimetics

107

Patients on Varenicline need to be watched for which symptom

Depression and suicidal thoughts

108

What can edrophonium be used to test for

Given to see if its AChE inhibator poisoning or myasthenia gravis

109

What is the use of dobutamine

Short term use in acute heart failure

110

Which family of drugs contain Donapezil

Cholinesterase Inhibators

111

What drug is used in induction of mydriasis for eye examination

Phenylephrine (alpha 1 agonist)

112

Which family of GPCR ligands contains serotonin

Biogenic amines

113

Which eye related disorder is contraindicated with muscarinic antagonists

Glaucoma

114

What is physostigmine used to treat

Atropine overdose

115

What type of receptor is used to transmit growth hormone (somatostatin)

JAKSTAT

116

Which family of drugs contain methylphenidate

Increased DA and NE release, decreased reuptake

117

Which family of drugs contain Neostigmine

Cholinesterase Inhibitors

118

What is tiotropium used to treat

Respiratory disorders such as asthma and COPD (M3 antagonist)

119

Which family of drugs contain Endrophonium

Cholinesterase Inhibitors

120

What is the target of verapamil

L type calcium channel

121

Which family of GPCR ligands contains leukotrienes

Lipids

122

What is isoproterenol used to treat

Asthma and respiratory distress

123

Which family of drugs contain varenicline

Direct acting cholinomimetics

124

Which family of drugs contain albuterol

Beta agonist

125

Which family of drugs contain guanethidine

NE release inhibator

126

What is the drug given fro stress urinary incontinence

Ephedrine

127

What is the result of using spironolactone

Increase loss of salt and water, leading to decrease in blood volume and BP

128

What is glycopyrrolate used to treat

Gastrointestinal disorders

129

Which family of drugs contain biperiden

Antimuscarinic

130

What is the location of target receptor for mineralcorticoid receptors

Nuclear mineralcorticoid receptors

131

What is the result of verapamil

-Decreased arythmias
-decreased oxygen use and chest pain
-Decreased hypertension
-Constipation

132

Which family of drugs contain phenoxybenzamine

Non selective receptor antagonist

133

What is phentolamine used to treat

Cocaine toxicity
HTN crisis
Pheochromocytoma

134

Which family of drugs contain Ambenonium

Cholinesterase Inhibators

135

What is Donepezil used to treat

Treatment of Alzheimer’s

136

What is ipratropium used to treat

Respiratory disorders such as asthma and COPD (M3 antagonist)

137

What is the use of dopamine

Congestive severe heart failure with reduced renal perfusion

138

Which family of drugs contain Propranolol

Beta 1 and 2 bloackers

139

Which family of drugs contain amphetamines

INcreased release of DA and NE, Decreased reuptake

140

What type of receptor is used to transmit Interferons

JAKSTAT

141

Which family of drugs contain lacetalol

Mixed beta and alpha 1 blocker

142

What is rivastigmine used to treat

Alzheimer’s disease

143

What is Benztropine used to treat

Movement disorders such as tremors and rigidity in Parkison’s (M1 antagonist)

144

What is the location of the receptor for thyroid hormones

Nuclear receptors

145

What is scopolamine used to treat

Motion sickness (M1 antagonist)
Ophthalmology

146

What is the target for dobutamine

Agonist for Beta 1 adrenergic receptors

147

What is the location of target receptor for Androgens

Nuclear androgen receptors

148

What is given for poisoning of organophosphates or other cholinesterase inhibitors

-Atropine (crosses into CNS and affects mAChR)
-Pralidoxime (affects n and mAChR to get rid of flaccid paralysis)

149

Which drug is used for Hypotensive emergencies

-Norepinephrine
-phenylephrine

150

Which family of drugs contain metyrosine

Tyorisine hydroxylase inhibator

151

What is cevimeline used to treat

Dry mouth associated with Sjegren’s

152

Which family of drugs contain Rivastigmine

Cholinesterase Inhibitors

153

What is the result of acetylcholinesterate inhibitor toxicity

DUMBBELS
-Flaccid paralysis

154

Which family of GPCR ligands contains aminoacids

GABA

155

What is pilocarpine used to treat

Acute angle glaucoma
Dry mouth associated with Sjogren’s

156

What is Oxybutynin used to treat

Urinary incontanence post surgery (Selective M3 antagonist)

157

Which family of drugs contain trospium

Antimuscarinic

158

Which family of GPCR ligands contains Adrenocorticotropin (ACTH)

Proteins/peptides

159

Which family of drugs contain Mecamylamine

Ganglion blockers

160

What is Galantamine used to treat

Alzheimer’s disease

161

Which family of drugs contain Tacrine

Cholinesterase inhibitors

162

What is trospium used to treat

Bladder incontinence (non selective antagonist)

163

Which family of GPCR ligands contains dopamine

Biogenic amines

164

Which family of drugs contain solifenacin

Antimuscarinic

165

What is the target of etoposide

Inhibits topoisomerase 2

166

What is cyclopentolate used to treat

Ophthalmology

167

What type of receptor is used to transmit insulin

Tyrosine kinase

168

Which family of drugs contain terbutaline

Beta agonist

169

What is endrophonium used to treat

Transiently used to treat myasthenia gravis

170

Which family of GPCR ligands contains Adenosine

Nucleotides

171

Which family of drugs contain cevimeline

Direct acting cholinomimetic

172

Which family of drugs contain organophosphate

Cholinesterase Inhibitor

173

Which family of GPCR ligands contains ATP

Nucleotides

174

Which drugs are given for complete AV block and cardiac arrrest

Epinephrine
Isoproterenol

175

Which family of drugs contain orphenadrine

Antimuscarinic

176

Which family of drugs contain metoprolol

Beta 1 blockers

177

What is the receptor stimulated by carachol

Muscarinic and nicotinic

178

Which family of GPCR ligands contains bradykinin

Peptides/proteins

179

Which family of drugs contain gycopyrrolate

Antimuscarinic

180

What drug is given for a nonpolarizing agent at the NMJ

Neostigmine

181

Which family of drugs contain benztropine

Antimuscarinic

182

What was tacrine used to treat

Dementia

183

Which family of drugs contain phenelzine

Inhibitors of MAO

184

Which family of drugs contain clonidine

Alpha agonist (alpha 2)

185

Which family of drugs contain Ipratropium

Antimuscarinic

186

Which family of drugs contain epinephrine

Alpha and Beta