Flashcards in Neuro Emergencies Deck (52)
Loading flashcards...
1
1. Consciousness has 2 main components what are they?
2. Describe how they are different in Delirium and Dementia?
1. Arousal and Cognition.
2.
Delirium: alteration of both arousal and cognition. Dementia: alteration in cognition, not arousal
2
1. Arousal is controlled by the what?
2. Cognition is controlled by ?
1. ascending reticular activating system (ARAS) in the brainstem.
2. cerebral cortex.
3
AMS - PE
3
1. ABCs; Vital signs
2. Bedside glucose
3. Look quickly for immediate life threats
4
AMS PE
Look quickly for immediate life threats, such as:
5
1. Hypoglycemia
2. Hypotension/ Hypertension
3. Hypoxia
4. Abnormal respirations
5. Hypo/ Hyperthermia
5
AMS PE
Head to toe exam
1. Head? 5
2. Neck? 1
3. CV? 3
4. Pulm? 1
5. Abd? 2
6. Skin? 4
1. Head –
-trauma;
-Pupil size, symmetry, and reactivity.
-Pinpoint pupils: OD vs pontine hemorrhage;
-Blown pupil: uncal herniation;
-Fundi: papilledema
2. Neck – stiffness?
3. CV –
-dysrhythmia (atrial fib),
-murmurs (endocarditis),
-rubs (pericarditis)
4. Pulm-
-symmetry of sounds, rate, wheezes
5. Abd –
-masses?
-Organomegaly? (alcoholic liver, splenic sequestration in sicklers)
6. Skin –
-color,
-turgor (dehydration);
-rashes (petechiae, purura: TTP vs meningococcemia?);
-Infection (cellulitis, fasciitis)
6
AMS – DDx: AEIOU TIPS
A – Alcohol
E – Epilepsy; Electrolytes; Encephalopathy (HTN, Hepatic)
I – Insulin (hyper and hypo); Intuss (peds)
O – Overdose; Opiates
U – Uremia
T – Trauma; Temperature (Hyper and hypo)
I – Infection; Intracerebral hemorrhage
P – Psych; Poison
S - Shock
7
When would you intubate?
GCS less than 8
8
Are they brain dead/herniating?
PE?
6
1. DTR
2. Cranial nerves best they can
3. responsive to pain
4. suction and see if they have a cough or gag reflex
5. dolls eye test- stays in line is bad
6. anyone with a blown pupil is uncle herniation until proven otherwise
9
Status Epilepticus
1. Considered how long without return to preconvulsive neurologic baseline?
2. Traditionally considered to be convulsions > ______, however do not halt treatment!
1. 5 minutes or more of convulsions or 2 or more convulsions in a 5 min interval
2. 30 min
10
Status Epilepticus
Etiologies
6
1. Vascular: stroke, SAH, hypoxic encephalopathy
2. Toxic: drugs, alcohol withdrawal, medications (Isoniazid, TCA’s, chemo agents), AED non-compliance
3. Metabolic: Hyper/hypo-natremia, hypoglycemia, hypocalcemia, liver/renal failure
4. Infectious: meningioencephalitis, brain abscess
5. Trauma
6. Neoplastic
11
Initial Assessment/Treatment of status epilepticus
3
1, ABC’s – O2, airway, BP
Monitor for hypotension
2. Labs:
3. Dx hypoglycemia as cause
12
Initial Assessment/Treatment of status epilepticus
5
1. CBC,
2. BMP,
3. Ca,
4. Mg,
5. AED levels
13
How would you treat status epilepticus if hypoglycemia was the cause? 2
-D50W amp and Thiamine 100 mg IV
-Needs to have thiamine given before dextrose as 20-40% of seizure pts are alcoholics
14
Treatment for status epilepticus:
1. Initially? 2
2. Then? 2
3. Refractory? 4
1. Benzodiazepines are first line
Ativan 4mg IV or Valium 5mg IV
2. Second line
-Fosphenytoin load 20 mg/kg (up to 150 mg/min)
-Valproic acid load 40 mg/kg, 2nd dose of 20 mg/kg
3. Refractory status
-Phenobarb 20 mg/kg,
-Pentobarb,
-Versed gtt,
-Propofol, etc.)
15
Post-ictal State
1. What do we have to differentiate this from?
2. What does the post ictal state consist of? 4
3. tx?
4. Work up?
1. Differentiate post-ictal state and syncope of another cause
2. Post-ictal state
-Usually sleepy and may be confused
-During the possible prior seizure the pt has usually been incontinent
-Tongue bitten
3. Supportive care
4. Work up why seizure occurred
16
Acute Ischemic Stroke
1. Caused by? Results in?
2. Within seconds to minutes of loss of perfusion, an ischemic cascade occurs resulting what?
3. Goal of tx?
1. Caused by the sudden loss of blood circulation to an area of the brain resulting in ischemia and corresponding loss of neurologic function
2. a central area of irreversible infarction surrounded by an area of potentially reversible ischemic penumbra
3. Goal of treatment is to preserve ischemic penumbra
17
Acute Ischemic Stroke
Hx questions?
4
1. Time last known well
2. tPA contraindications?
3. History of diabetes? Seizures?
4. Detailed description of symptoms
18
Acute Ischemic Stroke
Detailed description of symptoms such as
1. What would indicate ICH? 3
2. What about a vertebral or carotid dissection? 2
1. Onset with HA,
2. seizure,
3. syncope .. Possible ICH..
1. Neck pain,
2. history of neck trauma ..
Possible vertebral or carotid dissection
19
PE for acute ischemic stroke?
7
1. Level of consciousness
2. Eye exam
3. CN exam
4. Motor exam
5. Sensory exam
6. Reflexes
7. Cerebellar exam
20
Work up: Acute ischemic stroke:
1. Labs? 6
2. Imaging?
1. Labs:
-POCT BG,
-CBC,
-CMP,
-PT/INR,
-cardiac enzymes,
-EKG
2. Imaging:
-Emergent non-contrast head CT
21
Why do we do a noncontrast CT for acute ischemic stroke? 3
1. Distinguished hemorrhagic from ischemic stroke
2. Defines age and anatomic distribution of stroke
3. Large hypodense areas seen within 3 area can indicate timing of AIS and can predict poor outcome
22
ED-Based Care
Action Time:
1. Door to clinician ___ minutes
2. Door to stroke team ____ minutes
3. Door to CT initiation ____ minutes
4. Door to CT interpretation ____ minutes
5. Door to drug (≥80% compliance) ____ minutes
6. Door to stroke unit admission: How long?
1. ≤10
2. ≤15
3. ≤25
4. ≤45
5. ≤60
6. ≤3 hours
23
ACA stroke symptoms?
4
1. Dysarthria, aphsasia
2. Unilateral contralateral motor weakness (lower > upper)
3. Lower extremity sensory changes
4. Urinary incontinence
24
MCA stroke symptoms? 4
1. Contralateral hemiparesis (face/arms > legs) and hemianopsia
2. Ipsilateral gaze preference
3. Aphasia (if dominant hemisphere)
4. Broca’s/Wernike’s/Global
Hemi-neglect (if non-dominant hemisphere)
25
PCA stroke symptoms? 4
1. Contralateral hemianopsia
2. Cortical blindness
3. Altered mental status
4. Impaired memory
26
Initial Treatment
for ischemic stroke?
7
ABCD’s
1. Airway: intubate for GCS
27
Thrombolytics for Tx of ischemic stroke:
1. What is the drug?
2. Considered in eligible patients treated within how long of symptom onset?
1. Alteplase (IV tPa)
0.9 mg/kg w/ max dose of 90 mg
2. 3-4.5 hours
28
Thrombolytics for Tx of ischemic stroke:
Indications? 3
1. Acute neurological deficit expected to result in significant long-term diasability
2. Non-contrast head CT w/ no hemorrhage
3. Stroke symptom onset clearly identified between 3-4.5 hours before tPa given
29
tPa Contraindications
8
1. SBP > 185 or DBP > 110 (Labetolol 10mg q10 min)
2. CT head w/ ICH or SAH
3. Recent intracranial or spinal surgery, head trauma or stroke (> 3 mos)
4. Major trauma or surgery within 3 mos
5. Hx of ICH or aneurysm/vascular malformation/brain tumor
6. Recent active internal bleeding
7. Platelets 40; INR > 1.7
8. Known bleeding disorder
30
