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Flashcards in neuro i don't know Deck (47):
1

treatment parkinsons

only give treatment when symptomatic. no treatments are neuroprotective.

moa-b inhibitor (rasagiline)

carbidopa/ levodopa

dopamine agonsits- rotigotine

anticholinergic agents

amantadine- glutamate antagonist


2

symptoms associated with parkinsons

depression
fatigue
cognitive impairment
autonomic dysfunction
sleep disturbance

3

complications of levodopa

dyskinesias

4

treatment of psychosis in parkinsons

lozapine

5

mild parkinsons- first line?

rasagilline

6

late stage parkinsons-

rivastigmine

7

diagnosis of parkinsons??

clinical- bradykinesia, resting tremor and ridgidity

8

management of ishchaemic stroke

<4.5 hours- thrombolysis and aspirin after 24 hours

>4.5 hours- aspirin

9

management haemorrhagic stroke

control bp and supportive care.

10

how long off driving if TIA

1 month is single TIA

multiple TIA- 3 months off driving

11

diagnosis of MS

MRI + IV contrast

olgoclonic IgG bands in CSF.

12

treatment of acute MS

high dose steroid (oral or IV)

13

disease modifying drugs MS.

interferon beta
glatirmer
monoclonal antibody (tysabri, fingolomoid in treatment resistant ).
dimethyl fumarate

14

symptomtic management MS - fatigue

assume other underlyig cause.
do FBC, TSH, B12 and vitamin D levels, as well as a brief sleep history. amantadine

15

complication of interferon beta medications

metabolised throuh the liver- moniter hepatic function.

16

why is glatrimer not used first line

takes 6-9 months for clinical effect.

17

MS uscle pains

baclofen antispasmodic

18

MS antidepressant

amitryptalline

19

MS gait impairment

fampridine

K channel blocker that improves condction in demyelinated pathways

20

alzheimers treatment

ach esterase ihibitors- donepazil and rivastigmine

glutamate inhibitors- memantine.

21

most common cause of death in alzeheimers

bronchopneumonia

22

lewy body dementia treatment

rivastigmine

23

scan to diagnose parkinsons

DAT scan

24

investigation pick's disease

CT scan

25

What are pick bodies

Tau protein

26

treatment MND

riluzole-

Na channel blocker

increases liffe expectancy by 3 months

27

definition ALS

damage to upper and lower motor neuron disease- lateral corticospinal tracts.

28

duration of cluster headaches

15 mins

29

Causes of SAH

Bleeding due to trauma, rupture of an aneurysm, and arteriovenous malformation are the main causes of subarachnoid hemorrhage

30

managemenrt of epidural haemorrhage

emergency surgical management

31

after 1 seizure, how many are eventually diagnosed with epilepsy

1/4

32

most commonly fractured bone that results in epidural haematoma

temporal

33

hepatic encephalopathy

Hepatic encephalopathy is a central nervous system complication due to acute liver damage and its inability to metabolize ammonia to urea.

34

neurotransmitter causing vasoconstriction in migrine

The neurotransmitter serotonin is increased during a migraine attack and cause vasoconstriction.

35

pupil causing RAPD in MS

Marcus gunn pupil

36

????, a gamma-aminobutyric acid-B receptor agonist, treats spasticity in multiple sclerosis.

Baclofen, a gamma-aminobutyric acid-B receptor agonist, treats spasticity in multiple sclerosis.

37

where is pain percieved in the brain

the insula lobe

38

name for the connection between spinal cord and the dorsum of the coccyx

conus medullaris connects via the filum terminale

39

what forms the denticulte ligament

pia and arachnoid mater

40

at which level does he spinal cord also have a lateral horn

t1-l2

contains preganglionic sympathetic neurons

41

tectospinal tract

head and neck movement

42

reticulospinal tract

voluntary movement
pons- facilitate purposeful movement
medulla- inhibit unwanted movement

43

vestibulospinal tract

extensor muscles

44

layers of the cerebellum

molecular
purkinje
granule

45

where to afferents arrive in the cerebellum

the granule layer

46

where in the cerebellum do efferents leave from

the purkinje layer

47

which cn does not synapse in the thymus

CN 1