Neurologic Dysfunction 2 Flashcards

1
Q

What is the sympathetic nervous system

A

Increase heart rate, blood pressure
Dilate pupils, bronchioles
Blood from the GI, skin to skeletal muscles, brain

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2
Q

What is the parasympathetic system

A

Decrease heart rate, blood pressure
Constrict pupils,
Blood to the GI tract, increased secretions

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3
Q

What is preganglionic

A

Acetylcholine binds cholinergic nicotinic receptors

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4
Q

What is involved in postganglionic sympathetic

A

Epinephrine, norepinephrine-binding adrenergic receptors

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5
Q

What is involved in postglanglionic parasympathetic

A

acetylcholine-binding cholinergic muscarinic receptors

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6
Q

What does α1 adrenergic receptor do

A

constrict blood vessels

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7
Q

Where does α1 happen

A

vasoconstriction in many blood vessels, skin, GI tract, kidney and brain

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8
Q

What does a2 adrenergic receptor do

A

inhibit neurotransmitter release, influence the central control of bp

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9
Q

Where are a2 receptors found?

A

Presynaptically, CNS,

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10
Q

What does B1 adrenergic receptor do

A

increase heart rate and contraction

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11
Q

Where are B1 receptors primarily found

A

Heart

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12
Q

What does B2 adrenergic receptor do

A

bronchodilation, inhibit GI motility, micturition

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13
Q

Where are B2 receptors found

A

Bronchioles, visceral smooth muscles of the Gi tract, uterus, urinary bladder

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14
Q

What do the actions of the B2 receptor by smooth muscle relaxation facilitate

A

Respiration,
Inhibit Gi tract motility,
Inhibit labor, and Delay need of micturition

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15
Q

What do B3 adrenergic receptors do

A

regulate fat breakdown, thermogenesis

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16
Q

Where are B3 receptors found

A

In adipose tissue

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17
Q

How are neurotransmitters removed from synapse

A

By reuptake or degraded by enzymes

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18
Q

Where are cholinergic neurotransmitter released from

A

from autonomic preganglionic neurons, parasympathetic post ganglionic neurons, somatic motor neurons

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19
Q

What are the three levels of somatic sensation

A

1: detect the sensation
2: neurons communicate with reflex and sensory pathways in the spinal cord; sends message to thalamus
3: relay info from thalamus to cerebral cortex

20
Q

What are the two subdivisions of the anterolateral pathway

A

Paleospinothalamic tract and neospinothalamic tract

21
Q

What is the paleospinothalamic tract

A

To the reticular activating system,

Affects arousal, mood, attention

22
Q

Is paleospinothalamic tract slow or fast

23
Q

What is the main difference between paleospinothalamic and neospinothalamic

A

Paleo goes through the reticular formation

24
Q

What type of pain is associated with paleo

A

chronic pain

25
What is neospinothalamic tract
To the thalamus and parietal cortex, allows localization, identificatin of pain
26
What type of pain is associated with neo
acute pain
27
What does primary somatosensory cortex do
Identifies sensation
28
What does association cortex do
relates sensation to memories, other sensations
29
What are examples of tactile sensations
free nerve endings, hair follicle, pressure/heat
30
What are thermal sensations
Cold, warmth, pain
31
What is position sense
proprioreceptive receptors, stretch-sensitive receptors
32
What are A-delta fibers?
Large, myelinated fibers, Acute pain, "fast pain"
33
What does A-delta fibers release?
Glutamate- excitatory transmitter
34
What are C-fibers?
Small, unmyelinated, | "Slow wave pain", chronic pain
35
What do C fibers release?
Glutamate but mainly substance P- inhibitory
36
What does it mean to have cutaneous, deep somatic, visceral, referred pain
Cutaneous: skin Deep somatic: periosteum, joints, muscles, blood vessels, Visceral: organs Referred: traveling pain from the site of injury
37
What is hyperesthesia
Increased sensitivity
38
What is hyperalgesia
heightened sensitivity to pain
39
What is hypoesthesia
reduced sensitivity
40
What is hypothermia
Abnormally low body temp
41
What is hypoalgesia
decreased sensitivity to pain
42
What is allodynia
feel pain following a normally non painful/ repetitive stimulation
43
What is the specificity theory
Special pain receptors detect pain (nocireceptors)
44
What is pattern theory?
Sensory receptors create pain signals when stimuli are too strong
45
What is gate control theory?
presence of a neural gating mechanism at the segmental spinal cord level could block projection of pain information to the brain
46
What is neuromatrix theory
Brain identifies pain
47
What kind of actions cause deep somatic pain
pressure exerted on bone