Neuron Structure & Function + The Nervous System Flashcards

1
Q

What is the function of sensory neurons?

A

receive and transmit information about an anima;’s environment or its internal physiological state

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2
Q

What is the function of interneurons?

A

receive and transmit information received by sensory neurons and transmits it to motor neurons

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3
Q

What is the function of motor neurons?

A

signal a muscle or gland to cause a response in the body

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4
Q

Where are stimuli received by the neuron?

A

dendrites

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5
Q

Where are synaptic stimuli summed?

A

axon hillock

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6
Q

____ potentials travel through the cell body
____ potentials travel through the axon

A

graded; action

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7
Q

What is membrane potential?

A

a difference in electrical charge across the cell membrane

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8
Q

Resting membrane potential is ____ mV

A

-70

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9
Q

Na+ moves ____ the cell through the ____ Na+ channel

A

into; voltage-gated

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10
Q

K+ moves ____ the cell through the ____ K+ channel

A

out; voltage-gated

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11
Q

The sodium-potasium pump pumps ____ Na+ ions ____ the cell and ____ K+ ions ____ the cell.

A

3 Na+ ions; out
2 K+ ions; into

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12
Q

True or False:
The sodium-potassium pump pumps a net positive charge of ions into the cell.

A

False

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13
Q

At resting potential:
Membrane potential is more negative/positive inside the cell than outside.

A

negative

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14
Q

At resting potential:
There is a greater/lower concentration of Na+ ions outside the cell than inside.

A

greater

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15
Q

At resting potential:
There is a greater/lower concentration of K+ ions inside the cell than outside.

A

greater

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16
Q

Threshold potential is ____ mV.

A

-55

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17
Q

What happens at threshold potential?

A

Na+ voltage-gated ion channels open and the action potential fires.

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18
Q

What is depolarization?

A

an increase in membrane potential from a negative resting potential

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19
Q

List the steps of an action potential.

A
  1. resting
  2. depolarization
  3. peak action potential
  4. repolarization
  5. hyperpolarization
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20
Q

At peak action potential:
Membrane potential is more negative/positive inside the cell than outside.

A

positive

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21
Q

At peak action potential:
There is a greater/lower concentration of Na+ ions outside the cell than inside.

A

lower

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22
Q

At peak action potential:
There is a greater/lower concentration of K+ ions inside the cell than outside.

A

higher

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23
Q

How are chemical gradients formed?

A

from concentration differences

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24
Q

How are electrical gradients formed?

A

from charge separation

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25
What is the flow of chemical gradients?
high concentration --> low concentration
26
What is the flow of electrical gradients?
positive --> negative
27
What kind of ion channels are primarily present at the neuron's dendrites? Why?
ligand-gated ion channels neurotransmitters bind to these channels in the post-synaptic neuron
28
What are the two types of graded potentials?
excitatory postsynaptic potential (EPSP) inhibitory postynaptic potential (IPSP)
29
What happens when a dendrite receives an EPSP?
cell depolarizes more likely to initiate an action potential
30
What happens when a dendrite receives an IPSP?
cell hyperpolarizes less likely to initiate an action potential
31
What are the conditions of an action potential occurring?
if the sum of EPSPs and IPSPs reach the threshold potential
32
How does no summation occur?
multiple EPSPs widely spaced in time do not set off an action potential
33
How does temporal summation occur?
multiple EPSPs arrive quickly at a single synapse
34
How does spatial summation occur?
single EPSPs arrive at the same time at different synapses
35
How does cancellation occur?
an EPSP and IPSP cancel each other out and no action potential occurs
36
How does action potential propagation occur?
depolarization spreads through the axon and triggers more voltage-gated sodium channels to open and more action potentials to occur
37
What is the role of myelin?
insulates the axon and increases the rate of action potentials
38
True or False: Strong stimuli (more concentration) in the synapse cause neurons to fire more frequent action potentials.
True
39
True or False: Synapses are fixed.
False Synapses are not fixed, which allows for neuroplasticity and learning/memory.
40
Where are voltage-gated channels found in the neuron?
cellular membrane
41
Where are ligand-gated channels found in the neuron?
dendrites
42
What are the steps of synapse communication?
1. stimulated by the action potential 2. voltage-gated Ca2+ channels open 3. vesicles at the axon terminals respond to Ca2+ by fusing with the pre-synaptic membrane 4. vesicles perform exocytosis to release neurotransmitters into the synaptic cleft 5. neurotransmitters bind to ligand-gated ion channels in the post-synaptic membrane 6. neurotransmitters are re-absorbed into the pre-synaptic terminal and stored until the next action potential arrives
43
What are the two divisions of the nervous system?
central nervous system and peripheral nervous system
44
What are the components of the central nervous system?
brain and spinal cord
45
What are the components of the peripheral nervous system?
sensory and motor nerves
46
What are the two divisions of the peripheral nervous system?
somatic and autonomic
47
What is the somatic nervous system responsible for?
controlling voluntary activity
48
What is the autonomic nervous system responsible for?
controlling involuntary activity
49
What are the two divisions of the autonomic nervous system?
parasympathetic and sympathetic
50
What does the parasympathetic nervous system do?
rest and digest
51
What does the sympathetic nervous system do?
fight or flight
52
What are afferent neurons?
send information toward the CNS
53
What are efferent neurons?
send information away from the CNS
54
True or False: Simple reflex circuits go through the CNS.
False Simple reflex circuits bypass the brain.
55
How does the patellar reflex work?
1. patellar tendon is struck 2. stretch receptor in muscle responds by sending a signal along the sensory 3. sensory neuron synapses with motor neuron in the spinal cord 4. motor neuron sends signal to muscle, which contracts 5. inhibitory interneuron inhibits contraction of the muscle
56
What is the purpose of the sodium-potassium pump?
to maintain resting membrane potential by pumping a net negative charge (more cations are pumped out the cell than inside)
57
What happens if a myelinated and unmyelinated neuron arrive at different dendrites and deliver EPSPs?
No spatial summation would occur because the myelinated neuron would arrive at the dendrite before the unmyelinated neuron
58
What is the refractory period of the action potential?
The point at which hyperpolarization is occurring; no action potential could occur at this time while the K+ ions are still closing
59
What would happen if the Na+ and K+ voltage gated channels opened at the same time?
no action potential would occur the movement of ions would "cancel" each other out
60
How does morphine affect the synapse over time?
* increases synaptic activity over time * to maintain homeostasis, the body decreases the number of receptors in the post-synaptic membrane in order to decrease synaptic activity back to normal
61
What is an agonist?
a molecule (usually a drug) that mimics existing neurotransmitters