Neurotransmission Flashcards

1
Q

What are the two steps in neurotransmission?

A
  1. Chemical
  2. Electrical
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2
Q

What are the ions inside cell?

A
  1. Positive Potassium ions
  2. Negative Proteins
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3
Q

What are the ions outside of the cell?

A
  1. Positive Sodium
  2. Negative Chloride
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4
Q

What do we rely on to keep the balance?

A

Sodium Potassium Pumps

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5
Q

What is hyperpolarization?

A

The membrane potential is exaggerated, so the difference between inside and outside is greater.

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6
Q

What is depolarization?

A

The membrane potential is diminished, so the difference between inside and outside is lessened.

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7
Q

How does the membrane potential change?

A

Channels and pores on the cell surface allow influx and efflux of ions.

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8
Q

What charge does (intracellular) the cell become during an action potential?

A

Positive.

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9
Q

How does an EPSP happen?

A

EPSP opens sodium ion channels and allows the influx of them into the dendrites.

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10
Q

How does an IPSP happen?

A

IPSP opens chloride ion channels and allows the influx of them into the dendrites.

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11
Q

What are the requirements for the summation of post-synaptic potentials?

A
  1. Spatial Summation: close together in space
  2. Temporal summation: close in time
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12
Q

Do inputs only attach at the dendrites?

A

No, they can attach to the axon and soma as well.

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13
Q

What are voltage-gated ion channels?

A

They are gated channels that open/close in relation to membrane potential. You to depolarize first so ion gates can open.

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14
Q

Where are channels present?

A

Nodes of Ranvier.

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15
Q

Where are chloride channels?

A

Not on the axon.

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16
Q

What is a neurotransmitter?

A

A chemical released by a neuron onto a target site that has an excitatory or inhibitory effect.

17
Q

What are the four steps in chemical transmission?

A
  1. Synthesis
  2. Release
  3. Receptor Action
  4. Inactivation
18
Q

What are the four ways to inactivate?

A
  1. Glia cell reuptake
  2. Enzymatic degradation
  3. Diffusion
  4. Reuptake transporters
19
Q

What are the four classes of NT’s?

A
  1. Monoamines
  2. Amino Acid
  3. Peptide
  4. Transporter Gases